Result Number | Material Type | Add to My Shelf Action | Record Details and Options |
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1 |
Material Type: Artigo
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TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid actionGao, Yuan ; Cao, Erhu ; Julius, David ; Cheng, YifanNature (London), 2016-06, Vol.534 (7607), p.347-351 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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2 |
Material Type: Artigo
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Inhibition of RAS function through targeting an allosteric regulatory siteSpencer-Smith, Russell ; Koide, Akiko ; Zhou, Yong ; Eguchi, Raphael R ; Sha, Fern ; Gajwani, Priyanka ; Santana, Dianicha ; Gupta, Ankit ; Jacobs, Miranda ; Herrero-Garcia, Erika ; Cobbert, Jacqueline ; Lavoie, Hugo ; Smith, Matthew ; Rajakulendran, Thanashan ; Dowdell, Evan ; Okur, Mustafa Nazir ; Dementieva, Irina ; Sicheri, Frank ; Therrien, Marc ; Hancock, John F ; Ikura, Mitsuhiko ; Koide, Shohei ; O'Bryan, John PNature chemical biology, 2017-01, Vol.13 (1), p.62-68 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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3 |
Material Type: Artigo
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K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactionsOstrem, Jonathan M ; Peters, Ulf ; Sos, Martin L ; Wells, James A ; Shokat, Kevan MNature (London), 2013-11, Vol.503 (7477), p.548-551 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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4 |
Material Type: Artigo
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Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitorsJia, Yong ; Yun, Cai-Hong ; Park, Eunyoung ; Ercan, Dalia ; Manuia, Mari ; Juarez, Jose ; Xu, Chunxiao ; Rhee, Kevin ; Chen, Ting ; Zhang, Haikuo ; Palakurthi, Sangeetha ; Jang, Jaebong ; Lelais, Gerald ; DiDonato, Michael ; Bursulaya, Badry ; Michellys, Pierre-Yves ; Epple, Robert ; Marsilje, Thomas H ; McNeill, Matthew ; Lu, Wenshuo ; Harris, Jennifer ; Bender, Steven ; Wong, Kwok-Kin ; Jänne, Pasi A ; Eck, Michael JNature (London), 2016-06, Vol.534 (7605), p.129-132 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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5 |
Material Type: Artigo
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Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonistsZheng, Yi ; Qin, Ling ; Zacarías, Natalia V Ortiz ; de Vries, Henk ; Han, Gye Won ; Gustavsson, Martin ; Dabros, Marta ; Zhao, Chunxia ; Cherney, Robert J ; Carter, Percy ; Stamos, Dean ; Abagyan, Ruben ; Cherezov, Vadim ; Stevens, Raymond C ; IJzerman, Adriaan P ; Heitman, Laura H ; Tebben, Andrew ; Kufareva, Irina ; Handel, Tracy MNature (London), 2016-12, Vol.540 (7633), p.458-461 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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6 |
Material Type: Artigo
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The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1Wylie, Andrew A ; Schoepfer, Joseph ; Jahnke, Wolfgang ; Cowan-Jacob, Sandra W ; Loo, Alice ; Furet, Pascal ; Marzinzik, Andreas L ; Pelle, Xavier ; Donovan, Jerry ; Zhu, Wenjing ; Buonamici, Silvia ; Hassan, A Quamrul ; Lombardo, Franco ; Iyer, Varsha ; Palmer, Michael ; Berellini, Giuliano ; Dodd, Stephanie ; Thohan, Sanjeev ; Bitter, Hans ; Branford, Susan ; Ross, David M ; Hughes, Timothy P ; Petruzzelli, Lilli ; Vanasse, K Gary ; Warmuth, Markus ; Hofmann, Francesco ; Keen, Nicholas J ; Sellers, William RNature (London), 2017-03, Vol.543 (7647), p.733-737 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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7 |
Material Type: Artigo
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X-ray structures and mechanism of the human serotonin transporterColeman, Jonathan A ; Green, Evan M ; Gouaux, EricNature (London), 2016-04, Vol.532 (7599), p.334-339 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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8 |
Material Type: Artigo
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Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activationStaus, Dean P ; Strachan, Ryan T ; Manglik, Aashish ; Pani, Biswaranjan ; Kahsai, Alem W ; Kim, Tae Hun ; Wingler, Laura M ; Ahn, Seungkirl ; Chatterjee, Arnab ; Masoudi, Ali ; Kruse, Andrew C ; Pardon, Els ; Steyaert, Jan ; Weis, William I ; Prosser, R Scott ; Kobilka, Brian K ; Costa, Tommaso ; Lefkowitz, Robert JNature (London), 2016-07, Vol.535 (7612), p.448-452 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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9 |
Material Type: Artigo
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Structure and allosteric inhibition of excitatory amino acid transporter 1Canul-Tec, Juan C ; Assal, Reda ; Cirri, Erica ; Legrand, Pierre ; Brier, Sébastien ; Chamot-Rooke, Julia ; Reyes, NicolasNature (London), 2017-04, Vol.544 (7651), p.446-451 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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10 |
Material Type: Artigo
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Crystal structures of the M1 and M4 muscarinic acetylcholine receptorsThal, David M ; Sun, Bingfa ; Feng, Dan ; Nawaratne, Vindhya ; Leach, Katie ; Felder, Christian C ; Bures, Mark G ; Evans, David A ; Weis, William I ; Bachhawat, Priti ; Kobilka, Tong Sun ; Sexton, Patrick M ; Kobilka, Brian K ; Christopoulos, ArthurNature (London), 2016-03, Vol.531 (7594), p.335-340 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |