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Upadacitinib Induction and Maintenance Therapy for Crohn’s Disease
Upadacitinib Induction and Maintenance Therapy for Crohn’s Disease
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Upadacitinib Induction and Maintenance Therapy for Crohn’s Disease

Loftus, Edward V. ; Panés, Julian ; Lacerda, Ana P. ; Peyrin-Biroulet, Laurent ; D’Haens, Geert ; Panaccione, Remo ; Reinisch, Walter ; Louis, Edouard ; Chen, Minhu ; Nakase, Hiroshi ; Begun, Jakob ; Boland, Brigid S. ; Phillips, Charles ; Mohamed, Mohamed-Eslam F. ; Liu, Jianzhong ; Geng, Ziqian ; Feng, Tian ; Dubcenco, Elena ; Colombel, Jean-Frederic

The New England journal of medicine, 2023-05, Vol.388 (21), p.1966-1980 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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2
Efficacy of Upadacitinib in a Randomized Trial of Patients With Active Ulcerative Colitis
Efficacy of Upadacitinib in a Randomized Trial of Patients With Active Ulcerative Colitis
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Efficacy of Upadacitinib in a Randomized Trial of Patients With Active Ulcerative Colitis

Sandborn, William J. ; Ghosh, Subrata ; Panes, Julian ; Schreiber, Stefan ; D’Haens, Geert ; Tanida, Satoshi ; Siffledeen, Jesse ; Enejosa, Jeffrey ; Zhou, Wen ; Othman, Ahmed A. ; Huang, Bidan ; Higgins, Peter D.R.

Gastroenterology (New York, N.Y. 1943), 2020-06, Vol.158 (8), p.2139-2149.e14 [Periódico revisado por pares]

United States: Elsevier Inc

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3
Efficacy and Safety of Upadacitinib in a Randomized Trial of Patients With Crohn’s Disease
Efficacy and Safety of Upadacitinib in a Randomized Trial of Patients With Crohn’s Disease
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Efficacy and Safety of Upadacitinib in a Randomized Trial of Patients With Crohn’s Disease

Sandborn, William J. ; Feagan, Brian G. ; Loftus, Edward V. ; Peyrin-Biroulet, Laurent ; Van Assche, Gert ; D’Haens, Geert ; Schreiber, Stefan ; Colombel, Jean-Frederic ; Lewis, James D. ; Ghosh, Subrata ; Armuzzi, Alessandro ; Scherl, Ellen ; Herfarth, Hans ; Vitale, Lauren ; Mohamed, Mohamed-Eslam F. ; Othman, Ahmed A. ; Zhou, Qian ; Huang, Bidan ; Thakkar, Roopal B. ; Pangan, Aileen L. ; Lacerda, Ana P. ; Panes, Julian

Gastroenterology (New York, N.Y. 1943), 2020-06, Vol.158 (8), p.2123-2138.e8 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Carbamoyl Pyridone HIV‑1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)
Carbamoyl Pyridone HIV‑1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)
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Carbamoyl Pyridone HIV‑1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Johns, Brian A ; Kawasuji, Takashi ; Weatherhead, Jason G ; Taishi, Teruhiko ; Temelkoff, David P ; Yoshida, Hiroshi ; Akiyama, Toshiyuki ; Taoda, Yoshiyuki ; Murai, Hitoshi ; Kiyama, Ryuichi ; Fuji, Masahiro ; Tanimoto, Norihiko ; Jeffrey, Jerry ; Foster, Scott A ; Yoshinaga, Tomokazu ; Seki, Takahiro ; Kobayashi, Masanori ; Sato, Akihiko ; Johnson, Matthew N ; Garvey, Edward P ; Fujiwara, Tamio

Journal of medicinal chemistry, 2013-07, Vol.56 (14), p.5901-5916 [Periódico revisado por pares]

United States: American Chemical Society

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5
Safety and efficacy of upadacitinib in patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying anti-rheumatic drugs (SELECT-NEXT): a randomised, double-blind, placebo-controlled phase 3 trial
Safety and efficacy of upadacitinib in patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying anti-rheumatic drugs (SELECT-NEXT): a randomised, double-blind, placebo-controlled phase 3 trial
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Safety and efficacy of upadacitinib in patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying anti-rheumatic drugs (SELECT-NEXT): a randomised, double-blind, placebo-controlled phase 3 trial

Burmester, Gerd R ; Kremer, Joel M ; Van den Bosch, Filip ; Kivitz, Alan ; Bessette, Louis ; Li, Yihan ; Zhou, Yijie ; Othman, Ahmed A ; Pangan, Aileen L ; Camp, Heidi S

The Lancet (British edition), 2018-06, Vol.391 (10139), p.2503-2512 [Periódico revisado por pares]

England: Elsevier Ltd

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6
Trial of Upadacitinib and Adalimumab for Psoriatic Arthritis
Trial of Upadacitinib and Adalimumab for Psoriatic Arthritis
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Trial of Upadacitinib and Adalimumab for Psoriatic Arthritis

McInnes, Iain B ; Anderson, Jaclyn K ; Magrey, Marina ; Merola, Joseph F ; Liu, Yi ; Kishimoto, Mitsumasa ; Jeka, Slawomir ; Pacheco-Tena, Cesar ; Wang, Xin ; Chen, Liang ; Zueger, Patrick ; Liu, John ; Pangan, Aileen L ; Behrens, Frank

The New England journal of medicine, 2021-04, Vol.384 (13), p.1227-1239 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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7
Pharmacokinetics, Safety and Tolerability of ABT-494, a Novel Selective JAK 1 Inhibitor, in Healthy Volunteers and Subjects with Rheumatoid Arthritis
Pharmacokinetics, Safety and Tolerability of ABT-494, a Novel Selective JAK 1 Inhibitor, in Healthy Volunteers and Subjects with Rheumatoid Arthritis
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Pharmacokinetics, Safety and Tolerability of ABT-494, a Novel Selective JAK 1 Inhibitor, in Healthy Volunteers and Subjects with Rheumatoid Arthritis

Mohamed, Mohamed-Eslam F. ; Camp, Heidi S. ; Jiang, Ping ; Padley, Robert J. ; Asatryan, Armen ; Othman, Ahmed A.

Clinical pharmacokinetics, 2016-12, Vol.55 (12), p.1547-1558 [Periódico revisado por pares]

Cham: Springer International Publishing

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8
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy
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Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy

Dragovich, Peter S ; Pillow, Thomas H ; Blake, Robert A ; Sadowsky, Jack D ; Adaligil, Emel ; Adhikari, Pragya ; Chen, Jinhua ; Corr, Nicholas ; dela Cruz-Chuh, Josefa ; Del Rosario, Geoffrey ; Fullerton, Aaron ; Hartman, Steven J ; Jiang, Fan ; Kaufman, Susan ; Kleinheinz, Tracy ; Kozak, Katherine R ; Liu, Liling ; Lu, Ying ; Mulvihill, Melinda M ; Murray, Jeremy M ; O’Donohue, Aimee ; Rowntree, Rebecca K ; Sawyer, William S ; Staben, Leanna R ; Wai, John ; Wang, Jian ; Wei, BinQing ; Wei, Wentao ; Xu, Zijin ; Yao, Hui ; Yu, Shang-Fan ; Zhang, Donglu ; Zhang, Hongyan ; Zhang, Shenhua ; Zhao, Yongxin ; Zhou, Hao ; Zhu, Xiaoyu

Journal of medicinal chemistry, 2021-03, Vol.64 (5), p.2576-2607 [Periódico revisado por pares]

United States: American Chemical Society

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9
Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy
Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy
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Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy

Kirtane, Ameya R ; Abouzid, Omar ; Minahan, Daniel ; Bensel, Taylor ; Hill, Alison L ; Selinger, Christian ; Bershteyn, Anna ; Craig, Morgan ; Mo, Shirley S ; Mazdiyasni, Hormoz ; Cleveland, Cody ; Rogner, Jaimie ; Lee, Young-Ah Lucy ; Booth, Lucas ; Javid, Farhad ; Wu, Sarah J ; Grant, Tyler ; Bellinger, Andrew M ; Nikolic, Boris ; Hayward, Alison ; Wood, Lowell ; Eckhoff, Philip A ; Nowak, Martin A ; Langer, Robert ; Traverso, Giovanni

Nature communications, 2018-01, Vol.9 (1), p.2-2, Article 2 [Periódico revisado por pares]

England: Nature Publishing Group

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10
First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
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First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors

YAP, Timothy A ; LI YAN ; RIISNAES, Ruth ; POPE, Lorna L ; HEATON, Simon P ; THOMAS, George ; GARRETT, Michelle D ; SULLIVAN, Daniel M ; DE BONO, Johann S ; TOLCHER, Anthony W ; PATNAIK, Amita ; FEAREN, Ivy ; OLMOS, David ; PAPADOPOULOS, Kyriakos ; BAIRD, Richard D ; DELGADO, Liliana ; TAYLOR, Adekemi ; LUPINACCI, Lisa

Journal of clinical oncology, 2011-12, Vol.29 (35), p.4688-4695 [Periódico revisado por pares]

Alexandria, VA: American Society of Clinical Oncology

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