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1
Viagra (sildenafil citrate) the remarkable story of the discovery and launch
Material Type:
Livro
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Viagra (sildenafil citrate) the remarkable story of the discovery and launch

Larry Katzenstein Eric B Grossman

New York Medical Information Press CMD Publishing c2001

Localização: CQ - Conjunto das Químicas    (616.692 K21v )(Acessar)

2
Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders
Material Type:
Artigo
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Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders

Cisar, Justin S ; Weber, Olivia D ; Clapper, Jason R ; Blankman, Jacqueline L ; Henry, Cassandra L ; Simon, Gabriel M ; Alexander, Jessica P ; Jones, Todd K ; Ezekowitz, R. Alan B ; O’Neill, Gary P ; Grice, Cheryl A

Journal of medicinal chemistry, 2018-10, Vol.61 (20), p.9062-9084 [Periódico revisado por pares]

United States: American Chemical Society

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3
Correction to: Synthesis, Characterization and Antimicrobial Activity of BisPiperazine and its Derivatives: a New Class of Bioactive Molecules with Enhanced Safety and Efficacy
Material Type:
Artigo
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Correction to: Synthesis, Characterization and Antimicrobial Activity of BisPiperazine and its Derivatives: a New Class of Bioactive Molecules with Enhanced Safety and Efficacy

Abbas, Muhammad Azhar ; Aslam, Afeefa ; Iqbal, Mudassir ; Bashir, Sajid ; Mehmood, Tahir ; Kressler, Joerg

Pharmaceutical chemistry journal, 2019-06, Vol.53 (3), p.279 [Periódico revisado por pares]

Springer

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4
The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity
Material Type:
Artigo
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The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity

Canon, Jude ; Rex, Karen ; Saiki, Anne Y ; Mohr, Christopher ; Cooke, Keegan ; Bagal, Dhanashri ; Gaida, Kevin ; Holt, Tyler ; Knutson, Charles G ; Koppada, Neelima ; Lanman, Brian A ; Werner, Jonathan ; Rapaport, Aaron S ; San Miguel, Tisha ; Ortiz, Roberto ; Osgood, Tao ; Sun, Ji-Rong ; Zhu, Xiaochun ; McCarter, John D ; Volak, Laurie P ; Houk, Brett E ; Fakih, Marwan G ; O'Neil, Bert H ; Price, Timothy J ; Falchook, Gerald S ; Desai, Jayesh ; Kuo, James ; Govindan, Ramaswamy ; Hong, David S ; Ouyang, Wenjun ; Henary, Haby ; Arvedson, Tara ; Cee, Victor J ; Lipford, J Russell

Nature (London), 2019-11, Vol.575 (7781), p.217-223 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells
Material Type:
Artigo
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Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells

Zhang, Hangqi ; Li, Ming ; Zhou, Xueming ; Tang, Li ; Chen, Guangying ; Zhang, Yongmin

European journal of medicinal chemistry, 2024-06, Vol.272, p.116497-116497, Article 116497 [Periódico revisado por pares]

France: Elsevier Masson SAS

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6
Design, synthesis, and AChE inhibitory activity of new benzothiazole–piperazines
Material Type:
Artigo
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Design, synthesis, and AChE inhibitory activity of new benzothiazole–piperazines

Demir Özkay, Ümide ; Can, Özgür Devrim ; Sağlık, Begüm Nurpelin ; Acar Çevik, Ulviye ; Levent, Serkan ; Özkay, Yusuf ; Ilgın, Sinem ; Atlı, Özlem

Bioorganic & medicinal chemistry letters, 2016-11, Vol.26 (22), p.5387-5394 [Periódico revisado por pares]

England: Elsevier Ltd

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7
Design, Synthesis, and Antifungal Activity of Acrylamide Derivatives Containing Trifluoromethylpyridine and Piperazine
Material Type:
Artigo
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Design, Synthesis, and Antifungal Activity of Acrylamide Derivatives Containing Trifluoromethylpyridine and Piperazine

Chen, Jinli ; Zhang, Meng ; Yuan, Chunmei ; Zhang, Tao ; Wu, Zhibing ; Li, Tingting ; Chi, Yonggui Robin

Journal of agricultural and food chemistry, 2024-05, Vol.72 (20), p.11360-11368 [Periódico revisado por pares]

United States: American Chemical Society

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8
Sotorasib: First Approval
Material Type:
Artigo
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Sotorasib: First Approval

Blair, Hannah A.

Drugs (New York, N.Y.), 2021-09, Vol.81 (13), p.1573-1579 [Periódico revisado por pares]

Cham: Springer International Publishing

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9
Inhibitors of HIV‑1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir
Material Type:
Artigo
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Inhibitors of HIV‑1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir

Meanwell, Nicholas A ; Krystal, Mark R ; Nowicka-Sans, Beata ; Langley, David R ; Conlon, David A ; Eastgate, Martin D ; Grasela, Dennis M ; Timmins, Peter ; Wang, Tao ; Kadow, John F

Journal of medicinal chemistry, 2018-01, Vol.61 (1), p.62-80 [Periódico revisado por pares]

United States: American Chemical Society

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10
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study
Material Type:
Artigo
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Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study

Larson, Richard A. ; Druker, Brian J. ; Guilhot, Francois ; O'Brien, Stephen G. ; Riviere, Gilles J. ; Krahnke, Tillmann ; Gathmann, Insa ; Wang, Yanfeng

Blood, 2008-04, Vol.111 (8), p.4022-4028 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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