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An oral SARS-CoV-2 M pro inhibitor clinical candidate for the treatment of COVID-19
An oral SARS-CoV-2 M pro inhibitor clinical candidate for the treatment of COVID-19
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An oral SARS-CoV-2 M pro inhibitor clinical candidate for the treatment of COVID-19

Owen, Dafydd R ; Allerton, Charlotte M N ; Anderson, Annaliesa S ; Aschenbrenner, Lisa ; Avery, Melissa ; Berritt, Simon ; Boras, Britton ; Cardin, Rhonda D ; Carlo, Anthony ; Coffman, Karen J ; Dantonio, Alyssa ; Di, Li ; Eng, Heather ; Ferre, RoseAnn ; Gajiwala, Ketan S ; Gibson, Scott A ; Greasley, Samantha E ; Hurst, Brett L ; Kadar, Eugene P ; Kalgutkar, Amit S ; Lee, Jack C ; Lee, Jisun ; Liu, Wei ; Mason, Stephen W ; Noell, Stephen ; Novak, Jonathan J ; Obach, R Scott ; Ogilvie, Kevin ; Patel, Nandini C ; Pettersson, Martin ; Rai, Devendra K ; Reese, Matthew R ; Sammons, Matthew F ; Sathish, Jean G ; Singh, Ravi Shankar P ; Steppan, Claire M ; Stewart, Al E ; Tuttle, Jamison B ; Updyke, Lawrence ; Verhoest, Patrick R ; Wei, Liuqing ; Yang, Qingyi ; Zhu, Yuao

Science (American Association for the Advancement of Science), 2021-12, Vol.374 (6575), p.1586-1593 [Periódico revisado por pares]

United States

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2
Plasma apolipoprotein H limits HCV replication and associates with response to NS3 protease inhibitors-based therapy
Plasma apolipoprotein H limits HCV replication and associates with response to NS3 protease inhibitors-based therapy
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Plasma apolipoprotein H limits HCV replication and associates with response to NS3 protease inhibitors-based therapy

Sultanik, Philippe ; Mallet, Vincent ; Lagaye, Sylvie ; Casrouge, Armanda ; Dorival, Céline ; Barthe, Yoann ; Fontaine, Hélène ; Hézode, Christophe ; Mottez, Estelle ; Bronowicki, Jean-Pierre ; Carrat, Fabrice ; Theodorou, Ioannis ; Abel, Laurent ; Gayat, Etienne ; Fontanet, Arnaud ; Pol, Stanislas ; Albert, Matthew L.

Liver international, 2015-07, Vol.35 (7), p.1833-1844 [Periódico revisado por pares]

United States: Blackwell Publishing Ltd

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3
Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19
Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19
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Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19

Hammond, Jennifer ; Leister-Tebbe, Heidi ; Gardner, Annie ; Abreu, Paula ; Bao, Weihang ; Wisemandle, Wayne ; Baniecki, MaryLynn ; Hendrick, Victoria M ; Damle, Bharat ; Simón-Campos, Abraham ; Pypstra, Rienk ; Rusnak, James M

The New England journal of medicine, 2022-04, Vol.386 (15), p.1397-1408 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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4
Epigenetic scars of CD8 + T cell exhaustion persist after cure of chronic infection in humans
Epigenetic scars of CD8 + T cell exhaustion persist after cure of chronic infection in humans
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Epigenetic scars of CD8 + T cell exhaustion persist after cure of chronic infection in humans

Yates, Kathleen B ; Tonnerre, Pierre ; Martin, Genevieve E ; Gerdemann, Ulrike ; Al Abosy, Rose ; Comstock, Dawn E ; Weiss, Sarah A ; Wolski, David ; Tully, Damien C ; Chung, Raymond T ; Allen, Todd M ; Kim, Arthur Y ; Fidler, Sarah ; Fox, Julie ; Frater, John ; Lauer, Georg M ; Haining, W Nicholas ; Sen, Debattama R

Nature immunology, 2021-08, Vol.22 (8), p.1020-1029 [Periódico revisado por pares]

United States: Nature Publishing Group

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5
Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern
Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern
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Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern

Vangeel, Laura ; Chiu, Winston ; De Jonghe, Steven ; Maes, Piet ; Slechten, Bram ; Raymenants, Joren ; André, Emmanuel ; Leyssen, Pieter ; Neyts, Johan ; Jochmans, Dirk

Antiviral research, 2022-02, Vol.198, p.105252-105252, Article 105252 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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6
EASL Clinical Practice Guidelines: Management of hepatitis C virus infection
EASL Clinical Practice Guidelines: Management of hepatitis C virus infection
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EASL Clinical Practice Guidelines: Management of hepatitis C virus infection

European Association for the Study of the Liver ; European Association for Study of Liver

Journal of hepatology, 2014-02, Vol.60 (2), p.392-420 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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7
Boceprevir for Untreated Chronic HCV Genotype 1 Infection
Boceprevir for Untreated Chronic HCV Genotype 1 Infection
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Boceprevir for Untreated Chronic HCV Genotype 1 Infection

Poordad, Fred ; McCone, Jonathan ; Bacon, Bruce R ; Bruno, Savino ; Manns, Michael P ; Sulkowski, Mark S ; Jacobson, Ira M ; Reddy, K. Rajender ; Goodman, Zachary D ; Boparai, Navdeep ; DiNubile, Mark J ; Sniukiene, Vilma ; Brass, Clifford A ; Albrecht, Janice K ; Bronowicki, Jean-Pierre

The New England journal of medicine, 2011-03, Vol.364 (13), p.1195-1206 [Periódico revisado por pares]

Waltham, MA: Massachusetts Medical Society

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8
Multicenter Study to Transplant Hepatitis C-Infected Kidneys (MYTHIC): An Open-Label Study of Combined Glecaprevir and Pibrentasvir to Treat Recipients of Transplanted Kidneys from Deceased Donors with Hepatitis C Virus Infection
Multicenter Study to Transplant Hepatitis C-Infected Kidneys (MYTHIC): An Open-Label Study of Combined Glecaprevir and Pibrentasvir to Treat Recipients of Transplanted Kidneys from Deceased Donors with Hepatitis C Virus Infection
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Multicenter Study to Transplant Hepatitis C-Infected Kidneys (MYTHIC): An Open-Label Study of Combined Glecaprevir and Pibrentasvir to Treat Recipients of Transplanted Kidneys from Deceased Donors with Hepatitis C Virus Infection

Sise, Meghan E ; Goldberg, David S ; Kort, Jens J ; Schaubel, Douglas E ; Alloway, Rita R ; Durand, Christine M ; Fontana, Robert J ; Brown, Jr, Robert S ; Friedewald, John J ; Prenner, Stacey ; Landis, J Richard ; Fernando, Melissa ; Phillips, Caitlin C ; Woodle, E Steve ; Rike-Shields, Adele ; Sherman, Kenneth E ; Elias, Nahel ; Williams, Winfred W ; Gustafson, Jenna L ; Desai, Niraj M ; Barnaba, Brittany ; Norman, Silas P ; Doshi, Mona ; Sultan, Samuel T ; Aull, Meredith J ; Levitsky, Josh ; Belshe, Dianne S ; Chung, Raymond T ; Reese, Peter P

Journal of the American Society of Nephrology, 2020-11, Vol.31 (11), p.2678-2687 [Periódico revisado por pares]

United States: American Society of Nephrology

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9
Effectiveness of Telaprevir or Boceprevir in Treatment-Experienced Patients With HCV Genotype 1 Infection and Cirrhosis
Effectiveness of Telaprevir or Boceprevir in Treatment-Experienced Patients With HCV Genotype 1 Infection and Cirrhosis
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Effectiveness of Telaprevir or Boceprevir in Treatment-Experienced Patients With HCV Genotype 1 Infection and Cirrhosis

Hézode, Christophe ; Fontaine, Helene ; Dorival, Celine ; Zoulim, Fabien ; Larrey, Dominique ; Canva, Valerie ; De Ledinghen, Victor ; Poynard, Thierry ; Samuel, Didier ; Bourliere, Marc ; Alric, Laurent ; Raabe, Jean–Jacques ; Zarski, Jean–Pierre ; Marcellin, Patrick ; Riachi, Ghassan ; Bernard, Pierre–Henri ; Loustaud–Ratti, Veronique ; Chazouilleres, Olivier ; Abergel, Armand ; Guyader, Dominique ; Metivier, Sophie ; Tran, Albert ; Di Martino, Vincent ; Causse, Xavier ; Dao, Thong ; Lucidarme, Damien ; Portal, Isabelle ; Cacoub, Patrice ; Gournay, Jerome ; Grando–Lemaire, Veronique ; Hillon, Patrick ; Attali, Pierre ; Fontanges, Thierry ; Rosa, Isabelle ; Petrov–Sanchez, Ventzislava ; Barthe, Yoann ; Pawlotsky, Jean–Michel ; Pol, Stanislas ; Carrat, Fabrice ; Bronowicki, Jean–Pierre

Gastroenterology (New York, N.Y. 1943), 2014-07, Vol.147 (1), p.132-142.e4 [Periódico revisado por pares]

United States: Elsevier Inc

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10
Nirmatrelvir Use and Severe Covid-19 Outcomes during the Omicron Surge
Nirmatrelvir Use and Severe Covid-19 Outcomes during the Omicron Surge
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Nirmatrelvir Use and Severe Covid-19 Outcomes during the Omicron Surge

Arbel, Ronen ; Wolff Sagy, Yael ; Hoshen, Moshe ; Battat, Erez ; Lavie, Gil ; Sergienko, Ruslan ; Friger, Michael ; Waxman, Jacob G. ; Dagan, Noa ; Balicer, Ran ; Ben-Shlomo, Yatir ; Peretz, Alon ; Yaron, Shlomit ; Serby, Danielle ; Hammerman, Ariel ; Netzer, Doron

The New England journal of medicine, 2022-09, Vol.387 (9), p.790-798 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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