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Piperazinyl CCR1 antagonists—optimization of human liver microsome stability
Piperazinyl CCR1 antagonists—optimization of human liver microsome stability
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Piperazinyl CCR1 antagonists—optimization of human liver microsome stability

Brown, Matthew F. ; Bahnck, Kevin B. ; Blumberg, Laura C. ; Brissette, William H. ; Burrell, Sara A. ; Driscoll, James P. ; Fedeles, Flavia ; Fisher, Michael B. ; Foti, Robert S. ; Gladue, Ronald P. ; Guzman-Martinez, Aikomari ; Hayward, Matthew M. ; Lira, Paul D. ; Lillie, Brett M. ; Lu, Yi ; Lundquist, Greg D. ; McElroy, Eric B. ; McGlynn, Molly A. ; Paradis, Timothy J. ; Poss, Christopher S. ; Roache, James H. ; Shavnya, Andrei ; Shepard, Richard M. ; Trevena, Kristen A. ; Tylaska, Laurie A.

Bioorganic & medicinal chemistry letters, 2007-06, Vol.17 (11), p.3109-3112 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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2
Essential Role of CCR6 in Directing Activated T Cells to the Skin during Contact Hypersensitivity
Essential Role of CCR6 in Directing Activated T Cells to the Skin during Contact Hypersensitivity
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Essential Role of CCR6 in Directing Activated T Cells to the Skin during Contact Hypersensitivity

Paradis, Timothy J. ; Cole, Susan H. ; Nelson, Robin T. ; Gladue, Ronald P.

Journal of investigative dermatology, 2008-03, Vol.128 (3), p.628-633 [Periódico revisado por pares]

Danvers, MA: Elsevier Inc

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3
CP-481,715, a Potent and Selective CCR1 Antagonist with Potential Therapeutic Implications for Inflammatory Diseases
CP-481,715, a Potent and Selective CCR1 Antagonist with Potential Therapeutic Implications for Inflammatory Diseases
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CP-481,715, a Potent and Selective CCR1 Antagonist with Potential Therapeutic Implications for Inflammatory Diseases

Gladue, Ronald P. ; Tylaska, Laurie A. ; Brissette, William H. ; Lira, Paul D. ; Kath, John C. ; Poss, Christopher S. ; Brown, Matthew F. ; Paradis, Timothy J. ; Conklyn, Maryrose J. ; Ogborne, Kevin T. ; McGlynn, Molly A. ; Lillie, Brett M. ; DiRico, Amy P. ; Mairs, Erin N. ; McElroy, Eric B. ; Martin, William H. ; Stock, Ingrid A. ; Shepard, Richard M. ; Showell, Henry J. ; Neote, Kuldeep

The Journal of biological chemistry, 2003-10, Vol.278 (42), p.40473-40480 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Novel CCR1 antagonists with improved metabolic stability
Novel CCR1 antagonists with improved metabolic stability
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Novel CCR1 antagonists with improved metabolic stability

BROWN, Matthew F ; AVERY, Mike ; LIRA, Paul D ; LILLIE, Brett M ; LUNDQUIST, Greg D ; MAIRS, Erin N ; MCELROY, Eric B ; MCGLYNN, Molly A ; PARADIS, Timothy J ; POSS, Christopher S ; ROSSULEK, Michelle I ; SHEPARD, Richard M ; BRISSETTE, William H ; SIMS, Jeff ; STRELEVITZ, Timothy J ; TRUESDELL, Susan ; TYLASKA, Laurie A ; YOON, Kwansik ; DEYE ZHENG ; CHANG, J. H ; COLIZZA, Kevin ; CONKLYN, Maryrose ; DIRICO, Amy P ; GLADUE, Ronald P ; KATH, John C ; KRUEGER, Suzanne S

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2175-2179 [Periódico revisado por pares]

Oxford: Elsevier

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5
HIV-specific cytotoxic T lymphocytes in seropositive individuals
HIV-specific cytotoxic T lymphocytes in seropositive individuals
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HIV-specific cytotoxic T lymphocytes in seropositive individuals

Walker, Bruce D ; Chakrabarti, Sekhar ; Moss, Bernard ; Paradis, Timothy J ; Flynn, Theresa ; Durno, Amy G ; Blumberg, Richard S ; Kaplan, Joan C ; Hirsch, Martin S ; Schooley, Robert T

Nature (London), 1987-07, Vol.328 (6128), p.345-348 [Periódico revisado por pares]

London: Nature Publishing

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6
Potent small molecule CCR1 antagonists
Potent small molecule CCR1 antagonists
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Potent small molecule CCR1 antagonists

KATH, John C ; BRISSETTE, William H ; MARTIN, William H ; MCELROY, Eric B ; MCGLYNN, Molly A ; PARADIS, Timothy J ; POSS, Christopher S ; STOCK, Ingrid A ; TYLASKA, Laurie A ; DEYE ZHENG ; BROWN, Matthew F ; CONKLYN, Maryrose ; DIRICO, Amy P ; DORFF, Peter ; GLADUE, Ronald P ; LILLIE, Brett M ; LIRA, Paul D ; MAIRS, Erin N

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2169-2173 [Periódico revisado por pares]

Oxford: Elsevier

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7
Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3
Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3
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Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3

Cole, K E ; Strick, C A ; Paradis, T J ; Ogborne, K T ; Loetscher, M ; Gladue, R P ; Lin, W ; Boyd, J G ; Moser, B ; Wood, D E ; Sahagan, B G ; Neote, K

The Journal of experimental medicine, 1998-06, Vol.187 (12), p.2009-2021 [Periódico revisado por pares]

United States: The Rockefeller University Press

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8
HIV-1 Reverse Transcriptase is a Target for Cytotoxic T Lymphocytes in Infected Individuals
HIV-1 Reverse Transcriptase is a Target for Cytotoxic T Lymphocytes in Infected Individuals
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HIV-1 Reverse Transcriptase is a Target for Cytotoxic T Lymphocytes in Infected Individuals

Walker, Bruce D. ; Flexner, Charles ; Paradis, Timothy J. ; Fuller, Thomas C. ; Hirsch, Martin S. ; Schooley, Robert T. ; Moss, Bernard

Science (American Association for the Advancement of Science), 1988-04, Vol.240 (4848), p.64-66 [Periódico revisado por pares]

Washington, DC: The American Association for the Advancement of Science

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9
The anti-tumor activity of anti-CTLA-4 is mediated through its induction of IFN gamma
The anti-tumor activity of anti-CTLA-4 is mediated through its induction of IFN gamma
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The anti-tumor activity of anti-CTLA-4 is mediated through its induction of IFN gamma

Paradis, T J ; Floyd, E ; Burkwit, J ; Cole, S H ; Brunson, B ; Elliott, E ; Gilman, S ; Gladue, R P

Cancer Immunology, Immunotherapy, 2001-05, Vol.50 (3), p.125-133 [Periódico revisado por pares]

Germany: Springer-Verlag

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10
Long-Term Culture and Fine Specificity of Human Cytotoxic T-Lymphocyte Clones Reactive with Human Immunodeficiency Virus Type 1
Long-Term Culture and Fine Specificity of Human Cytotoxic T-Lymphocyte Clones Reactive with Human Immunodeficiency Virus Type 1
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Long-Term Culture and Fine Specificity of Human Cytotoxic T-Lymphocyte Clones Reactive with Human Immunodeficiency Virus Type 1

Walker, Bruce D. ; Flexner, Charles ; Birch-Limberger, Karen ; Fisher, Laura ; Paradis, Timothy J. ; Aldovini, Anna ; Young, Richard ; Moss, Bernard ; Schooley, Robert T.

Proceedings of the National Academy of Sciences - PNAS, 1989-12, Vol.86 (23), p.9514-9518 [Periódico revisado por pares]

Washington, DC: National Academy of Sciences of the United States of America

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