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Material Type: Artigo
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Mitochondrial quality control turns out to be the principal suspect in parkin and PINK1-related autosomal recessive Parkinson's disease: Mitochondrial quality control mechanismsCorti, Olga ; Brice, AlexisCurrent opinion in neurobiology, 2013-02, Vol.23 (1), p.100-108 [Periódico revisado por pares]ElsevierTexto completo disponível |
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Material Type: Artigo
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Adaptor linked K63 di-ubiquitin activates Nedd4/Rsp5 E3 ligaseZhu, Lu ; Zhang, Qing ; Cordeiro, Ciro D ; Banjade, Sudeep ; Sardana, Richa ; Mao, Yuxin ; Emr, Scott DeLife, 2022-06, Vol.11 [Periódico revisado por pares]England: eLife Science Publications, LtdTexto completo disponível |
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E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3Gao, Peng ; Ma, Xianwei ; Yuan, Ming ; Yi, Yulan ; Liu, Guoke ; Wen, Mingyue ; Jiang, Wei ; Ji, Ruihua ; Zhu, Lingxi ; Tang, Zhen ; Yu, Qingzhuo ; Xu, Jing ; Yang, Rui ; Xia, Sheng ; Yang, Mingjin ; Pan, Jianping ; Yuan, Hongbin ; An, HuazhangNature communications, 2021-02, Vol.12 (1), p.1194-1194, Article 1194 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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TRIM5 is an innate immune sensor for the retrovirus capsid latticePERTEL, Thomas ; HAUSMANN, Stéphane ; BISIAUX, Aurélie ; ALBERT, Matthew L ; STRAMBIO-DE-CASTILLIA, Caterina ; MOTHES, Walther ; PIZZATO, Massimo ; GRÜTTER, Markus G ; LUBAN, Jeremy ; MORGER, Damien ; ZÜGER, Sara ; GUERRA, Jessica ; LASCANO, Josefina ; REINHARD, Christian ; SANTONI, Federico A ; UCHIL, Pradeep D ; CHATEL, LaurenceNature (London), 2011-04, Vol.472 (7343), p.361-365 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Allosteric auto‐inhibition and activation of the Nedd4 family E3 ligase ItchZhu, Kang ; Shan, Zelin ; Chen, Xing ; Cai, Yuqun ; Cui, Lei ; Yao, Weiyi ; Wang, Zhen ; Shi, Pan ; Tian, Changlin ; Lou, Jizhong ; Xie, Yunli ; Wen, WenyuEMBO reports, 2017-09, Vol.18 (9), p.1618-1630 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant ProbesZhang, Wei ; Wu, Kuen-Phon ; Sartori, Maria A. ; Kamadurai, Hari B. ; Ordureau, Alban ; Jiang, Chong ; Mercredi, Peter Y. ; Murchie, Ryan ; Hu, Jicheng ; Persaud, Avinash ; Mukherjee, Manjeet ; Li, Nan ; Doye, Anne ; Walker, John R. ; Sheng, Yi ; Hao, Zhenyue ; Li, Yanjun ; Brown, Kevin R. ; Lemichez, Emmanuel ; Chen, Junjie ; Tong, Yufeng ; Harper, J. Wade ; Moffat, Jason ; Rotin, Daniela ; Schulman, Brenda A. ; Sidhu, Sachdev S.Molecular cell, 2016-04, Vol.62 (1), p.121-136 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligasesWang, Zhen ; Liu, Ziheng ; Chen, Xing ; Li, Jingyu ; Yao, Weiyi ; Huang, Shijing ; Gu, Aihong ; Lei, Qun-Ying ; Mao, Ying ; Wen, WenyuNature communications, 2019-07, Vol.10 (1), p.3162-15, Article 3162 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Inhibition of HECT E3 ligases as potential therapy for COVID-19Novelli, Giuseppe ; Liu, Jing ; Biancolella, Michela ; Alonzi, Tonino ; Novelli, Antonio ; Patten, J J ; Cocciadiferro, Dario ; Agolini, Emanuele ; Colona, Vito Luigi ; Rizzacasa, Barbara ; Giannini, Rosalinda ; Bigio, Benedetta ; Goletti, Delia ; Capobianchi, Maria Rosaria ; Grelli, Sandro ; Mann, Justin ; McKee, Trevor D ; Cheng, Ke ; Amanat, Fatima ; Krammer, Florian ; Guarracino, Andrea ; Pepe, Gerardo ; Tomino, Carlo ; Tandjaoui-Lambiotte, Yacine ; Uzunhan, Yurdagul ; Tubiana, Sarah ; Ghosn, Jade ; Notarangelo, Luigi D ; Su, Helen C ; Abel, Laurent ; Cobat, Aurélie ; Elhanan, Gai ; Grzymski, Joseph J ; Latini, Andrea ; Sidhu, Sachdev S ; Jain, Suresh ; Davey, Robert A ; Casanova, Jean-Laurent ; Wei, Wenyi ; Pandolfi, Pier PaoloCell death & disease, 2021-03, Vol.12 (4), p.310-310, Article 310 [Periódico revisado por pares]England: Springer Nature B.VTexto completo disponível |
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Material Type: Artigo
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Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stressFang, Nancy N ; Chan, Gerard T ; Zhu, Mang ; Comyn, Sophie A ; Persaud, Avinash ; Deshaies, Raymond J ; Rotin, Daniela ; Gsponer, Joerg ; Mayor, ThibaultNature cell biology, 2014-12, Vol.16 (12), p.1227-1237 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signalingChen, Huimei ; Moreno-Moral, Aida ; Pesce, Francesco ; Devapragash, Nithya ; Mancini, Massimiliano ; Heng, Ee Ling ; Rotival, Maxime ; Srivastava, Prashant K ; Harmston, Nathan ; Shkura, Kirill ; Rackham, Owen J L ; Yu, Wei-Ping ; Sun, Xi-Ming ; Tee, Nicole Gui Zhen ; Tan, Elisabeth Li Sa ; Barton, Paul J R ; Felkin, Leanne E ; Lara-Pezzi, Enrique ; Angelini, Gianni ; Beltrami, Cristina ; Pravenec, Michal ; Schafer, Sebastian ; Bottolo, Leonardo ; Hubner, Norbert ; Emanueli, Costanza ; Cook, Stuart A ; Petretto, EnricoNature communications, 2019-08, Vol.10 (1), p.3616-19, Article 3616 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |