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Redox homeostasis maintained by GPX4 facilitates STING activation
Redox homeostasis maintained by GPX4 facilitates STING activation
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Redox homeostasis maintained by GPX4 facilitates STING activation

Jia, Mutian ; Qin, Danhui ; Zhao, Chunyuan ; Chai, Li ; Yu, Zhongxia ; Wang, Wenwen ; Tong, Li ; Lv, Lin ; Wang, Yuanyuan ; Rehwinkel, Jan ; Yu, Jinming ; Zhao, Wei

Nature immunology, 2020-07, Vol.21 (7), p.727-735 [Periódico revisado por pares]

United States: Nature Publishing Group

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2
Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer
Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer
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Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer

Ghoochani, Ali ; Hsu, En-Chi ; Aslan, Merve ; Rice, Meghan A ; Nguyen, Holly M ; Brooks, James D ; Corey, Eva ; Paulmurugan, Ramasamy ; Stoyanova, Tanya

Cancer research (Chicago, Ill.), 2021-03, Vol.81 (6), p.1583-1594 [Periódico revisado por pares]

United States

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3
Action of MK‐7264 (gefapixant) at human P2X3 and P2X2/3 receptors and in vivo efficacy in models of sensitisation
Action of MK‐7264 (gefapixant) at human P2X3 and P2X2/3 receptors and in vivo efficacy in models of sensitisation
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Action of MK‐7264 (gefapixant) at human P2X3 and P2X2/3 receptors and in vivo efficacy in models of sensitisation

Richards, David ; Gever, Joel R. ; Ford, Anthony P. ; Fountain, Samuel J.

British journal of pharmacology, 2019-07, Vol.176 (13), p.2279-2291 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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4
Current development of β-carboline derived potential antimalarial scaffolds
Current development of β-carboline derived potential antimalarial scaffolds
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Current development of β-carboline derived potential antimalarial scaffolds

Kushwaha, Preeti ; Kumar, Vipin ; Saha, Biswajit

European journal of medicinal chemistry, 2023-04, Vol.252, p.115247-115247, Article 115247 [Periódico revisado por pares]

France: Elsevier Masson SAS

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5
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
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Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers

Soula, Mariluz ; Weber, Ross A ; Zilka, Omkar ; Alwaseem, Hanan ; La, Konnor ; Yen, Frederick ; Molina, Henrik ; Garcia-Bermudez, Javier ; Pratt, Derek A ; Birsoy, Kıvanç

Nature chemical biology, 2020-12, Vol.16 (12), p.1351-1360 [Periódico revisado por pares]

United States: Nature Publishing Group

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6
Recent insights into synthetic β-carbolines with anti-cancer activities
Recent insights into synthetic β-carbolines with anti-cancer activities
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Recent insights into synthetic β-carbolines with anti-cancer activities

Kumar, Sumit ; Singh, Amandeep ; Kumar, Kewal ; Kumar, Vipan

European journal of medicinal chemistry, 2017-12, Vol.142, p.48-73 [Periódico revisado por pares]

France: Elsevier Masson SAS

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7
Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria
Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria
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Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria

Yeung, Bryan K. S ; Zou, Bin ; Rottmann, Matthias ; Lakshminarayana, Suresh B ; Ang, Shi Hua ; Leong, Seh Yong ; Tan, Jocelyn ; Wong, Josephine ; Keller-Maerki, Sonja ; Fischli, Christoph ; Goh, Anne ; Schmitt, Esther K ; Krastel, Philipp ; Francotte, Eric ; Kuhen, Kelli ; Plouffe, David ; Henson, Kerstin ; Wagner, Trixie ; Winzeler, Elizabeth A ; Petersen, Frank ; Brun, Reto ; Dartois, Veronique ; Diagana, Thierry T ; Keller, Thomas H

Journal of medicinal chemistry, 2010-07, Vol.53 (14), p.5155-5164 [Periódico revisado por pares]

United States: American Chemical Society

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8
Regulation of Ferroptotic Cancer Cell Death by GPX4
Regulation of Ferroptotic Cancer Cell Death by GPX4
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Regulation of Ferroptotic Cancer Cell Death by GPX4

Yang, Wan Seok ; SriRamaratnam, Rohitha ; Welsch, Matthew E. ; Shimada, Kenichi ; Skouta, Rachid ; Viswanathan, Vasanthi S. ; Cheah, Jaime H. ; Clemons, Paul A. ; Shamji, Alykhan F. ; Clish, Clary B. ; Brown, Lewis M. ; Girotti, Albert W. ; Cornish, Virginia W. ; Schreiber, Stuart L. ; Stockwell, Brent R.

Cell, 2014-01, Vol.156 (1-2), p.317-331 [Periódico revisado por pares]

United States: Elsevier Inc

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9
Ayahuasca: pharmacology, neuroscience and therapeutic potential
Ayahuasca: pharmacology, neuroscience and therapeutic potential
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Ayahuasca: pharmacology, neuroscience and therapeutic potential

Domínguez-Clavé, Elisabet ; Soler, Joaquim ; Elices, Matilde ; Pascual, Juan C ; Álvarez, Enrique ; Revenga, Mario de la Fuente ; Friedlander, Pablo ; Feilding, Amanda ; Riba, Jordi

Brain research bulletin, 2016-09, Vol.126 (Pt 1), p.89-101 [Periódico revisado por pares]

United States: Elsevier Inc

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10
Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer
Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer
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Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer

Yang, Jiawen ; Mo, Jiajie ; Dai, Juji ; Ye, Chenqiao ; Cen, Wei ; Zheng, Xuzhi ; Jiang, Lei ; Ye, Lechi

Cell death & disease, 2021-11, Vol.12 (11), p.1079-1079, Article 1079 [Periódico revisado por pares]

England: Springer Nature B.V

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