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Material Type: Artigo
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Triple-Negative Breast Cancer Risk Genes Identified by Multigene Hereditary Cancer Panel TestingShimelis, Hermela ; LaDuca, Holly ; Hu, Chunling ; Hart, Steven N ; Na, Jie ; Thomas, Abigail ; Akinhanmi, Margaret ; Moore, Raymond M ; Brauch, Hiltrud ; Cox, Angela ; Eccles, Diana M ; Ewart-Toland, Amanda ; Fasching, Peter A ; Fostira, Florentia ; Garber, Judy ; Godwin, Andrew K ; Konstantopoulou, Irene ; Nevanlinna, Heli ; Sharma, Priyanka ; Yannoukakos, Drakoulis ; Yao, Song ; Feng, Bing-Jian ; Tippin Davis, Brigette ; Lilyquist, Jenna ; Pesaran, Tina ; Goldgar, David E ; Polley, Eric C ; Dolinsky, Jill S ; Couch, Fergus JJNCI : Journal of the National Cancer Institute, 2018-08, Vol.110 (8), p.855-862 [Periódico revisado por pares]United States: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Cross‐Ancestry Genome‐Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma ConcentrationsKhor, Chiea Chuen ; Winter, Stefan ; Sutiman, Natalia ; Mürdter, Thomas E. ; Chen, Sylvia ; Lim, Joanne Siok Liu ; Li, Zheng ; Li, Jingmei ; Sim, Kar Seng ; Ganchev, Boian ; Eccles, Diana ; Eccles, Bryony ; Tapper, William ; Zgheib, Nathalie K. ; Tfayli, Arafat ; Ng, Raymond Chee Hui ; Yap, Yoon Sim ; Lim, Elaine ; Wong, Mabel ; Wong, Nan Soon ; Ang, Peter Cher Siang ; Dent, Rebecca ; Tremmel, Roman ; Klein, Kathrin ; Schaeffeler, Elke ; Zhou, Yitian ; Lauschke, Volker M. ; Eichelbaum, Michel ; Schwab, Matthias ; Brauch, Hiltrud B. ; Chowbay, Balram ; Schroth, WernerClinical pharmacology and therapeutics, 2023-03, Vol.113 (3), p.712-723 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Breast Cancer Treatment Outcome With Adjuvant Tamoxifen Relative to Patient CYP2D6 and CYP2C19 GenotypesSCHROTH, Werner ; ANTONIADOU, Lydia ; FRITZ, Peter ; SCHWAB, Matthias ; MUERDTER, Thomas ; ZANGER, Ulrich M ; SIMON, Wolfgang ; EICHELBAUM, Michel ; BRAUCH, HiltrudJournal of clinical oncology, 2007-11, Vol.25 (33), p.5187-5193 [Periódico revisado por pares]Baltimore, MD: American Society of Clinical OncologySem texto completo |
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Material Type: Artigo
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A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk FactorsFILIPITS, Martin ; RUDAS, Margaretha ; FREIBAUER, Christa ; MÜLLER, Volkmar ; JÄNICKE, Fritz ; SCHMIDT, Marcus ; KÖLBL, Heinz ; RODY, Achim ; KAUFMANN, Manfred ; SCHROTH, Werner ; BRAUCH, Hiltrud ; SCHWAB, Matthias ; JAKESZ, Raimund ; FRITZ, Peter ; WEBER, Karsten E ; FEDER, Inke S ; HENNIG, Guido ; KRONENWETT, Ralf ; GEHRMANN, Mathias ; GNANT, Michael ; DUBSKY, Peter ; FITZAL, Florian ; SINGER, Christian F ; DIETZE, Otto ; GREIL, Richard ; JELEN, Andrea ; SEVELDA, PaulClinical cancer research, 2011-09, Vol.17 (18), p.6012-6020 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Gene Expression Signatures of BRCAness and Tumor Inflammation Define Subgroups of Early-Stage Hormone Receptor-Positive Breast Cancer PatientsSchroth, Werner ; Büttner, Florian A ; Kandabarau, Siarhei ; Hoppe, Reiner ; Fritz, Peter ; Kumbrink, Jörg ; Kirchner, Thomas ; Brauer, Heather A ; Ren, Yuqi ; Henderson, David ; Madden, Stephen F ; Sauer, Georg ; Fehm, Tanja ; Wallwiener, Diethelm ; Fasching, Peter A ; Mürdter, Thomas ; Schwab, Matthias ; Brauch, HiltrudClinical cancer research, 2020-12, Vol.26 (24), p.6523-6534 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Pharmacogenomics of Tamoxifen TherapyBrauch, Hiltrud ; Murdter, Thomas E ; Eichelbaum, Michel ; Schwab, MatthiasClinical chemistry (Baltimore, Md.), 2009-10, Vol.55 (10), p.1770-1782 [Periódico revisado por pares]Washington, DC: Am Assoc Clin ChemTexto completo disponível |
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Material Type: Artigo
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Cytokines-activated nuclear IKKα-FAT10 pathway induces breast cancer tamoxifen-resistanceChen, Xueyan ; Wu, Weilin ; Jeong, Ji-Hak ; Rokavec, Matjaz ; Wei, Rui ; Feng, Shaolong ; Schroth, Werner ; Brauch, Hiltrud ; Zhong, Shangwei ; Luo, Jun-LiScience China. Life sciences, 2024-07, Vol.67 (7), p.1413-1426 [Periódico revisado por pares]Beijing: Science China PressTexto completo disponível |
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Material Type: Artigo
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Improved Prediction of Endoxifen Metabolism by CYP2D6 Genotype in Breast Cancer Patients Treated with TamoxifenSchroth, Werner ; Winter, Stefan ; Mürdter, Thomas ; Schaeffeler, Elke ; Eccles, Diana ; Eccles, Bryony ; Chowbay, Balram ; Khor, Chiea C ; Tfayli, Arafat ; Zgheib, Nathalie K ; Eichelbaum, Michel ; Schwab, Matthias ; Brauch, HiltrudFrontiers in pharmacology, 2017-08, Vol.8, p.582 [Periódico revisado por pares]Switzerland: Frontiers Media S.ATexto completo disponível |
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Material Type: Artigo
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Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulationKonduri, Santhi D. ; Medisetty, Rajesh ; Liu, Wensheng ; Kaipparettu, Benny Abraham ; Srivastava, Pratima ; Brauch, Hiltrud ; Fritz, Peter ; Swetzig, Wendy M. ; Gardner, Amanda E. ; Khan, Sohaib A. ; Das, Gokul M. ; Jensen, Elwood V.Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (34), p.15081-15086 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studiesGoetz, Matthew P ; Sun, James X ; Suman, Vera J ; Silva, Grace O ; Perou, Charles M ; Nakamura, Yusuke ; Cox, Nancy J ; Stephens, Philip J ; Miller, Vincent A ; Ross, Jeffrey S ; Chen, David ; Safgren, Stephanie L ; Kuffel, Mary J ; Ames, Matthew M ; Kalari, Krishna R ; Gomez, Henry L ; Gonzalez-Angulo, Ana M ; Burgues, Octavio ; Brauch, Hiltrud B ; Ingle, James N ; Ratain, Mark J ; Yelensky, RomanJNCI : Journal of the National Cancer Institute, 2015-02, Vol.107 (2), p.1 [Periódico revisado por pares]United States: Oxford Publishing Limited (England)Texto completo disponível |