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Material Type: Artigo
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FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formationHu, Jun Jacob ; Liu, Xing ; Xia, Shiyu ; Zhang, Zhibin ; Zhang, Ying ; Zhao, Jingxia ; Ruan, Jianbin ; Luo, Xuemei ; Lou, Xiwen ; Bai, Yang ; Wang, Junhong ; Hollingsworth, L Robert ; Magupalli, Venkat Giri ; Zhao, Li ; Luo, Hongbo R ; Kim, Justin ; Lieberman, Judy ; Wu, HaoNature immunology, 2020-07, Vol.21 (7), p.736-745 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAsZheng, Qiupeng ; Bao, Chunyang ; Guo, Weijie ; Li, Shuyi ; Chen, Jie ; Chen, Bing ; Luo, Yanting ; Lyu, Dongbin ; Li, Yan ; Shi, Guohai ; Liang, Linhui ; Gu, Jianren ; He, Xianghuo ; Huang, ShenglinNature communications, 2016-04, Vol.7 (1), p.11215-11215, Article 11215 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 SubstratesEgan, Daniel F. ; Chun, Matthew G.H. ; Vamos, Mitchell ; Zou, Haixia ; Rong, Juan ; Miller, Chad J. ; Lou, Hua Jane ; Raveendra-Panickar, Dhanya ; Yang, Chih-Cheng ; Sheffler, Douglas J. ; Teriete, Peter ; Asara, John M. ; Turk, Benjamin E. ; Cosford, Nicholas D.P. ; Shaw, Reuben J.Molecular cell, 2015-07, Vol.59 (2), p.285-297 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Dying cells fan the flames of inflammationNewton, Kim ; Dixit, Vishva M ; Kayagaki, NobuhikoScience (American Association for the Advancement of Science), 2021-11, Vol.374 (6571), p.1076-1080 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formationSilva, Camila Meirelles S. ; Wanderley, Carlos Wagner S. ; Veras, Flavio P. ; Sonego, Fabiane ; Nascimento, Daniele C. ; Gonçalves, Augusto V. ; Martins, Timna V. ; Cólon, David F. ; Borges, Vanessa F. ; Brauer, Verônica S. ; Damasceno, Luis Eduardo A. ; Silva, Katiussia P. ; Toller-Kawahisa, Juliana E. ; Batah, Sabrina S. ; Souza, Ana Letícia J. ; Monteiro, Valter S. ; Oliveira, Antônio Edson R. ; Donate, Paula B. ; Zoppi, Daniel ; Borges, Marcos C. ; Almeida, Fausto ; Nakaya, Helder I. ; Fabro, Alexandre T. ; Cunha, Thiago M. ; Alves-Filho, José Carlos ; Zamboni, Dario S. ; Cunha, Fernando Q.Blood, 2021-12, Vol.138 (25), p.2702-2713 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Nuclear cGAS suppresses DNA repair and promotes tumorigenesisLiu, Haipeng ; Zhang, Haiping ; Wu, Xiangyang ; Ma, Dapeng ; Wu, Juehui ; Wang, Lin ; Jiang, Yan ; Fei, Yiyan ; Zhu, Chenggang ; Tan, Rong ; Jungblut, Peter ; Pei, Gang ; Dorhoi, Anca ; Yan, Qiaoling ; Zhang, Fan ; Zheng, Ruijuan ; Liu, Siyu ; Liang, Haijiao ; Liu, Zhonghua ; Yang, Hua ; Chen, Jianxia ; Wang, Peng ; Tang, Tianqi ; Peng, Wenxia ; Hu, Zhangsen ; Xu, Zhu ; Huang, Xiaochen ; Wang, Jie ; Li, Haohao ; Zhou, Yilong ; Liu, Feng ; Yan, Dapeng ; Kaufmann, Stefan H E ; Chen, Chang ; Mao, Zhiyong ; Ge, BaoxueNature (London), 2018-11, Vol.563 (7729), p.131-136 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathwayChen, Zhen-Hua ; Wang, Wen-Tao ; Huang, Wei ; Fang, Ke ; Sun, Yu-Meng ; Liu, Shu-Rong ; Luo, Xue-Qun ; Chen, Yue-QinCell death and differentiation, 2017-02, Vol.24 (2), p.212-224 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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MK2 phosphorylation of RIPK1 regulates TNF-mediated cell deathDondelinger, Yves ; Delanghe, Tom ; Rojas-Rivera, Diego ; Priem, Dario ; Delvaeye, Tinneke ; Bruggeman, Inge ; Van Herreweghe, Franky ; Vandenabeele, Peter ; Bertrand, Mathieu J MNature cell biology, 2017-10, Vol.19 (10), p.1237-1247 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Crosstalk between hepatic tumor cells and macrophages via Wnt/β-catenin signaling promotes M2-like macrophage polarization and reinforces tumor malignant behaviorsYang, Yang ; Ye, Yu-Chen ; Chen, Yan ; Zhao, Jun-Long ; Gao, Chun-Chen ; Han, Hua ; Liu, Wen-Chao ; Qin, Hong-YanCell death & disease, 2018-07, Vol.9 (8), p.793-14, Article 793 [Periódico revisado por pares]England: Springer Nature B.VTexto completo disponível |
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Material Type: Artigo
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Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)Rathore, Rama ; McCallum, Jennifer E. ; Varghese, Elizabeth ; Florea, Ana-Maria ; Büsselberg, DietrichApoptosis (London), 2017-07, Vol.22 (7), p.898-919 [Periódico revisado por pares]New York: Springer USTexto completo disponível |