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Conformational analysis of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione (rogletimide) and discovery of potent 5-alkyl derivatives
Conformational analysis of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione (rogletimide) and discovery of potent 5-alkyl derivatives
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Conformational analysis of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione (rogletimide) and discovery of potent 5-alkyl derivatives

McCague, Raymond ; Rowlands, Martin G

Journal of medicinal chemistry, 1992-10, Vol.35 (20), p.3699-3704 [Periódico revisado por pares]

WASHINGTON: American Chemical Society

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2
Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions
Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions
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Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions

Rodgers, Trudy ; Rowland, Malcolm

Journal of pharmaceutical sciences, 2006-06, Vol.95 (6), p.1238-1257 [Periódico revisado por pares]

Hoboken: Elsevier Inc

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3
Analogs of aminoglutethimide: selective inhibition of aromatase
Analogs of aminoglutethimide: selective inhibition of aromatase
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Analogs of aminoglutethimide: selective inhibition of aromatase

Foster, Allan B ; Jarman, Michael ; Leung, Chui Sheung ; Rowlands, Martin G ; Taylor, Grahame N

Journal of medicinal chemistry, 1985-02, Vol.28 (2), p.200-204 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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4
Inhibition of enzymes of estrogen and androgen biosynthesis by esters of 4-pyridylacetic acid
Inhibition of enzymes of estrogen and androgen biosynthesis by esters of 4-pyridylacetic acid
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Inhibition of enzymes of estrogen and androgen biosynthesis by esters of 4-pyridylacetic acid

McCague, Raymond ; Rowlands, Martin G ; Barrie, S. Elaine ; Houghton, John

Journal of medicinal chemistry, 1990-11, Vol.33 (11), p.3050-3055 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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5
Rationally Designed Analogs of Tamoxifen with Improved Calmodulin Antagonism
Rationally Designed Analogs of Tamoxifen with Improved Calmodulin Antagonism
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Rationally Designed Analogs of Tamoxifen with Improved Calmodulin Antagonism

Hardcastle, Ian R ; Rowlands, Martin G ; Houghton, John ; Parr, Iris B ; Potter, Gerard A ; Jarman, Michael ; Edwards, Karen J ; Laughton, Charles A ; Trent, John O ; Neidle, Stephen

Journal of medicinal chemistry, 1995-01, Vol.38 (2), p.241-248 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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6
The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors
The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors
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The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors

Cheung, Kwai-Ming J. ; Matthews, Thomas P. ; James, Karen ; Rowlands, Martin G. ; Boxall, Katherine J. ; Sharp, Swee Y. ; Maloney, Alison ; Roe, S. Mark ; Prodromou, Chrisostomos ; Pearl, Laurence H. ; Aherne, G. Wynne ; McDonald, Edward ; Workman, Paul

Bioorganic & medicinal chemistry letters, 2005-07, Vol.15 (14), p.3338-3343 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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7
Homologs of Idoxifene:  Variation of Estrogen Receptor Binding and Calmodulin Antagonism with Chain Length
Homologs of Idoxifene:  Variation of Estrogen Receptor Binding and Calmodulin Antagonism with Chain Length
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Homologs of Idoxifene:  Variation of Estrogen Receptor Binding and Calmodulin Antagonism with Chain Length

Hardcastle, Ian R ; Rowlands, Martin G ; Grimshaw, Rachel M ; Houghton, John ; Jarman, Michael ; Sharff, Andrew ; Neidle, Stephen

Journal of medicinal chemistry, 1996-02, Vol.39 (4), p.999-1004 [Periódico revisado por pares]

United States: American Chemical Society

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8
Tissue Distribution of Basic Drugs: Accounting for Enantiomeric, Compound and Regional Differences Amongst β-Blocking Drugs in Rat
Tissue Distribution of Basic Drugs: Accounting for Enantiomeric, Compound and Regional Differences Amongst β-Blocking Drugs in Rat
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Tissue Distribution of Basic Drugs: Accounting for Enantiomeric, Compound and Regional Differences Amongst β-Blocking Drugs in Rat

Rodgers, Trudy ; Leahy, David ; Rowland, Malcolm

Journal of pharmaceutical sciences, 2005-06, Vol.94 (6), p.1237-1248 [Periódico revisado por pares]

Hoboken: Elsevier Inc

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9
Analogs of 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione as selective inhibitors of aromatase: derivatives with variable 1-alkyl and 3-alkyl substituents
Analogs of 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione as selective inhibitors of aromatase: derivatives with variable 1-alkyl and 3-alkyl substituents
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Analogs of 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione as selective inhibitors of aromatase: derivatives with variable 1-alkyl and 3-alkyl substituents

Leung, Chui Sheung ; Rowlands, Martin G. ; Jarman, Michael ; Foster, Allan B. ; Griggs, Leslie J. ; Wilman, Derry E. V.

Journal of medicinal chemistry, 1987-09, Vol.30 (9), p.1550-1554 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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10
Analogs of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity
Analogs of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity
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Analogs of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity

Rowlands, Martin G ; Bunnett, Michael A ; Foster, Allan B ; Jarman, Michael ; Stanek, Jaroslav ; Schweizer, Ernst

Journal of medicinal chemistry, 1988-05, Vol.31 (5), p.971-976 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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