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1 |
Material Type: Artigo
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Impaired Presynaptic High-Affinity Choline Transporter Causes a Congenital Myasthenic Syndrome with Episodic ApneaBauché, Stéphanie ; O’Regan, Seana ; Azuma, Yoshiteru ; Laffargue, Fanny ; McMacken, Grace ; Sternberg, Damien ; Brochier, Guy ; Buon, Céline ; Bouzidi, Nassima ; Topf, Ana ; Lacène, Emmanuelle ; Remerand, Ganaelle ; Beaufrere, Anne-Marie ; Pebrel-Richard, Céline ; Thevenon, Julien ; El Chehadeh-Djebbar, Salima ; Faivre, Laurence ; Duffourd, Yannis ; Ricci, Federica ; Mongini, Tiziana ; Fiorillo, Chiara ; Astrea, Guja ; Burloiu, Carmen Magdalena ; Butoianu, Niculina ; Sandu, Carmen ; Servais, Laurent ; Bonne, Gisèle ; Nelson, Isabelle ; Desguerre, Isabelle ; Nougues, Marie-Christine ; Bœuf, Benoit ; Romero, Norma ; Laporte, Jocelyn ; Boland, Anne ; Lechner, Doris ; Deleuze, Jean-François ; Fontaine, Bertrand ; Strochlic, Laure ; Lochmuller, Hanns ; Eymard, Bruno ; Mayer, Michèle ; Nicole, SophieAmerican journal of human genetics, 2016-09, Vol.99 (3), p.753-761 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Review of human butyrylcholinesterase structure, function, genetic variants, history of use in the clinic, and potential therapeutic usesLockridge, OksanaPharmacology & therapeutics (Oxford), 2015-04, Vol.148, p.34-46 [Periódico revisado por pares]EnglandTexto completo disponível |
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Material Type: Artigo
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Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesteraseNachon, Florian ; Carletti, Eugénie ; Ronco, Cyril ; Trovaslet, Marie ; Nicolet, Yvain ; Jean, Ludovic ; Renard, Pierre-YvesBiochemical journal, 2013-08, Vol.453 (3), p.393-399 [Periódico revisado por pares]England: Portland PressTexto completo disponível |
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Material Type: Artigo
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Combined Quantum Mechanics/Molecular Mechanics (QM/MM) Methods in Computational Enzymologyvan der Kamp, Marc W ; Mulholland, Adrian JBiochemistry (Easton), 2013-04, Vol.52 (16), p.2708-2728 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Butyrylcholinesterase-knockout reduces brain deposition of fibrillar β-amyloid in an Alzheimer mouse modelReid, G. Andrew ; Darvesh, SultanNeuroscience, 2015-07, Vol.298, p.424-435 [Periódico revisado por pares]United States: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and α-glucosidase inhibitorsTürkeş, Cüneyt ; Akocak, Suleyman ; Işık, Mesut ; Lolak, Nebih ; Taslimi, Parham ; Durgun, Mustafa ; Gülçin, İlhami ; Budak, Yakup ; Beydemir, ŞükrüJournal of biomolecular structure & dynamics, 2022-01, Vol.40 (19), p.8752-8764 [Periódico revisado por pares]England: Taylor & FrancisTexto completo disponível |
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Material Type: Artigo
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Resurrection and Reactivation of Acetylcholinesterase and ButyrylcholinesteraseFranjesevic, Andrew J. ; Sillart, Sydney B. ; Beck, Jeremy M. ; Vyas, Shubham ; Callam, Christopher S. ; Hadad, Christopher M.Chemistry : a European journal, 2019-04, Vol.25 (21), p.5337-5371 [Periódico revisado por pares]Germany: Wiley Subscription Services, IncTexto completo disponível |
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Material Type: Artigo
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Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer’s DiseaseRossi, Michele ; Freschi, Michela ; de Camargo Nascente, Luciana ; Salerno, Alessandra ; de Melo Viana Teixeira, Sarah ; Nachon, Florian ; Chantegreil, Fabien ; Soukup, Ondrej ; Prchal, Lukáš ; Malaguti, Marco ; Bergamini, Christian ; Bartolini, Manuela ; Angeloni, Cristina ; Hrelia, Silvana ; Soares Romeiro, Luiz Antonio ; Bolognesi, Maria LauraJournal of medicinal chemistry, 2021-04, Vol.64 (8), p.4972-4990 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Cholinesterases and the fine line between poison and remedyPope, Carey N. ; Brimijoin, StephenBiochemical pharmacology, 2018-07, Vol.153, p.205-216 [Periódico revisado por pares]England: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's diseaseLiu, Dan ; Zhang, Honghua ; Wang, Yuying ; Liu, Wencheng ; Yin, Gaofeng ; Wang, Degui ; Li, Junfang ; Shi, Tao ; Wang, ZhenEuropean journal of medicinal chemistry, 2022-02, Vol.229, p.114044-114044, Article 114044 [Periódico revisado por pares]France: Elsevier Masson SASTexto completo disponível |