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PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
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PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma

Duchatel, Ryan J ; Jackson, Evangeline R ; Parackal, Sarah G ; Kiltschewskij, Dylan ; Findlay, Izac J ; Mannan, Abdul ; Staudt, Dilana E ; Thomas, Bryce C ; Germon, Zacary P ; Laternser, Sandra ; Kearney, Padraic S ; Jamaluddin, M Fairuz B ; Douglas, Alicia M ; Beitaki, Tyrone ; McEwen, Holly P ; Persson, Mika L ; Hocke, Emily A ; Jain, Vaibhav ; Aksu, Michael ; Manning, Elizabeth E ; Murray, Heather C ; Verrills, Nicole M ; Sun, Claire Xin ; Daniel, Paul ; Vilain, Ricardo E ; Skerrett-Byrne, David A ; Nixon, Brett ; Hua, Susan ; de Bock, Charles E ; Colino-Sanguino, Yolanda ; Valdes-Mora, Fatima ; Tsoli, Maria ; Ziegler, David S ; Cairns, Murray J ; Raabe, Eric H ; Vitanza, Nicholas A ; Hulleman, Esther ; Phoenix, Timothy N ; Koschmann, Carl ; Alvaro, Frank ; Dayas, Christopher V ; Tinkle, Christopher L ; Wheeler, Helen ; Whittle, James R ; Eisenstat, David D ; Firestein, Ron ; Mueller, Sabine ; Valvi, Santosh ; Hansford, Jordan R ; Ashley, David M ; Gregory, Simon G ; Kilburn, Lindsay B ; Nazarian, Javad ; Cain, Jason E ; Dun, Matthew D

The Journal of clinical investigation, 2024-03, Vol.134 (6), p.1-20 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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2
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG
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Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG

Balakrishnan, Ilango ; Danis, Etienne ; Pierce, Angela ; Madhavan, Krishna ; Wang, Dong ; Dahl, Nathan ; Sanford, Bridget ; Birks, Diane K. ; Davidson, Nate ; Metselaar, Dennis S. ; Meel, Michaël Hananja ; Lemma, Rakeb ; Donson, Andrew ; Vijmasi, Trinka ; Katagi, Hiroaki ; Sola, Ismail ; Fosmire, Susan ; Alimova, Irina ; Steiner, Jenna ; Gilani, Ahmed ; Hulleman, Esther ; Serkova, Natalie J. ; Hashizume, Rintaro ; Hawkins, Cynthia ; Carcaboso, Angel M. ; Gupta, Nalin ; Monje, Michelle ; Jabado, Nada ; Jones, Kenneth ; Foreman, Nicholas ; Green, Adam ; Vibhakar, Rajeev ; Venkataraman, Sujatha

Cell reports (Cambridge), 2020-10, Vol.33 (3), p.108286-108286, Article 108286 [Periódico revisado por pares]

United States: Elsevier Inc

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3
Phase I trial of panobinostat in children with diffuse intrinsic pontine glioma: A report from the Pediatric Brain Tumor Consortium (PBTC-047)
Phase I trial of panobinostat in children with diffuse intrinsic pontine glioma: A report from the Pediatric Brain Tumor Consortium (PBTC-047)
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Phase I trial of panobinostat in children with diffuse intrinsic pontine glioma: A report from the Pediatric Brain Tumor Consortium (PBTC-047)

Monje, Michelle ; Cooney, Tabitha ; Glod, John ; Huang, Jie ; Peer, Cody J ; Faury, Damien ; Baxter, Patricia ; Kramer, Kim ; Lenzen, Alicia ; Robison, Nathan J ; Kilburn, Lindsay ; Vinitsky, Anna ; Figg, William D ; Jabado, Nada ; Fouladi, Maryam ; Fangusaro, Jason ; Onar-Thomas, Arzu ; Dunkel, Ira J ; Warren, Katherine E

Neuro-oncology (Charlottesville, Va.), 2023-12, Vol.25 (12), p.2262-2272 [Periódico revisado por pares]

US: Oxford University Press

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4
Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma
Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma
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Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma

Noll, Alyssa ; Myers, Carrie ; Biery, Matthew C ; Meechan, Michael ; Tahiri, Sophie ; Rajendran, Asmitha ; Berens, Michael E ; Paine, Danyelle ; Byron, Sara ; Zhang, Jiaming ; Winter, Conrad ; Pakiam, Fiona ; Leary, Sarah E S ; Cole, Bonnie L ; Jackson, Evangeline R ; Dun, Matthew D ; Foster, Jessica B ; Evans, Myron K ; Pattwell, Siobhan S ; Olson, James M ; Vitanza, Nicholas A

Neoplasia (New York, N.Y.), 2023-09, Vol.43, p.100921-100921, Article 100921 [Periódico revisado por pares]

United States: Neoplasia Press

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5
Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma
Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma
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Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma

Zhao, Guisheng ; Newbury, Patrick ; Ishi, Yukitomo ; Chekalin, Eugene ; Zeng, Billy ; Glicksberg, Benjamin S ; Wen, Anita ; Paithankar, Shreya ; Sasaki, Takahiro ; Suri, Amreena ; Nazarian, Javad ; Pacold, Michael E ; Brat, Daniel J ; Nicolaides, Theodore ; Chen, Bin ; Hashizume, Rintaro

Acta neuropathologica communications, 2022-10, Vol.10 (1), p.150-15, Article 150 [Periódico revisado por pares]

England: BioMed Central Ltd

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6
Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of sulfasalazine for the treatment of progressing malignant gliomas in adults
Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of sulfasalazine for the treatment of progressing malignant gliomas in adults
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Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of sulfasalazine for the treatment of progressing malignant gliomas in adults

Robe, Pierre A ; Martin, Didier H ; Nguyen-Khac, Minh T ; Artesi, Maria ; Deprez, Manuel ; Albert, Adelin ; Vanbelle, Sophie ; Califice, Stephane ; Bredel, Markus ; Bours, Vincent

BMC cancer, 2009-10, Vol.9 (1), p.372-372, Article 372 [Periódico revisado por pares]

England: BioMed Central Ltd

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7
Valproic acid for the treatment of malignant gliomas: review of the preclinical rationale and published clinical results
Valproic acid for the treatment of malignant gliomas: review of the preclinical rationale and published clinical results
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Valproic acid for the treatment of malignant gliomas: review of the preclinical rationale and published clinical results

Berendsen, Sharon ; Broekman, Marike ; Seute, Tatjana ; Snijders, Tom ; van Es, Corine ; de Vos, Filip ; Regli, Luca ; Robe, Pierre

Expert opinion on investigational drugs, 2012-09, Vol.21 (9), p.1391-1415 [Periódico revisado por pares]

England: Informa UK, Ltd

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8
In Silico prediction of the molecular basis of ClTx and AaCTx interaction with matrix metalloproteinase-2 (MMP-2) to inhibit glioma cell invasion
In Silico prediction of the molecular basis of ClTx and AaCTx interaction with matrix metalloproteinase-2 (MMP-2) to inhibit glioma cell invasion
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In Silico prediction of the molecular basis of ClTx and AaCTx interaction with matrix metalloproteinase-2 (MMP-2) to inhibit glioma cell invasion

Othman, Houcemeddine ; Wieninger, Silke Andrea ; ElAyeb, Mohamed ; Nilges, Michael ; Srairi-Abid, Najet

Journal of biomolecular structure & dynamics, 2017-10, Vol.35 (13), p.2815-2829 [Periódico revisado por pares]

England: Taylor & Francis

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9
Reversing glioma malignancy: a new look at the role of antidepressant drugs as adjuvant therapy for glioblastoma multiforme
Reversing glioma malignancy: a new look at the role of antidepressant drugs as adjuvant therapy for glioblastoma multiforme
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Reversing glioma malignancy: a new look at the role of antidepressant drugs as adjuvant therapy for glioblastoma multiforme

Bielecka-Wajdman, Anna M. ; Lesiak, Marta ; Ludyga, Tomasz ; Sieroń, Aleksander ; Obuchowicz, Ewa

Cancer chemotherapy and pharmacology, 2017-06, Vol.79 (6), p.1249-1256 [Periódico revisado por pares]

Berlin/Heidelberg: Springer Berlin Heidelberg

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10
Improving outcomes for neurofibromatosis 1-associated brain tumors
Improving outcomes for neurofibromatosis 1-associated brain tumors
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Improving outcomes for neurofibromatosis 1-associated brain tumors

Brossier, Nicole M ; Gutmann, David H

Expert review of anticancer therapy, 2015-04, Vol.15 (4), p.415-423 [Periódico revisado por pares]

England: Informa UK, Ltd

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