skip to main content
Idioma:
Primo Advanced Search
Primo Advanced Search Query Term
Primo Advanced Search Query Term
Primo Advanced Search Query Term
Primo Advanced Search prefilters
Busca Simples
Resultados 1 2 3 4 5 next page
Mostrar Somente
Refinado por: Base de dados/Biblioteca: Publisher website remover
Result Number Material Type Add to My Shelf Action Record Details and Options
1
Metabolism, Excretion, and Pharmacokinetics of [14C]INCB018424, a Selective Janus Tyrosine Kinase 1/2 Inhibitor, in Humans
Metabolism, Excretion, and Pharmacokinetics of [14C]INCB018424, a Selective Janus Tyrosine Kinase 1/2 Inhibitor, in Humans
Material Type:
Artigo 		Adicionar ao Meu Espaço

Metabolism, Excretion, and Pharmacokinetics of [14C]INCB018424, a Selective Janus Tyrosine Kinase 1/2 Inhibitor, in Humans

SHILLING, Adam D ; NEDZA, Frank M ; SHEPARD, Stacey ; RODGERS, James ; YUE, Tai-Yuen ; YELESWARAM, Swamy ; EMM, Thomas ; DIAMOND, Sharon ; MCKEEVER, Edward ; PUNWANI, Naresh ; WILLIAMS, William ; ARVANITIS, Argyrios ; GALYA, Laurine G ; MEI LI

Drug metabolism and disposition, 2010-11, Vol.38 (11), p.2023-2031 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

Texto completo disponível

Citações Citado por
2
Efficacy and Safety of Oral Janus Kinase 1 Inhibitor Abrocitinib for Patients With Atopic Dermatitis: A Phase 2 Randomized Clinical Trial
Efficacy and Safety of Oral Janus Kinase 1 Inhibitor Abrocitinib for Patients With Atopic Dermatitis: A Phase 2 Randomized Clinical Trial
Material Type:
Artigo 		Adicionar ao Meu Espaço

Efficacy and Safety of Oral Janus Kinase 1 Inhibitor Abrocitinib for Patients With Atopic Dermatitis: A Phase 2 Randomized Clinical Trial

Gooderham, Melinda J ; Forman, Seth B ; Bissonnette, Robert ; Beebe, Jean S ; Zhang, Weidong ; Banfield, Chris ; Zhu, Linda ; Papacharalambous, Jocelyne ; Vincent, Michael S ; Peeva, Elena

Archives of dermatology (1960), 2019-12, Vol.155 (12), p.1371-1379 [Periódico revisado por pares]

United States: American Medical Association

Texto completo disponível

Citações Citado por
3
Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition
Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition
Material Type:
Artigo 		Adicionar ao Meu Espaço

Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition

Lupardus, Patrick J. ; Ultsch, Mark ; Wallweber, Heidi ; Kohli, Pawan Bir ; Johnson, Adam R. ; Eigenbrot, Charles

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (22), p.8025-8030 [Periódico revisado por pares]

United States: National Academy of Sciences

Texto completo disponível

Citações Citado por
4
Heterodimeric JAK―STAT activation as a mechanism of persistence to JAK2 inhibitor therapy
Heterodimeric JAK―STAT activation as a mechanism of persistence to JAK2 inhibitor therapy
Material Type:
Artigo 		Adicionar ao Meu Espaço

Heterodimeric JAK―STAT activation as a mechanism of persistence to JAK2 inhibitor therapy

KOPPIKAR, Priya ; BHAGWAT, Neha ; LEUNG, Laura ; WEINSTEIN, Abby ; MARUBAYASHI, Sachie ; GOEL, Aviva ; GÖNEN, Mithat ; ESTROV, Zeev ; EBERT, Benjamin L ; CHIOSIS, Gabriela ; NIMER, Stephen D ; BERNSTEIN, Bradley E ; KILPIVAARA, Outi ; VERSTOVSEK, Srdan ; LEVINE, Ross L ; MANSHOURI, Taghi ; ADLI, Mazhar ; HRICIK, Todd ; FAN LIU ; SAUNDERS, Lindsay M ; MULLALLY, Ann ; ABDEL-WAHAB, Omar

Nature (London), 2012-09, Vol.489 (7414), p.155-159 [Periódico revisado por pares]

London: Nature Publishing Group

Texto completo disponível

Citações Citado por
5
Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy
Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy
Material Type:
Artigo 		Adicionar ao Meu Espaço

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

Porpaczy, Edit ; Tripolt, Sabrina ; Hoelbl-Kovacic, Andrea ; Gisslinger, Bettina ; Bago-Horvath, Zsuzsanna ; Casanova-Hevia, Emilio ; Clappier, Emmanuelle ; Decker, Thomas ; Fajmann, Sabine ; Fux, Daniela A. ; Greiner, Georg ; Gueltekin, Sinan ; Heller, Gerwin ; Herkner, Harald ; Hoermann, Gregor ; Kiladjian, Jean-Jacques ; Kolbe, Thomas ; Kornauth, Christoph ; Krauth, Maria-Theresa ; Kralovics, Robert ; Muellauer, Leonhard ; Mueller, Mathias ; Prchal-Murphy, Michaela ; Putz, Eva Maria ; Raffoux, Emmanuel ; Schiefer, Ana-Iris ; Schmetterer, Klaus ; Schneckenleithner, Christine ; Simonitsch-Klupp, Ingrid ; Skrabs, Cathrin ; Sperr, Wolfgang R. ; Staber, Philipp Bernhard ; Strobl, Birgit ; Valent, Peter ; Jaeger, Ulrich ; Gisslinger, Heinz ; Sexl, Veronika

Blood, 2018-08, Vol.132 (7), p.694-706 [Periódico revisado por pares]

United States: Elsevier Inc

Texto completo disponível

Citações Citado por
6
Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling
Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling
Material Type:
Artigo 		Adicionar ao Meu Espaço

Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling

Rutherford, Claire ; Speirs, Claire ; Williams, Jamie J L ; Ewart, Marie-Ann ; Mancini, Sarah J ; Hawley, Simon A ; Delles, Christian ; Viollet, Benoit ; Costa-Pereira, Ana P ; Baillie, George S ; Salt, Ian P ; Palmer, Timothy M

Science signaling, 2016-11, Vol.9 (453), p.ra109-ra109 [Periódico revisado por pares]

United States

Texto completo disponível

Citações Citado por
7
The role of Janus kinase signaling in the pathology of atopic dermatitis
The role of Janus kinase signaling in the pathology of atopic dermatitis
Material Type:
Artigo 		Adicionar ao Meu Espaço

The role of Janus kinase signaling in the pathology of atopic dermatitis

Guttman-Yassky, Emma ; Irvine, Alan D ; Brunner, Patrick M ; Kim, Brian S ; Boguniewicz, Mark ; Parmentier, Julie ; Platt, Andrew M ; Kabashima, Kenji

Journal of allergy and clinical immunology, 2023-12, Vol.152 (6), p.1394-1404 [Periódico revisado por pares]

United States

Texto completo disponível

Citações Citado por
8
Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance
Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance
Material Type:
Artigo 		Adicionar ao Meu Espaço

Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance

QUINTAS-CARDAMA, Alfonso ; VERSTOVSEK, Srdan

Clinical cancer research, 2013-04, Vol.19 (8), p.1933-1940 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

Texto completo disponível

Citações Citado por
9
Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia
Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia
Material Type:
Artigo 		Adicionar ao Meu Espaço

Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia

Maude, Shannon L. ; Tasian, Sarah K. ; Vincent, Tiffaney ; Hall, Junior W. ; Sheen, Cecilia ; Roberts, Kathryn G. ; Seif, Alix E. ; Barrett, David M. ; Chen, I-Ming ; Collins, J. Racquel ; Mullighan, Charles G. ; Hunger, Stephen P. ; Harvey, Richard C. ; Willman, Cheryl L. ; Fridman, Jordan S. ; Loh, Mignon L. ; Grupp, Stephan A. ; Teachey, David T.

Blood, 2012-10, Vol.120 (17), p.3510-3518 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

Texto completo disponível

Citações Citado por
10
JAK mutations in high-risk childhood acute lymphoblastic leukemia
JAK mutations in high-risk childhood acute lymphoblastic leukemia
Material Type:
Artigo 		Adicionar ao Meu Espaço

JAK mutations in high-risk childhood acute lymphoblastic leukemia

Mullighan, Charles G ; Zhang, Jinghui ; Harvey, Richard C ; Collins-Underwood, J. Racquel ; Schulman, Brenda A ; Phillips, Letha A ; Tasian, Sarah K ; Loh, Mignon L ; Su, Xiaoping ; Liu, Wei ; Devidas, Meenakshi ; Atlas, Susan R ; Chen, I. Ming ; Clifford, Robert J ; Gerhard, Daniela S ; Carroll, William L ; Reaman, Gregory H ; Smith, Malcolm ; Downing, James R ; Hunger, Stephen P ; Willman, Cheryl L

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (23), p.9414-9418 [Periódico revisado por pares]

United States: National Academy of Sciences

Texto completo disponível

Citações Citado por
Resultados 1 2 3 4 5 next page

Personalize Seus Resultados

  1. Editar

Refine Search Results

Expandir Meus Resultados

  1.   

Mostrar Somente

  1. Recursos Online (4.618)
  2. Revistas revisadas por pares (4.586)

Refinar Meus Resultados

Tipo de Recurso 

  1. Artigos  (4.670)
  2. Anais de Congresso  (5)
  3. Reports  (3)
  4. Resenhas  (3)
  5. magazinearticle  (3)
  6. Mais opções open sub menu

Data de Publicação 

De até
Refinar
  1. Antes de1995  (41)
  2. 1995Até2001  (687)
  3. 2002Até2008  (1.201)
  4. 2009Até2016  (1.593)
  5. Após 2016  (1.162)
  6. Mais opções open sub menu

Idioma 

  1. Inglês  (4.682)
  2. Japonês  (1.376)
  3. Francês  (3)
  4. Norueguês  (2)
  5. Chinês  (1)
  6. Espanhol  (1)
  7. Mais opções open sub menu

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.