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Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex
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Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex

Fu, Tian-Min ; Li, Yang ; Lu, Alvin ; Li, Zongli ; Vajjhala, Parimala R. ; Cruz, Anthony C. ; Srivastava, Devendra B. ; DiMaio, Frank ; Penczek, Pawel A. ; Siegel, Richard M. ; Stacey, Katryn J. ; Egelman, Edward H. ; Wu, Hao

Molecular cell, 2016-10, Vol.64 (2), p.236-250 [Periódico revisado por pares]

United States: Elsevier Inc

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Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate
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Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

Fox, Joanna L ; Hughes, Michelle A ; Meng, Xin ; Sarnowska, Nikola A ; Powley, Ian R ; Jukes-Jones, Rebekah ; Dinsdale, David ; Ragan, Timothy J ; Fairall, Louise ; Schwabe, John W R ; Morone, Nobuhiro ; Cain, Kelvin ; MacFarlane, Marion

Nature communications, 2021-02, Vol.12 (1), p.819-17, Article 819 [Periódico revisado por pares]

England: Nature Publishing Group

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Cell cycle and apoptosis regulation by NFAT transcription factors: new roles for an old player
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Cell cycle and apoptosis regulation by NFAT transcription factors: new roles for an old player

Mognol, G P ; Carneiro, F R G ; Robbs, B K ; Faget, D V ; Viola, J P B

Cell death & disease, 2016-04, Vol.7 (4), p.e2199-e2199 [Periódico revisado por pares]

England: Springer Nature B.V

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4
Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis
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Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis

Yang, Chao-Yu ; Lien, Chia-I ; Tseng, Yi-Chun ; Tu, Yi-Fan ; Kulczyk, Arkadiusz W ; Lu, Yen-Chen ; Wang, Yin-Ting ; Su, Tsung-Wei ; Hsu, Li-Chung ; Lo, Yu-Chih ; Lin, Su-Chang

Nature communications, 2024-05, Vol.15 (1), p.3791-3791, Article 3791 [Periódico revisado por pares]

England: Nature Publishing Group

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Conserved folding landscape of monomeric initiator caspases
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Conserved folding landscape of monomeric initiator caspases

Nag, Mithun ; Clark, A. Clay

The Journal of biological chemistry, 2023-04, Vol.299 (4), p.103075-103075, Article 103075 [Periódico revisado por pares]

United States: Elsevier Inc

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An engineered construct of cFLIP provides insight into DED1 structure and interactions
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An engineered construct of cFLIP provides insight into DED1 structure and interactions

Panaitiu, Alexandra E. ; Basiashvili, Tamar ; Mierke, Dale F. ; Pellegrini, Maria

Structure (London), 2022-02, Vol.30 (2), p.229-239.e5 [Periódico revisado por pares]

United States: Elsevier Ltd

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7
Long and short isoforms of c-FLIP act as control checkpoints of DED filament assembly
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Long and short isoforms of c-FLIP act as control checkpoints of DED filament assembly

Hillert, Laura K ; Ivanisenko, Nikita V ; Espe, Johannes ; König, Corinna ; Ivanisenko, Vladimir A ; Kähne, Thilo ; Lavrik, Inna N

Oncogene, 2020-02, Vol.39 (8), p.1756-1772 [Periódico revisado por pares]

England: Nature Publishing Group

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Proliferative versus apoptotic functions of caspase-8 Hetero or homo: The caspase-8 dimer controls cell fate
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Proliferative versus apoptotic functions of caspase-8 Hetero or homo: The caspase-8 dimer controls cell fate

van Raam, Bram J ; Salvesen, Guy S

Biochimica et biophysica acta. Proteins and proteomics, 2012-01, Vol.1824 (1), p.113-122 [Periódico revisado por pares]

Elsevier B.V

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Mechanism of procaspase-8 activation by c-FLIPL
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Mechanism of procaspase-8 activation by c-FLIPL

Yu, Jong W ; Jeffrey, Philip D ; Shi, Yigong

Proceedings of the National Academy of Sciences - PNAS, 2009-05, Vol.106 (20), p.8169-8174 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
Reconstruction of the Fas-Based Death-Inducing Signaling Complex (DISC) Using a Protein–Protein Docking Meta-Approach
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Reconstruction of the Fas-Based Death-Inducing Signaling Complex (DISC) Using a Protein–Protein Docking Meta-Approach

Mahdizadeh, Sayyed Jalil ; Thomas, Melissa ; Eriksson, Leif A

Journal of chemical information and modeling, 2021-07, Vol.61 (7), p.3543-3558 [Periódico revisado por pares]

United States: American Chemical Society

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