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1
Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patients
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Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patients

Woolbright, Benjamin L ; McGill, Mitchell R ; Staggs, Vincent S ; Winefield, Robert D ; Gholami, Parviz ; Olyaee, Mojtaba ; Sharpe, Matthew R ; Curry, Steven C ; Lee, William M ; Jaeschke, Hartmut

Toxicological sciences, 2014-12, Vol.142 (2), p.436-444 [Periódico revisado por pares]

United States: Oxford University Press

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2
Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis
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Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis

McGreal, Steven R ; Bhushan, Bharat ; Walesky, Chad ; McGill, Mitchell R ; Lebofsky, Margitta ; Kandel, Sylvie E ; Winefield, Robert D ; Jaeschke, Hartmut ; Zachara, Natasha E ; Zhang, Zhen ; Tan, Ee Phie ; Slawson, Chad ; Apte, Udayan

Toxicological sciences, 2018-04, Vol.162 (2), p.599-610 [Periódico revisado por pares]

United States: Oxford University Press

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3
Possible Role of Extracellular Vesicles in Hepatotoxicity of Acetaminophen
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Possible Role of Extracellular Vesicles in Hepatotoxicity of Acetaminophen

Šrajer Gajdošik, Martina ; Kovač Peić, Anamarija ; Begić, Marija ; Grbčić, Petra ; Brilliant, Kate E ; Hixson, Douglas C ; Josić, Djuro

International journal of molecular sciences, 2022-08, Vol.23 (16), p.8870 [Periódico revisado por pares]

Switzerland: MDPI AG

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4
The acetaminophen metabolite N-acetyl-p-benzoquinone imine (NAPQI) inhibits glutathione synthetase in vitro; a clue to the mechanism of 5-oxoprolinuric acidosis?
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The acetaminophen metabolite N-acetyl-p-benzoquinone imine (NAPQI) inhibits glutathione synthetase in vitro; a clue to the mechanism of 5-oxoprolinuric acidosis?

Walker, Valerie ; Mills, Graham A. ; Anderson, Mary E. ; Ingle, Brandall L. ; Jackson, John M. ; Moss, Charlotte L. ; Sharrod-Cole, Hayley ; Skipp, Paul J.

Xenobiotica, 2017-02, Vol.47 (2), p.164-175 [Periódico revisado por pares]

England: Taylor & Francis

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5
The protective effects of carvacrol and thymol against paracetamol–induced toxicity on human hepatocellular carcinoma cell lines (HepG2)
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The protective effects of carvacrol and thymol against paracetamol–induced toxicity on human hepatocellular carcinoma cell lines (HepG2)

Palabiyik, SS ; Karakus, E ; Halici, Z ; Cadirci, E ; Bayir, Y ; Ayaz, G ; Cinar, I

Human & experimental toxicology, 2016-12, Vol.35 (12), p.1252-1263 [Periódico revisado por pares]

London, England: SAGE Publications

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6
Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity
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Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity

Skoko, John J ; Wakabayashi, Nobunao ; Noda, Kentaro ; Kimura, Shoko ; Tobita, Kimimasa ; Shigemura, Norihisa ; Tsujita, Tadayuki ; Yamamoto, Masayuki ; Kensler, Thomas W

Toxicological sciences, 2014-09, Vol.141 (1), p.112-119 [Periódico revisado por pares]

United States: Oxford University Press

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7
Glutathione metabolism modeling: A mechanism for liver drug-robustness and a new biomarker strategy
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Glutathione metabolism modeling: A mechanism for liver drug-robustness and a new biomarker strategy

Geenen, Suzanne ; du Preez, Franco B. ; Snoep, Jacky L. ; Foster, Alison J. ; Sarda, Sunil ; Kenna, J. Gerry ; Wilson, Ian D. ; Westerhoff, Hans V.

Biochimica et biophysica acta. General subjects, 2013-10, Vol.1830 (10), p.4943-4959 [Periódico revisado por pares]

Elsevier B.V

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8
Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription
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Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription

PARK, WOO-JAE ; KIM, SO-YEON ; KIM, YE-RYUNG ; PARK, JOO-WON

International journal of molecular medicine, 2016-03, Vol.37 (3), p.613-622 [Periódico revisado por pares]

Athens: D.A. Spandidos

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9
PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury
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PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury

North, Trista E. ; Babu, I. Ramesh ; Vedder, Lea M. ; Lord, Allegra M. ; Wishnok, John S. ; Tannenbaum, Steven R. ; Zon, Leonard I. ; Goessling, Wolfram

Proceedings of the National Academy of Sciences - PNAS, 2010-10, Vol.107 (40), p.17315-17320 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice
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Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice

Bhushan, Bharat ; Chavan, Hemantkumar ; Borude, Prachi ; Xie, Yuchao ; Du, Kuo ; McGill, Mitchell R ; Lebofsky, Margitta ; Jaeschke, Hartmut ; Krishnamurthy, Partha ; Apte, Udayan

Toxicological sciences, 2017-02, Vol.155 (2), p.363-378 [Periódico revisado por pares]

United States: Oxford University Press

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