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FDA Approval Summary: Selumetinib for Plexiform Neurofibroma
FDA Approval Summary: Selumetinib for Plexiform Neurofibroma
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FDA Approval Summary: Selumetinib for Plexiform Neurofibroma

Casey, Denise ; Demko, Suzanne ; Sinha, Arup ; Mishra-Kalyani, Pallavi S ; Shen, Yuan-Li ; Khasar, Sachia ; Goheer, M Anwar ; Helms, Whitney S ; Pan, Lili ; Xu, Yuan ; Fan, Jianghong ; Leong, Ruby ; Liu, Jiang ; Yang, Yuching ; Windsor, Katherine ; Ou, Mei ; Stephens, Olen ; Oh, Byeongtaek ; Reaman, Gregory H ; Nair, Abhilasha ; Shord, Stacy S ; Bhatnagar, Vishal ; Daniels, Selena R ; Sickafuse, Sharon ; Goldberg, Kirsten B ; Theoret, Marc R ; Pazdur, Richard ; Singh, Harpreet

Clinical cancer research, 2021-08, Vol.27 (15), p.4142-4146 [Periódico revisado por pares]

United States

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2
Design of amidobenzimidazole STING receptor agonists with systemic activity
Design of amidobenzimidazole STING receptor agonists with systemic activity
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Design of amidobenzimidazole STING receptor agonists with systemic activity

Ramanjulu, Joshi M ; Pesiridis, G Scott ; Yang, Jingsong ; Concha, Nestor ; Singhaus, Robert ; Zhang, Shu-Yun ; Tran, Jean-Luc ; Moore, Patrick ; Lehmann, Stephanie ; Eberl, H Christian ; Muelbaier, Marcel ; Schneck, Jessica L ; Clemens, Jim ; Adam, Michael ; Mehlmann, John ; Romano, Joseph ; Morales, Angel ; Kang, James ; Leister, Lara ; Graybill, Todd L ; Charnley, Adam K ; Ye, Guosen ; Nevins, Neysa ; Behnia, Kamelia ; Wolf, Amaya I ; Kasparcova, Viera ; Nurse, Kelvin ; Wang, Liping ; Puhl, Ana C ; Li, Yue ; Klein, Michael ; Hopson, Christopher B ; Guss, Jeffrey ; Bantscheff, Marcus ; Bergamini, Giovanna ; Reilly, Michael A ; Lian, Yiqian ; Duffy, Kevin J ; Adams, Jerry ; Foley, Kevin P ; Gough, Peter J ; Marquis, Robert W ; Smothers, James ; Hoos, Axel ; Bertin, John

Nature (London), 2018-12, Vol.564 (7736), p.439-443 [Periódico revisado por pares]

England: Nature Publishing Group

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3
Veliparib with First-Line Chemotherapy and as Maintenance Therapy in Ovarian Cancer
Veliparib with First-Line Chemotherapy and as Maintenance Therapy in Ovarian Cancer
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Veliparib with First-Line Chemotherapy and as Maintenance Therapy in Ovarian Cancer

Coleman, Robert L ; Fleming, Gini F ; Brady, Mark F ; Swisher, Elizabeth M ; Steffensen, Karina D ; Friedlander, Michael ; Okamoto, Aikou ; Moore, Kathleen N ; Efrat Ben-Baruch, Noa ; Werner, Theresa L ; Cloven, Noelle G ; Oaknin, Ana ; DiSilvestro, Paul A ; Morgan, Mark A ; Nam, Joo-Hyun ; Leath, Charles A ; Nicum, Shibani ; Hagemann, Andrea R ; Littell, Ramey D ; Cella, David ; Baron-Hay, Sally ; Garcia-Donas, Jesus ; Mizuno, Mika ; Bell-McGuinn, Katherine ; Sullivan, Danielle M ; Bach, Bruce A ; Bhattacharya, Sudipta ; Ratajczak, Christine K ; Ansell, Peter J ; Dinh, Minh H ; Aghajanian, Carol ; Bookman, Michael A

The New England journal of medicine, 2019-12, Vol.381 (25), p.2403-2415 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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4
The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia
The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia
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The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia

Stein, Eytan M. ; Garcia-Manero, Guillermo ; Rizzieri, David A. ; Tibes, Raoul ; Berdeja, Jesus G. ; Savona, Michael R. ; Jongen-Lavrenic, Mojca ; Altman, Jessica K. ; Thomson, Blythe ; Blakemore, Stephen J. ; Daigle, Scott R. ; Waters, Nigel J. ; Suttle, A. Benjamin ; Clawson, Alicia ; Pollock, Roy ; Krivtsov, Andrei ; Armstrong, Scott A. ; DiMartino, Jorge ; Hedrick, Eric ; Löwenberg, Bob ; Tallman, Martin S.

Blood, 2018-06, Vol.131 (24), p.2661-2669 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Treating cancer with selective CDK4/6 inhibitors
Treating cancer with selective CDK4/6 inhibitors
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Treating cancer with selective CDK4/6 inhibitors

O'Leary, Ben ; Finn, Richard S ; Turner, Nicholas C

Nature reviews. Clinical oncology, 2016-07, Vol.13 (7), p.417-430 [Periódico revisado por pares]

England: Nature Publishing Group

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6
Red cell distribution width as a novel prognostic marker in heart failure : Data from the CHARM program and the duke databank
Red cell distribution width as a novel prognostic marker in heart failure : Data from the CHARM program and the duke databank
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Red cell distribution width as a novel prognostic marker in heart failure : Data from the CHARM program and the duke databank

FELKER, G. Michael ; ALLEN, Larry A ; GRANGER, Christopher B ; POCOCK, Stuart J ; SHAW, Linda K ; MCMURRAY, John J. V ; PFEFFER, Marc A ; SWEDBERG, Karl ; DUOLAO WANG ; YUSUF, Salim ; MICHELSON, Eric L

Journal of the American College of Cardiology, 2007-07, Vol.50 (1), p.40-47 [Periódico revisado por pares]

New York, NY: Elsevier Science

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7
The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade
The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade
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The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade

Schaer, David A. ; Beckmann, Richard P. ; Dempsey, Jack A. ; Huber, Lysiane ; Forest, Amelie ; Amaladas, Nelusha ; Li, Yanxia ; Wang, Ying Cindy ; Rasmussen, Erik R. ; Chin, Darin ; Capen, Andrew ; Carpenito, Carmine ; Staschke, Kirk A. ; Chung, Linda A. ; Litchfield, Lacey M. ; Merzoug, Farhana F. ; Gong, Xueqian ; Iversen, Philip W. ; Buchanan, Sean ; de Dios, Alfonso ; Novosiadly, Ruslan D. ; Kalos, Michael

Cell reports (Cambridge), 2018-03, Vol.22 (11), p.2978-2994 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Therapeutic evolution of benzimidazole derivatives in the last quinquennial period
Therapeutic evolution of benzimidazole derivatives in the last quinquennial period
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Therapeutic evolution of benzimidazole derivatives in the last quinquennial period

Akhtar, Wasim ; Khan, Mohemmed Faraz ; Verma, Garima ; Shaquiquzzaman, M. ; Rizvi, M.A. ; Mehdi, Syed Hassan ; Akhter, Mymoona ; Alam, M. Mumtaz

European journal of medicinal chemistry, 2017-01, Vol.126, p.705-753 [Periódico revisado por pares]

France: Elsevier Masson SAS

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9
Aspirin and Extended-Release Dipyridamole versus Clopidogrel for Recurrent Stroke
Aspirin and Extended-Release Dipyridamole versus Clopidogrel for Recurrent Stroke
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Aspirin and Extended-Release Dipyridamole versus Clopidogrel for Recurrent Stroke

Sacco, Ralph L ; Diener, Hans-Christoph ; Yusuf, Salim ; Cotton, Daniel ; Ôunpuu, Stephanie ; Lawton, William A ; Palesch, Yuko ; Martin, Reneé H ; Albers, Gregory W ; Bath, Philip ; Bornstein, Natan ; Chan, Bernard P.L ; Chen, Sien-Tsong ; Cunha, Luis ; Dahlöf, Björn ; De Keyser, Jacques ; Donnan, Geoffrey A ; Estol, Conrado ; Gorelick, Philip ; Gu, Vivian ; Hermansson, Karin ; Hilbrich, Lutz ; Kaste, Markku ; Lu, Chuanzhen ; Machnig, Thomas ; Pais, Prem ; Roberts, Robin ; Skvortsova, Veronika ; Teal, Philip ; Toni, Danilo ; VanderMaelen, Cam ; Voigt, Thor ; Weber, Michael ; Yoon, Byung-Woo

The New England journal of medicine, 2008-09, Vol.359 (12), p.1238-1251 [Periódico revisado por pares]

Boston, MA: Massachusetts Medical Society

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10
Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2 × 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol
Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2 × 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol
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Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2 × 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol

Gulati, Geeta ; Heck, Siri Lagethon ; Ree, Anne Hansen ; Hoffmann, Pavel ; Schulz-Menger, Jeanette ; Fagerland, Morten W ; Gravdehaug, Berit ; von Knobelsdorff-Brenkenhoff, Florian ; Bratland, Åse ; Storås, Tryggve H ; Hagve, Tor-Arne ; Røsjø, Helge ; Steine, Kjetil ; Geisler, Jürgen ; Omland, Torbjørn

European heart journal, 2016-06, Vol.37 (21), p.1671-1680 [Periódico revisado por pares]

England: Oxford University Press

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