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| Result Number | Material Type | Add to My Shelf Action | Record Details and Options |
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| 1 |
Material Type: Artigo
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Ado-trastuzumab Emtansine (T-DM1): An Antibody–Drug Conjugate (ADC) for HER2-Positive Breast CancerLambert, John M ; Chari, Ravi V. JJournal of medicinal chemistry, 2014-08, Vol.57 (16), p.6949-6964 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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The concordance between nonclinical and phase I clinical cardiovascular assessment from a cross-company data sharing initiativeEwart, Lorna ; Aylott, Mike ; Deurinck, Mark ; Engwall, Mike ; Gallacher, David J ; Geys, Helena ; Jarvis, Philip ; Ju, Haisong ; Leishman, Derek ; Leong, Louise ; McMahon, Nick ; Mead, Andy ; Milliken, Phil ; Suter, Willi ; Teisman, Ard ; Van Ammel, Karel ; Vargas, Hugo M ; Wallis, Rob ; Valentin, Jean-PierreToxicological sciences, 2014-12, Vol.142 (2), p.427-435 [Periódico revisado por pares]United StatesTexto completo disponível |
| 3 |
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A product of independent beta probabilities dose escalation design for dual-agent phase I trialsMander, Adrian P. ; Sweeting, Michael J.Statistics in medicine, 2015-04, Vol.34 (8), p.1261-1276 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
| 4 |
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Approaches using molecular imaging technology — use of PET in clinical microdose studiesWagner, Claudia C. ; Langer, OliverAdvanced drug delivery reviews, 2011-06, Vol.63 (7), p.539-546 [Periódico revisado por pares]Netherlands: Elsevier B.VTexto completo disponível |
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Safety Profile of Nivolumab Monotherapy: A Pooled Analysis of Patients With Advanced MelanomaWeber, Jeffrey S ; Hodi, F Stephen ; Wolchok, Jedd D ; Topalian, Suzanne L ; Schadendorf, Dirk ; Larkin, James ; Sznol, Mario ; Long, Georgina V ; Li, Hewei ; Waxman, Ian M ; Jiang, Joel ; Robert, CarolineJournal of clinical oncology, 2017-03, Vol.35 (7), p.785-792 [Periódico revisado por pares]United StatesTexto completo disponível |
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American Society of Clinical Oncology policy statement update: the critical role of phase I trials in cancer research and treatmentWeber, Jeffrey S ; Levit, Laura A ; Adamson, Peter C ; Bruinooge, Suanna ; Burris, 4th, Howard A ; Carducci, Michael A ; Dicker, Adam P ; Gönen, Mithat ; Keefe, Stephen M ; Postow, Michael A ; Thompson, Michael A ; Waterhouse, David M ; Weiner, Susan L ; Schuchter, Lynn MJournal of clinical oncology, 2015-01, Vol.33 (3), p.278-284 [Periódico revisado por pares]United States: American Society of Clinical OncologyTexto completo disponível |
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Material Type: Artigo
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The COVID-19 vaccine development landscapeThanh Le, Tung ; Andreadakis, Zacharias ; Kumar, Arun ; Gómez Román, Raúl ; Tollefsen, Stig ; Saville, Melanie ; Mayhew, StephenNature reviews. Drug discovery, 2020-05, Vol.19 (5), p.305-306 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
| 8 |
Material Type: Artigo
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Pre-clinical animal models are poor predictors of human toxicities in phase 1 oncology clinical trialsAtkins, Johnique T ; George, Goldy C ; Hess, Kenneth ; Marcelo-Lewis, Kathrina L ; Yuan, Ying ; Borthakur, Gautam ; Khozin, Sean ; LoRusso, Patricia ; Hong, David SBritish journal of cancer, 2020-11, Vol.123 (10), p.1496-1501 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
| 9 |
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Embracing model-based designs for dose-finding trialsLove, Sharon B ; Brown, Sarah ; Weir, Christopher J ; Harbron, Chris ; Yap, Christina ; Gaschler-Markefski, Birgit ; Matcham, James ; Caffrey, Louise ; McKevitt, Christopher ; Clive, Sally ; Craddock, Charlie ; Spicer, James ; Cornelius, VictoriaBritish journal of cancer, 2017-07, Vol.117 (3), p.332-339 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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An oral SARS-CoV-2 M pro inhibitor clinical candidate for the treatment of COVID-19Owen, Dafydd R ; Allerton, Charlotte M N ; Anderson, Annaliesa S ; Aschenbrenner, Lisa ; Avery, Melissa ; Berritt, Simon ; Boras, Britton ; Cardin, Rhonda D ; Carlo, Anthony ; Coffman, Karen J ; Dantonio, Alyssa ; Di, Li ; Eng, Heather ; Ferre, RoseAnn ; Gajiwala, Ketan S ; Gibson, Scott A ; Greasley, Samantha E ; Hurst, Brett L ; Kadar, Eugene P ; Kalgutkar, Amit S ; Lee, Jack C ; Lee, Jisun ; Liu, Wei ; Mason, Stephen W ; Noell, Stephen ; Novak, Jonathan J ; Obach, R Scott ; Ogilvie, Kevin ; Patel, Nandini C ; Pettersson, Martin ; Rai, Devendra K ; Reese, Matthew R ; Sammons, Matthew F ; Sathish, Jean G ; Singh, Ravi Shankar P ; Steppan, Claire M ; Stewart, Al E ; Tuttle, Jamison B ; Updyke, Lawrence ; Verhoest, Patrick R ; Wei, Liuqing ; Yang, Qingyi ; Zhu, YuaoScience (American Association for the Advancement of Science), 2021-12, Vol.374 (6575), p.1586-1593 [Periódico revisado por pares]United StatesTexto completo disponível |
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