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Material Type: Artigo
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Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 responsePark, Donglim Esther ; Cheng, Jingwei ; Berrios, Christian ; Montero, Joan ; Cortés-Cros, Marta ; Ferretti, Stéphane ; Arora, Reety ; Tillgren, Michelle L. ; Gokhale, Prafulla C. ; DeCaprio, James A.Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (3), p.1027-1032 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growthCortés-Cros, Marta ; Hemmerlin, Christelle ; Ferretti, Stephane ; Zhang, Juan ; Gounarides, John S. ; Yin, Hong ; Muller, Alban ; Haberkorn, Anne ; Chene, Patrick ; Sellers, William R. ; Hofmann, FrancescoProceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (2), p.489-494 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Challenges for the Discovery of Non‐Covalent WRN Helicase InhibitorsHeuser, Alisa ; Abdul Rahman, Wassim ; Bechter, Elisabeth ; Blank, Jutta ; Buhr, Sylvia ; Erdmann, Dirk ; Fontana, Patrizia ; Mermet‐Meillon, Fanny ; Meyerhofer, Marco ; Strang, Ross ; Schrapp, Maxime ; Zimmermann, Catherine ; Cortes‐Cros, Marta ; Möbitz, Henrik ; Hamon, JacquesChemMedChem, 2024-04, Vol.19 (8), p.e202300613-n/a [Periódico revisado por pares]Germany: Wiley Subscription Services, IncTexto completo disponível |
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Material Type: Artigo
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Phosphorylated FTY720 promotes astrocyte migration through sphingosine‐1‐phosphate receptorsMullershausen, Florian ; Craveiro, Luis M. ; Shin, Youngah ; Cortes‐Cros, Marta ; Bassilana, Frederic ; Osinde, Maribel ; Wishart, William L. ; Guerini, Danilo ; Thallmair, Michaela ; Schwab, Martin E. ; Sivasankaran, Rajeev ; Seuwen, Klaus ; Dev, Kumlesh K.Journal of neurochemistry, 2007-08, Vol.102 (4), p.1151-1161 [Periódico revisado por pares]Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Dose and Schedule Determine Distinct Molecular Mechanisms Underlying the Efficacy of the p53-MDM2 Inhibitor HDM201Jeay, Sébastien ; Ferretti, Stéphane ; Holzer, Philipp ; Fuchs, Jeanette ; Chapeau, Emilie A ; Wartmann, Markus ; Sterker, Dario ; Romanet, Vincent ; Murakami, Masato ; Kerr, Grainne ; Durand, Eric Y ; Gaulis, Swann ; Cortes-Cros, Marta ; Ruetz, Stephan ; Stachyra, Therese-Marie ; Kallen, Joerg ; Furet, Pascal ; Würthner, Jens ; Guerreiro, Nelson ; Halilovic, Ensar ; Jullion, Astrid ; Kauffmann, Audrey ; Kuriakose, Emil ; Wiesmann, Marion ; Jensen, Michael R ; Hofmann, Francesco ; Sellers, William RCancer research (Chicago, Ill.), 2018-11, Vol.78 (21), p.6257-6267 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Front Cover: Challenges for the Discovery of Non‐Covalent WRN Helicase Inhibitors (ChemMedChem 8/2024)Heuser, Alisa ; Abdul Rahman, Wassim ; Bechter, Elisabeth ; Blank, Jutta ; Buhr, Sylvia ; Erdmann, Dirk ; Fontana, Patrizia ; Mermet‐Meillon, Fanny ; Meyerhofer, Marco ; Strang, Ross ; Schrapp, Maxime ; Zimmermann, Catherine ; Cortes‐Cros, Marta ; Möbitz, Henrik ; Hamon, JacquesChemMedChem, 2024-04, Vol.19 (8), p.n/a [Periódico revisado por pares]Weinheim: Wiley Subscription Services, IncTexto completo disponível |
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Material Type: Artigo
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Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancersFerretti, Stephane ; Hamon, Jacques ; de Kanter, Ruben ; Scheufler, Clemens ; Andraos-Rey, Rita ; Barbe, Stephanie ; Bechter, Elisabeth ; Blank, Jutta ; Bordas, Vincent ; Dammassa, Ernesta ; Decker, Andrea ; Di Nanni, Noemi ; Dourdoigne, Marion ; Gavioli, Elena ; Hattenberger, Marc ; Heuser, Alisa ; Hemmerlin, Christelle ; Hinrichs, Jürgen ; Kerr, Grainne ; Laborde, Laurent ; Jaco, Isabel ; Núñez, Eloísa Jiménez ; Martus, Hans-Joerg ; Quadt, Cornelia ; Reschke, Markus ; Romanet, Vincent ; Schaeffer, Fanny ; Schoepfer, Joseph ; Schrapp, Maxime ; Strang, Ross ; Voshol, Hans ; Wartmann, Markus ; Welly, Sarah ; Zécri, Frédéric ; Hofmann, Francesco ; Möbitz, Henrik ; Cortés-Cros, MartaNature (London), 2024-05, Vol.629 (8011), p.443-449 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi ScreeningMcDonald, E. Robert ; de Weck, Antoine ; Schlabach, Michael R. ; Billy, Eric ; Mavrakis, Konstantinos J. ; Hoffman, Gregory R. ; Belur, Dhiren ; Castelletti, Deborah ; Frias, Elizabeth ; Gampa, Kalyani ; Golji, Javad ; Kao, Iris ; Li, Li ; Megel, Philippe ; Perkins, Thomas A. ; Ramadan, Nadire ; Ruddy, David A. ; Silver, Serena J. ; Sovath, Sosathya ; Stump, Mark ; Weber, Odile ; Widmer, Roland ; Yu, Jianjun ; Yu, Kristine ; Yue, Yingzi ; Abramowski, Dorothee ; Ackley, Elizabeth ; Barrett, Rosemary ; Berger, Joel ; Bernard, Julie L. ; Billig, Rebecca ; Brachmann, Saskia M. ; Buxton, Frank ; Caothien, Roger ; Caushi, Justina X. ; Chung, Franklin S. ; Cortés-Cros, Marta ; deBeaumont, Rosalie S. ; Delaunay, Clara ; Desplat, Aurore ; Duong, William ; Dwoske, Donald A. ; Eldridge, Richard S. ; Farsidjani, Ali ; Feng, Fei ; Feng, JiaJia ; Flemming, Daisy ; Forrester, William ; Galli, Giorgio G. ; Gao, Zhenhai ; Gauter, François ; Gibaja, Veronica ; Haas, Kristy ; Hattenberger, Marc ; Hood, Tami ; Hurov, Kristen E. ; Jagani, Zainab ; Jenal, Mathias ; Johnson, Jennifer A. ; Jones, Michael D. ; Kapoor, Avnish ; Korn, Joshua ; Liu, Jilin ; Liu, Qiumei ; Liu, Shumei ; Liu, Yue ; Loo, Alice T. ; Macchi, Kaitlin J. ; Martin, Typhaine ; McAllister, Gregory ; Meyer, Amandine ; Mollé, Sandra ; Pagliarini, Raymond A. ; Phadke, Tanushree ; Repko, Brian ; Schouwey, Tanja ; Shanahan, Frances ; Shen, Qiong ; Stamm, Christelle ; Stephan, Christine ; Stucke, Volker M. ; Tiedt, Ralph ; Varadarajan, Malini ; Venkatesan, Kavitha ; Vitari, Alberto C. ; Wallroth, Marco ; Weiler, Jan ; Zhang, Jing ; Mickanin, Craig ; Myer, Vic E. ; Porter, Jeffery A. ; Lai, Albert ; Bitter, Hans ; Lees, Emma ; Keen, Nicholas ; Kauffmann, Audrey ; Stegmeier, Frank ; Hofmann, Francesco ; Schmelzle, Tobias ; Sellers, William R.Cell, 2017-07, Vol.170 (3), p.577-592.e10 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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EXTH-95. UNCOVERING THERAPEUTIC VULNERABILITIES IN MISMATCH REPAIR-DEFICIENT GLIOMASPal, Sangita ; Boynton, Adam ; Johnston, Ryan ; Currimjee, Naomi ; Qian, Kenin ; Touat, Mehdi ; Bellamy, Charlotte ; Ho, Patricia ; Root, David ; Persky, Nicole ; Goodale, Amy ; Berstler, Jim ; Miller, Lisa ; Guletsky, Alex ; Cortes-Cros, Marta ; Ligon, Keith ; Beroukhim, Rameen ; Bandopadhayay, PratitiNeuro-oncology (Charlottesville, Va.), 2022-11, Vol.24 (Supplement_7), p.vii231-vii232 [Periódico revisado por pares]US: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Abstract LB222: Elucidating the cellular responses and mechanism of action of 177Lu-based radioligand therapyRanzani, Marco ; Hindupur, Sravanth ; Cicconi, Alessandro ; Sastre-Moreno, Guillermo ; Kristian, Alexander ; Engstler, Barbara Schacher ; Pinch, Benika ; Hartnagel, Charlene ; Gorses, Delphine ; Simon, Elise ; Mandon, Emeline ; Schramm, Emilien ; Schaeffer, Fanny ; Reber, Josefine ; Barys, Louise ; Deberle, Luisa ; Walter, Milene ; Bessey, Ralph ; Destefani, Riccardo ; Miot, Xavier ; Elinati, Elias ; Shao, Nan ; Boursier, Marie ; Barlow, Joseph ; Thapa, Asmita ; Galbiati, Alessandro ; Grande, Diego ; Rajendra, Eeson ; Martin, Niall ; Smith, Graeme ; Schmelzle, Tobias ; Reschke, Markus ; Robinson, Helen ; Cortes-Cros, MartaCancer research (Chicago, Ill.), 2024-04, Vol.84 (7_Supplement), p.LB222-LB222 [Periódico revisado por pares]Texto completo disponível |