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Cell cycle proteins as promising targets in cancer therapy
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Cell cycle proteins as promising targets in cancer therapy

Otto, Tobias ; Sicinski, Piotr

Nature reviews. Cancer, 2017-02, Vol.17 (2), p.93-115 [Peer Reviewed Journal]

England: Nature Publishing Group

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2
Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors
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Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors

Romero, F. Anthony ; Taylor, Alexander M ; Crawford, Terry D ; Tsui, Vickie ; Côté, Alexandre ; Magnuson, Steven

Journal of medicinal chemistry, 2016-02, Vol.59 (4), p.1271-1298 [Peer Reviewed Journal]

United States: American Chemical Society

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3
6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities
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Article
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6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities

Amiable, Claire ; Paoletti, Julie ; Haouz, Ahmed ; Padilla, André ; Labesse, Gilles ; Kaminski, Pierre-Alexandre ; Pochet, Sylvie

European journal of medicinal chemistry, 2014-10, Vol.85, p.418-437 [Peer Reviewed Journal]

France: Elsevier Masson SAS

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4
The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches
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The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches

Joerger, Andreas C ; Fersht, Alan R

Annual review of biochemistry, 2016-06, Vol.85 (1), p.375-404 [Peer Reviewed Journal]

United States: Annual Reviews

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5
Getting up to speed with transcription elongation by RNA polymerase II
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Getting up to speed with transcription elongation by RNA polymerase II

Jonkers, Iris ; Lis, John T

Nature reviews. Molecular cell biology, 2015-03, Vol.16 (3), p.167-177 [Peer Reviewed Journal]

England: Nature Publishing Group

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6
Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation
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Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation

Zhang, Pingzhao ; Wang, Dejie ; Zhao, Yu ; Ren, Shancheng ; Gao, Kun ; Ye, Zhenqing ; Wang, Shangqian ; Pan, Chun-Wu ; Zhu, Yasheng ; Yan, Yuqian ; Yang, Yinhui ; Wu, Di ; He, Yundong ; Zhang, Jun ; Lu, Daru ; Liu, Xiuping ; Yu, Long ; Zhao, Shimin ; Li, Yao ; Lin, Dong ; Wang, Yuzhuo ; Wang, Liguo ; Chen, Yu ; Sun, Yinghao ; Wang, Chenji ; Huang, Haojie

Nature medicine, 2017-09, Vol.23 (9), p.1055-1062 [Peer Reviewed Journal]

United States: Nature Publishing Group

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7
The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ
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The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ

Chang, Lei ; Azzolin, Luca ; Di Biagio, Daniele ; Zanconato, Francesca ; Battilana, Giusy ; Lucon Xiccato, Romy ; Aragona, Mariaceleste ; Giulitti, Stefano ; Panciera, Tito ; Gandin, Alessandro ; Sigismondo, Gianluca ; Krijgsveld, Jeroen ; Fassan, Matteo ; Brusatin, Giovanna ; Cordenonsi, Michelangelo ; Piccolo, Stefano

Nature (London), 2018-11, Vol.563 (7730), p.265-269 [Peer Reviewed Journal]

England: Nature Publishing Group

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8
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration
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Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration

Mohamed, Tamer M.A. ; Ang, Yen-Sin ; Radzinsky, Ethan ; Zhou, Ping ; Huang, Yu ; Elfenbein, Arye ; Foley, Amy ; Magnitsky, Sergey ; Srivastava, Deepak

Cell, 2018-03, Vol.173 (1), p.104-116.e12 [Peer Reviewed Journal]

United States: Elsevier Inc

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9
Transcription Elongation Can Affect Genome 3D Structure
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Transcription Elongation Can Affect Genome 3D Structure

Heinz, Sven ; Texari, Lorane ; Hayes, Michael G.B. ; Urbanowski, Matthew ; Chang, Max W. ; Givarkes, Ninvita ; Rialdi, Alexander ; White, Kris M. ; Albrecht, Randy A. ; Pache, Lars ; Marazzi, Ivan ; García-Sastre, Adolfo ; Shaw, Megan L. ; Benner, Christopher

Cell, 2018-09, Vol.174 (6), p.1522-1536.e22 [Peer Reviewed Journal]

United States: Elsevier Inc

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10
XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer
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XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer

Kim, Jimi ; McMillan, Elizabeth ; Kim, Hyun Seok ; Venkateswaran, Niranjan ; Makkar, Gurbani ; Rodriguez-Canales, Jaime ; Villalobos, Pamela ; Neggers, Jasper Edgar ; Mendiratta, Saurabh ; Wei, Shuguang ; Landesman, Yosef ; Senapedis, William ; Baloglu, Erkan ; Chow, Chi-Wan B ; Frink, Robin E ; Gao, Boning ; Roth, Michael ; Minna, John D ; Daelemans, Dirk ; Wistuba, Ignacio I ; Posner, Bruce A ; Scaglioni, Pier Paolo ; White, Michael A

Nature (London), 2016-10, Vol.538 (7623), p.114-117 [Peer Reviewed Journal]

England: Nature Publishing Group

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