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1 |
Material Type: Dissertação de Mestrado
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Efeito do inibidor de proteinase de origem vegetal EcTI, sobre a lesão pulmonar induzida pela elastase em camundongos C57BI6Theodoro Junior, Osmar AparecidoBiblioteca Digital de Teses e Dissertações da USP; Universidade de São Paulo; Faculdade de Medicina 2014-06-02Acesso online. A biblioteca também possui exemplares impressos. |
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Material Type: Artigo
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Modelling ligand selectivity of serine proteases using integrative proteochemometric approaches improves model performance and allows the multi-target dependent interpretation of featuresAin, Qurrat U ; Méndez-Lucio, Oscar ; Ciriano, Isidro Cortés ; Malliavin, Thérèse ; van Westen, Gerard J P ; Bender, AndreasIntegrative biology (Cambridge), 2014-11, Vol.6 (11), p.1023-1033 [Periódico revisado por pares]England: Royal Society of ChemistryTexto completo disponível |
3 |
Material Type: Artigo
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hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6Egelrud, T. ; Brattsand, M. ; Kreutzmann, P. ; Walden, M. ; Vitzithum, K. ; Marx, U.C. ; Forssmann, W.G. ; Mägert, H.J.British journal of dermatology (1951), 2005-12, Vol.153 (6), p.1200-1203 [Periódico revisado por pares]Oxford, UK: Blackwell Science LtdTexto completo disponível |
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Material Type: Artigo
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Organic Carbamates in Drug Design and Medicinal ChemistryGhosh, Arun K ; Brindisi, MargheritaJournal of medicinal chemistry, 2015-04, Vol.58 (7), p.2895-2940 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastaseZheng, Qinheng ; Woehl, Jordan L. ; Kitamura, Seiya ; Santos-Martins, Diogo ; Smedley, Christopher J. ; Li, Gencheng ; Forli, Stefano ; Moses, John E. ; Wolan, Dennis W. ; Sharpless, K. BarryProceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (38), p.18808-18814 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Virtual Screening of Natural Products against Type II Transmembrane Serine Protease (TMPRSS2), the Priming Agent of Coronavirus 2 (SARS-CoV-2)Rahman, Noor ; Basharat, Zarrin ; Yousuf, Muhammad ; Castaldo, Giuseppe ; Rastrelli, Luca ; Khan, HaroonMolecules (Basel, Switzerland), 2020-05, Vol.25 (10), p.2271 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
7 |
Material Type: Artigo
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Candidate drugs against SARS-CoV-2 and COVID-19McKee, Dwight L. ; Sternberg, Ariane ; Stange, Ulrike ; Laufer, Stefan ; Naujokat, CordPharmacological research, 2020-07, Vol.157, p.104859-104859, Article 104859 [Periódico revisado por pares]Netherlands: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeuticShapira, Tirosh ; Monreal, I Abrrey ; Dion, Sébastien P ; Buchholz, David W ; Imbiakha, Brian ; Olmstead, Andrea D ; Jager, Mason ; Désilets, Antoine ; Gao, Guang ; Martins, Mathias ; Vandal, Thierry ; Thompson, Connor A H ; Chin, Aaleigha ; Rees, William D ; Steiner, Theodore ; Nabi, Ivan Robert ; Marsault, Eric ; Sahler, Julie ; Diel, Diego G ; Van de Walle, Gerlinde R ; August, Avery ; Whittaker, Gary R ; Boudreault, Pierre-Luc ; Leduc, Richard ; Aguilar, Hector C ; Jean, FrançoisNature (London), 2022-05, Vol.605 (7909), p.340-348 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
9 |
Material Type: Artigo
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Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infectionWettstein, Lukas ; Weil, Tatjana ; Conzelmann, Carina ; Müller, Janis A ; Groß, Rüdiger ; Hirschenberger, Maximilian ; Seidel, Alina ; Klute, Susanne ; Zech, Fabian ; Prelli Bozzo, Caterina ; Preising, Nico ; Fois, Giorgio ; Lochbaum, Robin ; Knaff, Philip Maximilian ; Mailänder, Volker ; Ständker, Ludger ; Thal, Dietmar Rudolf ; Schumann, Christian ; Stenger, Steffen ; Kleger, Alexander ; Lochnit, Günter ; Mayer, Benjamin ; Ruiz-Blanco, Yasser B ; Hoffmann, Markus ; Sparrer, Konstantin M J ; Pöhlmann, Stefan ; Sanchez-Garcia, Elsa ; Kirchhoff, Frank ; Frick, Manfred ; Münch, JanNature communications, 2021-03, Vol.12 (1), p.1726-1726, Article 1726 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Is Multitask Deep Learning Practical for Pharma?Ramsundar, Bharath ; Liu, Bowen ; Wu, Zhenqin ; Verras, Andreas ; Tudor, Matthew ; Sheridan, Robert P ; Pande, VijayJournal of chemical information and modeling, 2017-08, Vol.57 (8), p.2068-2076 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |