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1 |
Material Type: Artigo
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Regio-Selective Chemical-Enzymatic Synthesis of Pyrimidine Nucleotides Facilitates RNA Structure and Dynamics StudiesAlvarado, Luigi J. ; LeBlanc, Regan M. ; Longhini, Andrew P. ; Keane, Sarah C. ; Jain, Niyati ; Yildiz, Zehra F. ; Tolbert, Blanton S. ; D'Souza, Victoria M. ; Summers, Michael F. ; Kreutz, Christoph ; Dayie, T. KwakuChembiochem : a European journal of chemical biology, 2014-07, Vol.15 (11), p.1573-1577 [Periódico revisado por pares]Weinheim: WILEY-VCH VerlagTexto completo disponível |
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Material Type: Artigo
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Functional Pyrazolo[1,5- a ]pyrimidines: Current Approaches in Synthetic Transformations and Uses As an Antitumor ScaffoldArias-Gómez, Andres ; Godoy, Andrés ; Portilla, JaimeMolecules (Basel, Switzerland), 2021-05, Vol.26 (9), p.2708 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Material Type: Artigo
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Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advancesAli, Eslam M.H. ; Abdel-Maksoud, Mohammed S. ; Oh, Chang-HyunBioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1159-1194 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Design and Synthesis of New Thiophene/Thieno[2,3- d ]pyrimidines along with Their Cytotoxic Biological Evaluation as Tyrosine Kinase Inhibitors in Addition to Their Apoptotic and Autophagic InductionElmongy, Elshaymaa I ; Attallah, Nashwah G M ; Altwaijry, Najla ; AlKahtani, Manal Mubarak ; Henidi, Hanan AliMolecules (Basel, Switzerland), 2021-12, Vol.27 (1), p.123 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Material Type: Artigo
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In silico design of novel probes for the atypical opioid receptor MRGPRX2Lansu, Katherine ; Karpiak, Joel ; Liu, Jing ; Huang, Xi-Ping ; McCorvy, John D ; Kroeze, Wesley K ; Che, Tao ; Nagase, Hiroshi ; Carroll, Frank I ; Jin, Jian ; Shoichet, Brian K ; Roth, Bryan LNature chemical biology, 2017-05, Vol.13 (5), p.529-536 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Heterocyclic steroids: Efficient routes for annulation of pentacyclic steroidal pyrimidinesMonier, M. ; El-Mekabaty, Ahmed ; Abdel-Latif, Doaa ; Doğru Mert, Başak ; Elattar, Khaled M.Steroids, 2020-02, Vol.154, p.108548-108548, Article 108548 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Synthesis and Antiviral Screening of Some Thieno[2,3-d]Pyrimidine NucleosidesRashad, A. E. ; Ali, M. A.Nucleosides, nucleotides & nucleic acids, 2006-01, Vol.25 (1), p.17-28 [Periódico revisado por pares]United States: Taylor & Francis GroupTexto completo disponível |
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Material Type: Artigo
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Synthesis of a new series of pyrazolo[1,5-a]pyrimidines as CDK2 inhibitors and anti-leukemiaAlmehmadi, Samar J. ; Alsaedi, Amani M.R. ; Harras, Marwa F. ; Farghaly, Thoraya A.Bioorganic chemistry, 2021-12, Vol.117, p.105431-105431, Article 105431 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
9 |
Material Type: Artigo
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Novel pyrazolo[3,4-d]pyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile and caspase-3-mediated apoptosisMaher, Mai ; Kassab, Asmaa E. ; Zaher, Ashraf F. ; Mahmoud, ZeinabJournal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.532-546 [Periódico revisado por pares]England: Taylor & FrancisTexto completo disponível |
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Material Type: Artigo
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Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitorsZhang, Tinghu ; Kwiatkowski, Nicholas ; Olson, Calla M ; Dixon-Clarke, Sarah E ; Abraham, Brian J ; Greifenberg, Ann K ; Ficarro, Scott B ; Elkins, Jonathan M ; Liang, Yanke ; Hannett, Nancy M ; Manz, Theresa ; Hao, Mingfeng ; Bartkowiak, Bartlomiej ; Greenleaf, Arno L ; Marto, Jarrod A ; Geyer, Matthias ; Bullock, Alex N ; Young, Richard A ; Gray, Nathanael SNature chemical biology, 2016-10, Vol.12 (10), p.876-884 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |