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Functional Pyrazolo[1,5- a ]pyrimidines: Current Approaches in Synthetic Transformations and Uses As an Antitumor Scaffold
Functional Pyrazolo[1,5- a ]pyrimidines: Current Approaches in Synthetic Transformations and Uses As an Antitumor Scaffold
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Functional Pyrazolo[1,5- a ]pyrimidines: Current Approaches in Synthetic Transformations and Uses As an Antitumor Scaffold

Arias-Gómez, Andres ; Godoy, Andrés ; Portilla, Jaime

Molecules (Basel, Switzerland), 2021-05, Vol.26 (9), p.2708 [Periódico revisado por pares]

Switzerland: MDPI AG

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2
New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies
New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies
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New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies

Othman, Ismail M.M. ; Alamshany, Zahra M. ; Tashkandi, Nada Y. ; Gad-Elkareem, Mohamed A.M. ; Anwar, Manal M. ; Nossier, Eman S.

Bioorganic chemistry, 2021-09, Vol.114, p.105078, Article 105078 [Periódico revisado por pares]

United States: Elsevier Inc

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3
Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances
Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances
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Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances

Ali, Eslam M.H. ; Abdel-Maksoud, Mohammed S. ; Oh, Chang-Hyun

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1159-1194 [Periódico revisado por pares]

England: Elsevier Ltd

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4
Triazolopyrimidine Derivatives: An Updated Review on Recent Advances in Synthesis, Biological Activities and Drug Delivery Aspects
Triazolopyrimidine Derivatives: An Updated Review on Recent Advances in Synthesis, Biological Activities and Drug Delivery Aspects
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Triazolopyrimidine Derivatives: An Updated Review on Recent Advances in Synthesis, Biological Activities and Drug Delivery Aspects

Abdelkhalek, Ahmed S ; Attia, Mohamed S ; Kamal, Mohammad A

Current medicinal chemistry, 2024-01, Vol.31 (14), p.1896-1919 [Periódico revisado por pares]

United Arab Emirates: Bentham Science Publishers

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5
Heterocyclic steroids: Efficient routes for annulation of pentacyclic steroidal pyrimidines
Heterocyclic steroids: Efficient routes for annulation of pentacyclic steroidal pyrimidines
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Heterocyclic steroids: Efficient routes for annulation of pentacyclic steroidal pyrimidines

Monier, M. ; El-Mekabaty, Ahmed ; Abdel-Latif, Doaa ; Doğru Mert, Başak ; Elattar, Khaled M.

Steroids, 2020-02, Vol.154, p.108548-108548, Article 108548 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Design, Synthesis and Anticancer Activity of New Polycyclic: Imidazole, Thiazine, Oxathiine, Pyrrolo-Quinoxaline and Thienotriazolopyrimidine Derivatives
Design, Synthesis and Anticancer Activity of New Polycyclic: Imidazole, Thiazine, Oxathiine, Pyrrolo-Quinoxaline and Thienotriazolopyrimidine Derivatives
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Design, Synthesis and Anticancer Activity of New Polycyclic: Imidazole, Thiazine, Oxathiine, Pyrrolo-Quinoxaline and Thienotriazolopyrimidine Derivatives

Abu-Hashem, Ameen Ali ; Al-Hussain, Sami A ; Zaki, Magdi E A

Molecules (Basel, Switzerland), 2021-04, Vol.26 (7), p.2031 [Periódico revisado por pares]

Switzerland: MDPI AG

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7
Novel pyrazolo[3,4-d]pyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile and caspase-3-mediated apoptosis
Novel pyrazolo[3,4-d]pyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile and caspase-3-mediated apoptosis
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Novel pyrazolo[3,4-d]pyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile and caspase-3-mediated apoptosis

Maher, Mai ; Kassab, Asmaa E. ; Zaher, Ashraf F. ; Mahmoud, Zeinab

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.532-546 [Periódico revisado por pares]

England: Taylor & Francis

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8
Synthesis and in vitro antitumor evaluation of some new thiophenes and thieno[2,3-d]pyrimidine derivatives
Synthesis and in vitro antitumor evaluation of some new thiophenes and thieno[2,3-d]pyrimidine derivatives
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Synthesis and in vitro antitumor evaluation of some new thiophenes and thieno[2,3-d]pyrimidine derivatives

Fouad, Mahasen M. ; El-Bendary, Eman R. ; suddek, Ghada M. ; Shehata, Ihsan A. ; El-Kerdawy, Mohamed M.

Bioorganic chemistry, 2018-12, Vol.81, p.587-598 [Periódico revisado por pares]

United States: Elsevier Inc

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9
Design, Synthesis of New 1,2,4-Triazole/1,3,4-Thiadiazole with Spiroindoline, Imidazo[4,5-b]quinoxaline and Thieno[2,3-d]pyrimidine from Isatin Derivatives as Anticancer Agents
Design, Synthesis of New 1,2,4-Triazole/1,3,4-Thiadiazole with Spiroindoline, Imidazo[4,5-b]quinoxaline and Thieno[2,3-d]pyrimidine from Isatin Derivatives as Anticancer Agents
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Design, Synthesis of New 1,2,4-Triazole/1,3,4-Thiadiazole with Spiroindoline, Imidazo[4,5-b]quinoxaline and Thieno[2,3-d]pyrimidine from Isatin Derivatives as Anticancer Agents

Abu-Hashem, Ameen Ali ; Al-Hussain, Sami A

Molecules (Basel, Switzerland), 2022-01, Vol.27 (3), p.835 [Periódico revisado por pares]

Switzerland: MDPI AG

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10
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines as CDK2 inhibitors and anti-leukemia
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines as CDK2 inhibitors and anti-leukemia
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Synthesis of a new series of pyrazolo[1,5-a]pyrimidines as CDK2 inhibitors and anti-leukemia

Almehmadi, Samar J. ; Alsaedi, Amani M.R. ; Harras, Marwa F. ; Farghaly, Thoraya A.

Bioorganic chemistry, 2021-12, Vol.117, p.105431-105431, Article 105431 [Periódico revisado por pares]

United States: Elsevier Inc

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