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Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesiaDavis, John B ; Gray, Julie ; Gunthorpe, Martin J ; Hatcher, Jonathan P ; Davey, Phil T ; Overend, Philip ; Harries, Mark H ; Latcham, Judi ; Clapham, Colin ; Atkinson, Kirsty ; Hughes, Stephen A ; Rance, Kim ; Grau, Evelyn ; Harper, Alex J ; Pugh, Perdita L ; Rogers, Derek C ; Bingham, Sharon ; Randall, Andrew ; Sheardown, Steven ANature (London), 2000-05, Vol.405 (6783), p.183-187 [Periódico revisado por pares]London: Nature PublishingTexto completo disponível |
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Material Type: Artigo
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Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse modelCatchpole, Ian ; Germaschewski, Volker ; Hoh Kam, Jaimie ; Lundh von Leithner, Peter ; Ford, Susannah ; Gough, Gerald ; Adamson, Peter ; Overend, Philip ; Hilpert, Jan ; López, Francisco J ; Ng, Yin Shan Eric ; Coffey, Pete ; Jeffery, Glen Langmann, ThomasPloS one, 2013-06, Vol.8 (6), p.e65518-e65518 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Longitudinal Circulating Tumor DNA Modeling to Predict Disease Progression in First‐Line Mutant Epidermal Growth Factor Receptor Non‐Small Cell Lung CancerJohnson, Martin ; Serra Traynor, Carlos ; Vishwanathan, Karthick ; Overend, Philip ; Hartmaier, Ryan ; Markovets, Aleksandra ; Chmielecki, Juliann ; Mugundu, Ganesh M. ; Barrett, J. Carl ; Tomkinson, Helen ; Ramalingam, Suresh S.Clinical pharmacology and therapeutics, 2024-02, Vol.115 (2), p.349-360 [Periódico revisado por pares]United StatesTexto completo disponível |
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Abstract CT024: Utility of longitudinal circulating tumor DNA (ctDNA) modeling to predict RECIST-defined progression in first-line patients with epidermal growth factor receptor mutation-positive (EGFRm) advanced non-small cell lung cancer (NSCLC)Vishwanathan, Karthick ; Dunyak, James ; Overend, Philip ; Hartmaier, Ryan ; Markovets, Aleksandra ; Chmielecki, Juliann ; Mugundu, Ganesh ; Barrett, Carl ; Tomkinson, Helen ; Johnson, MartinCancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.CT024-CT024 [Periódico revisado por pares]Texto completo disponível |
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Activity and safety of AZD3759 in EGFR-mutant non-small-cell lung cancer with CNS metastases (BLOOM): a phase 1, open-label, dose-escalation and dose-expansion studyAhn, Myung-Ju ; Kim, Dong-Wan ; Cho, Byoung Chul ; Kim, Sang-We ; Lee, Jong Seok ; Ahn, Jin-Seok ; Kim, Tae Min ; Lin, Chia-Chi ; Kim, Hye Ryun ; John, Thomas ; Kao, Steven ; Goldman, Jonathan W ; Su, Wu-Chou ; Natale, Ronald ; Rabbie, Sarit ; Harrop, Bryony ; Overend, Philip ; Yang, Zhenfan ; Yang, James Chih-HsinThe lancet respiratory medicine, 2017-11, Vol.5 (11), p.891-902 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Evaluation of the spontaneously hypertensive rat as a model of attention deficit hyperactivity disorder: acquisition and performance of the DRL-60s testBull, Eleanor ; Reavill, Charlie ; Hagan, Jim J ; Overend, Philip ; Jones, Declan N.CBehavioural brain research, 2000-04, Vol.109 (1), p.27-35 [Periódico revisado por pares]Shannon: Elsevier B.VTexto completo disponível |
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Subcutaneously Administered Ofatumumab in Rheumatoid Arthritis: A Phase I/II Study of Safety, Tolerability, Pharmacokinetics, and PharmacodynamicsKURRASCH, Regina ; BROWN, Judith C ; CHU, Myron ; CRAIGEN, Jenny ; OVEREND, Philip ; PATEL, Bela ; WOLFE, Steven ; CHANG, David JJournal of rheumatology, 2013-07, Vol.40 (7), p.1089-1096 [Periódico revisado por pares]Toronto, ON: Journal of Rheumatology PublishingTexto completo disponível |
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Material Type: Artigo
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A phase I, open label, multicenter dose escalation study of AZD2811 nanoparticle in patients with advanced solid tumorsJohnson, Melissa Lynne ; Cosaert, Jan G. C. E. ; Falchook, Gerald Steven ; Jones, Suzanne Fields ; Strickland, Donald ; Greenlees, Carol ; Charlton, Julie ; MacDonald, Alexander ; Overend, Philip ; Adelman, Carrie ; Burris, Howard A. ; Pease, Elizabeth J. ; Patel, Gargi Surendra ; Wang, Judy Sing-ZanJournal of clinical oncology, 2019-05, Vol.37 (15_suppl), p.3098-3098 [Periódico revisado por pares]Texto completo disponível |
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Material Type: Artigo
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A Phase I/II, Open-Label, Multicentre 2-Part Study to Assess the Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD2811 Nanoparticle As Monotherapy or in Combination in Treatment-Naïve or Relapsed/Refractory Acute Myeloid Leukaemia/Myelodysplastic Syndrome Patients Not Eligible for Intensive Induction TherapyDonnellan, William B. ; Atallah, Ehab L. ; Asch, Adam S. ; Patel, Manish R ; Charlton, Julie ; MacDonald, Alexander ; Young, Elena ; Sainsbury, Elizabeth ; Strickland, Donald ; Jones, Suzanne ; Overend, Philip ; Adelman, Carrie A. ; Travers, Jon ; Smith, Simon ; Pease, J. Elizabeth ; Brugger, WolframBlood, 2018-11, Vol.132 (Supplement 1), p.4064-4064 [Periódico revisado por pares]Elsevier IncTexto completo disponível |
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Material Type: Artigo
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A Phase I/II Study of AZD2811 Nanoparticles (NP) As Monotherapy or in Combination in Treatment-Naïve or Relapsed/Refractory AML/MDS Patients Not Eligible for Intensive Induction TherapyDonnellan, William B. ; Atallah, Ehab L. ; Asch, Adam S. ; Patel, Manish R. ; Yang, Jay ; Eghtedar, Alireza ; Borthakur, Gautam M. ; Charlton, Julie ; MacDonald, Alexander ; Korzeniowska, Anna ; Sainsbury, Elizabeth ; Strickland, Donald K. ; Jones, Suzanne ; Overend, Philip ; Adelman, Carrie A. ; Fabbri, Giulia ; Travers, Jon ; Smith, Simon ; Pease, J. Elizabeth ; Cosaert, JanBlood, 2019-11, Vol.134 (Supplement_1), p.3919-3919 [Periódico revisado por pares]Elsevier IncTexto completo disponível |