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Material Type: Artigo
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Picking the point of inhibition: a comparative review of PI3K/AKT/mTOR pathway inhibitorsDienstmann, Rodrigo ; Rodon, Jordi ; Serra, Violeta ; Tabernero, JosepMolecular cancer therapeutics, 2014-05, Vol.13 (5), p.1021-1031 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancerGlaviano, Antonino ; Foo, Aaron S. C ; Lam, Hiu Y ; Yap, Kenneth C. H ; Jacot, William ; Jones, Robert H ; Eng, Huiyan ; Nair, Madhumathy G ; Makvandi, Pooyan ; Geoerger, Birgit ; Kulke, Matthew H ; Baird, Richard D ; Prabhu, Jyothi S ; Carbone, Daniela ; Pecoraro, Camilla ; Teh, Daniel B. L ; Sethi, Gautam ; Cavalieri, Vincenzo ; Lin, Kevin H ; Javidi-Sharifi, Nathalie R ; Toska, Eneda ; Davids, Matthew S ; Brown, Jennifer R ; Diana, Patrizia ; Stebbing, Justin ; Fruman, David A ; Kumar, Alan PMolecular cancer, 2023-08, Vol.22 (1), p.1-138, Article 138 [Periódico revisado por pares]London: BioMed Central LtdTexto completo disponível |
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3 |
Material Type: Artigo
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Synthesis of Novel 2,9-Disubstituted-6-morpholino Purine Derivatives Assisted by Virtual Screening and Modelling of Class I PI3K IsoformsLobo, Vítor ; Rocha, Ashly ; Castro, Tarsila G ; Carvalho, Maria AlicePolymers, 2023-03, Vol.15 (7), p.1703 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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4 |
Material Type: Artigo
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Growth and Viability of Cutaneous Squamous Cell Carcinoma Cell Lines Display Different Sensitivities to Isoform-Specific Phosphoinositide 3-Kinase InhibitorsMannella, Viviana ; Boehm, Kira ; Celik, Suheyla ; Ali, Tasnim ; Mirza, Amnah N ; El Hasnaouy, Mariam ; Kaffa, Andreas ; Lyu, Yanshuang ; Kafaei Golahmadi, Donya ; Leigh, Irene M ; Bergamaschi, Daniele ; Harwood, Catherine A ; Maffucci, TaniaInternational journal of molecular sciences, 2021-03, Vol.22 (7), p.3567 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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5 |
Material Type: Artigo
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Investigating the role of class-IA PI 3-kinase isoforms in adipocyte differentiationKim, Ji Eun ; Shepherd, Peter R. ; Chaussade, ClaireBiochemical and biophysical research communications, 2009-02, Vol.379 (4), p.830-834 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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6 |
Material Type: Artigo
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PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancerGlaviano, Antonino ; Foo, Aaron SC ; Lam, Hiu Y ; Yap, Kenneth CH ; Jacot, William ; Jones, Robert H ; Eng, Huiyan ; Nair, Madhumathy G ; Makvandi, Pooyan ; Geoerger, Birgit ; Kulke, Matthew H ; Baird, Richard D ; Prabhu, Jyothi S ; Carbone, Daniela ; Pecoraro, Camilla ; Teh, Daniel BL ; Sethi, Gautam ; Cavalieri, Vincenzo ; Lin, Kevin H ; Javidi-Sharifi, Nathalie R ; Toska, Eneda ; Davids, Matthew S ; Brown, Jennifer R ; Diana, Patrizia ; Stebbing, Justin ; Fruman, David A ; Kumar, Alan Phttp://dx.doi.org/10.1186/s12943-023-01827-6 2023-08Texto completo disponível |
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Material Type: Artigo
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The Upshot of PI3K Inhibitors as Anticancer Arsenal: A Short ReviewShamsi, Farheen ; Rizvi, Mohammad M.A. ; Abid, MohammadCurrent bioactive compounds, 2018, Vol.14 (4), p.331-346 [Periódico revisado por pares]Sharjah: Bentham Science Publishers LtdTexto completo disponível |
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8 |
Material Type: Artigo
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Class-IA Phosphoinositide 3-Kinase p110β Triggers GPCR-Induced Superoxide Production in p110γ-Deficient Murine NeutrophilsKiyomi Nigorikawa ; Kaoru Hazeki ; Takashi Kumazawa ; Yuhta Itoh ; Megumi Hoshi ; Osamu HazekiJournal of Pharmacological Sciences, 2012-12, Vol.120 (4), p.270-279 [Periódico revisado por pares]The Japanese Pharmacological SocietyTexto completo disponível |
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9 |
Material Type: Artigo
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Class-IA Phosphoinositide 3-Kinase p110β Triggers GPCR-Induced Superoxide Production in p110γ-Deficient Murine NeutrophilsNigorikawa, Kiyomi ; Hazeki, Kaoru ; Kumazawa, Takashi ; Itoh, Yuhta ; Hoshi, Megumi ; Hazeki, OsamuJournal of Pharmacological Sciences, 2012, Vol.120(4), pp.270-279 [Periódico revisado por pares]Japan: Elsevier B.VTexto completo disponível |