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Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis
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Artigo
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Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis

Méchin, Marie-Claire ; Cau, Laura ; Galliano, Marie-Florence ; Daunes-Marion, Sylvie ; Poigny, Stéphane ; Vidaluc, Jean-Louis ; Bessou-Touya, Sandrine ; Takahara, Hidenari ; Serre, Guy ; Duplan, Hélène ; Simon, Michel

Journal of dermatological science, 2016-02, Vol.81 (2), p.101-106 [Periódico revisado por pares]

Netherlands: Elsevier Ireland Ltd

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2
Residues Determining the Binding Specificity of Uncompetitive Inhibitors to Tissue‐Nonspecific Alkaline Phosphatase
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Artigo
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Residues Determining the Binding Specificity of Uncompetitive Inhibitors to Tissue‐Nonspecific Alkaline Phosphatase

Kozlenkov, Alexey ; Le Du, Marie Helene ; Cuniasse, Philippe ; Ny, Tor ; Hoylaerts, Marc F ; Millán, José Luis

Journal of bone and mineral research, 2004-11, Vol.19 (11), p.1862-1872 [Periódico revisado por pares]

Washington, DC: John Wiley and Sons and The American Society for Bone and Mineral Research (ASBMR)

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3
Theophylline
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Artigo
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Theophylline

BARNES, Peter J

American journal of respiratory and critical care medicine, 2013-10, Vol.188 (8), p.901-906 [Periódico revisado por pares]

New York, NY: American Thoracic Society

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4
Structure-Bioactivity Relationships of Methylxanthines: Trying to Make Sense of All the Promises and the Drawbacks
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Artigo
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Structure-Bioactivity Relationships of Methylxanthines: Trying to Make Sense of All the Promises and the Drawbacks

Monteiro, João P ; Alves, Marco G ; Oliveira, Pedro F ; Silva, Branca M

Molecules, 2016-07, Vol.21 (8), p.974 [Periódico revisado por pares]

Switzerland: MDPI AG

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5
Synthesis of coumarin-theophylline hybrids as a new class of anti-tubercular and anti-microbial agents
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Artigo
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Synthesis of coumarin-theophylline hybrids as a new class of anti-tubercular and anti-microbial agents

Mangasuli, Sumitra N. ; Hosamani, Kallappa M. ; Devarajegowda, Hirihalli C. ; Kurjogi, Mahantesh M. ; Joshi, Shrinivas D.

European journal of medicinal chemistry, 2018-02, Vol.146, p.747-756 [Periódico revisado por pares]

France: Elsevier Masson SAS

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6
Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite
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Artigo
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Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite

KAZUI, Miho ; NISHIYA, Yumi ; ISHIZUKA, Tomoko ; HAGIHARA, Katsunobu ; FARID, Nagy A ; OKAZAKI, Osamu ; IKEDA, Toshihiko ; KURIHARA, Atsushi

Drug metabolism and disposition, 2010-01, Vol.38 (1), p.92-99 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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7
Mannose-anchored N,N,N-trimethyl chitosan nanoparticles for pulmonary administration of etofylline
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Artigo
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Mannose-anchored N,N,N-trimethyl chitosan nanoparticles for pulmonary administration of etofylline

Pardeshi, Chandrakantsing V. ; Agnihotri, Vinit V. ; Patil, Kusumakar Y. ; Pardeshi, Sagar R. ; Surana, Sanjay J.

International journal of biological macromolecules, 2020-12, Vol.165 (Pt A), p.445-459 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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8
Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1)
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Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1)

Yang, Shyh-Ming ; Yasgar, Adam ; Miller, Bettina ; Lal-Nag, Madhu ; Brimacombe, Kyle ; Hu, Xin ; Sun, Hongmao ; Wang, Amy ; Xu, Xin ; Nguyen, Kimloan ; Oppermann, Udo ; Ferrer, Marc ; Vasiliou, Vasilis ; Simeonov, Anton ; Jadhav, Ajit ; Maloney, David J

Journal of medicinal chemistry, 2015-08, Vol.58 (15), p.5967-5978 [Periódico revisado por pares]

United States: American Chemical Society

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9
Vaccine-driven pharmacodynamic dissection and mitigation of fenethylline psychoactivity
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Artigo
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Vaccine-driven pharmacodynamic dissection and mitigation of fenethylline psychoactivity

Wenthur, Cody J ; Zhou, Bin ; Janda, Kim D

Nature (London), 2017-08, Vol.548 (7668), p.476-479 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Targeting Phosphoinositide-3-Kinase-δ with Theophylline Reverses Corticosteroid Insensitivity in Chronic Obstructive Pulmonary Disease
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Targeting Phosphoinositide-3-Kinase-δ with Theophylline Reverses Corticosteroid Insensitivity in Chronic Obstructive Pulmonary Disease

TO, Yasuo ; ITO, Kazuhiro ; KIZAWA, Yasuo ; FAILLA, Marco ; ITO, Misako ; KUSAMA, Tadashi ; ELLIOTT, W. Mark ; HOGG, James C ; ADCOCK, Ian M ; BARNES, Peter J

American journal of respiratory and critical care medicine, 2010-10, Vol.182 (7), p.897-904 [Periódico revisado por pares]

New York, NY: American Thoracic Society

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