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Bottom-up de novo design of functional proteins with complex structural features
Bottom-up de novo design of functional proteins with complex structural features
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Bottom-up de novo design of functional proteins with complex structural features

Yang, Che ; Sesterhenn, Fabian ; Bonet, Jaume ; van Aalen, Eva A ; Scheller, Leo ; Abriata, Luciano A ; Cramer, Johannes T ; Wen, Xiaolin ; Rosset, Stéphane ; Georgeon, Sandrine ; Jardetzky, Theodore ; Krey, Thomas ; Fussenegger, Martin ; Merkx, Maarten ; Correia, Bruno E

Nature chemical biology, 2021-04, Vol.17 (4), p.492-500 [Periódico revisado por pares]

United States: Nature Publishing Group

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2
De novo protein design enables the precise induction of RSV-neutralizing antibodies
De novo protein design enables the precise induction of RSV-neutralizing antibodies
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De novo protein design enables the precise induction of RSV-neutralizing antibodies

Sesterhenn, Fabian ; Yang, Che ; Bonet, Jaume ; Cramer, Johannes T ; Wen, Xiaolin ; Wang, Yimeng ; Chiang, Chi-I ; Abriata, Luciano A ; Kucharska, Iga ; Castoro, Giacomo ; Vollers, Sabrina S ; Galloux, Marie ; Dheilly, Elie ; Rosset, Stéphane ; Corthésy, Patricia ; Georgeon, Sandrine ; Villard, Mélanie ; Richard, Charles-Adrien ; Descamps, Delphyne ; Delgado, Teresa ; Oricchio, Elisa ; Rameix-Welti, Marie-Anne ; Más, Vicente ; Ervin, Sean ; Eléouët, Jean-François ; Riffault, Sabine ; Bates, John T ; Julien, Jean-Philippe ; Li, Yuxing ; Jardetzky, Theodore ; Krey, Thomas ; Correia, Bruno E

Science (American Association for the Advancement of Science), 2020-05, Vol.368 (6492) [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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3
A rational blueprint for the design of chemically-controlled protein switches
A rational blueprint for the design of chemically-controlled protein switches
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A rational blueprint for the design of chemically-controlled protein switches

Shui, Sailan ; Gainza, Pablo ; Scheller, Leo ; Yang, Che ; Kurumida, Yoichi ; Rosset, Stéphane ; Georgeon, Sandrine ; Di Roberto, Raphaël B. ; Castellanos-Rueda, Rocío ; Reddy, Sai T. ; Correia, Bruno E.

Nature communications, 2021-10, Vol.12 (1), p.1-12, Article 5754 [Periódico revisado por pares]

London: Nature Publishing Group

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4
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms
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Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms

Duarte, Daniel P ; Lamontanara, Allan J ; La Sala, Giuseppina ; Jeong, Sukyo ; Sohn, Yoo-Kyoung ; Panjkovich, Alejandro ; Georgeon, Sandrine ; Kükenshöner, Tim ; Marcaida, Maria J ; Pojer, Florence ; De Vivo, Marco ; Svergun, Dmitri ; Kim, Hak-Sung ; Dal Peraro, Matteo ; Hantschel, Oliver

Nature communications, 2020-05, Vol.11 (1), p.2319-15, Article 2319 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains
Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains
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Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains

Sha, Fern ; Gencer, Emel Basak ; Georgeon, Sandrine ; Koide, Akiko ; Yasui, Norihisa ; Koide, Shohei ; Hantschel, Oliver

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (37), p.14924-14929 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
Single-molecule kinetic analysis of HP1-chromatin binding reveals a dynamic network of histone modification and DNA interactions
Single-molecule kinetic analysis of HP1-chromatin binding reveals a dynamic network of histone modification and DNA interactions
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Single-molecule kinetic analysis of HP1-chromatin binding reveals a dynamic network of histone modification and DNA interactions

Bryan, Louise C ; Weilandt, Daniel R ; Bachmann, Andreas L ; Kilic, Sinan ; Lechner, Carolin C ; Odermatt, Pascal D ; Fantner, Georg E ; Georgeon, Sandrine ; Hantschel, Oliver ; Hatzimanikatis, Vassily ; Fierz, Beat

Nucleic acids research, 2017-10, Vol.45 (18), p.10504-10517 [Periódico revisado por pares]

England: Oxford University Press

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7
The SH2 domain of Abl kinases regulates kinase autophosphorylation by controlling activation loop accessibility
The SH2 domain of Abl kinases regulates kinase autophosphorylation by controlling activation loop accessibility
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The SH2 domain of Abl kinases regulates kinase autophosphorylation by controlling activation loop accessibility

Lamontanara, Allan Joaquim ; Georgeon, Sandrine ; Tria, Giancarlo ; Svergun, Dmitri I ; Hantschel, Oliver

Nature communications, 2014-11, Vol.5 (1), p.5470-5470, Article 5470 [Periódico revisado por pares]

England: Nature Publishing Group

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8
Computational design of anti-CRISPR proteins with improved inhibition potency
Computational design of anti-CRISPR proteins with improved inhibition potency
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Computational design of anti-CRISPR proteins with improved inhibition potency

Mathony, Jan ; Harteveld, Zander ; Schmelas, Carolin ; Upmeier Zu Belzen, Julius ; Aschenbrenner, Sabine ; Sun, Wei ; Hoffmann, Mareike D ; Stengl, Christina ; Scheck, Andreas ; Georgeon, Sandrine ; Rosset, Stéphane ; Wang, Yanli ; Grimm, Dirk ; Eils, Roland ; Correia, Bruno E ; Niopek, Dominik

Nature chemical biology, 2020-07, Vol.16 (7), p.725-730 [Periódico revisado por pares]

United States: Nature Publishing Group

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9
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase
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Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase

Reckel, Sina ; Gehin, Charlotte ; Tardivon, Delphine ; Georgeon, Sandrine ; Kükenshöner, Tim ; Löhr, Frank ; Koide, Akiko ; Buchner, Lena ; Panjkovich, Alejandro ; Reynaud, Aline ; Pinho, Sara ; Gerig, Barbara ; Svergun, Dmitri ; Pojer, Florence ; Güntert, Peter ; Dötsch, Volker ; Koide, Shohei ; Gavin, Anne-Claude ; Hantschel, Oliver

Nature communications, 2017-12, Vol.8 (1), p.2101-14, Article 2101 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Enantioselective Enzymatic Reactions in Miniemulsions as Efficient "Nanoreactors"
Enantioselective Enzymatic Reactions in Miniemulsions as Efficient "Nanoreactors"
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Enantioselective Enzymatic Reactions in Miniemulsions as Efficient "Nanoreactors"

Gröger, Harald ; May, Oliver ; Hüsken, Hendrik ; Georgeon, Sandrine ; Drauz, Karlheinz ; Landfester, Katharina

Angewandte Chemie (International ed.), 2006-02, Vol.45 (10), p.1645-1648 [Periódico revisado por pares]

Weinheim: WILEY-VCH Verlag

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