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1 |
Material Type: Artigo
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Vulnerabilities in coronavirus glycan shields despite extensive glycosylationWatanabe, Yasunori ; Berndsen, Zachary T ; Raghwani, Jayna ; Seabright, Gemma E ; Allen, Joel D ; Pybus, Oliver G ; McLellan, Jason S ; Wilson, Ian A ; Bowden, Thomas A ; Ward, Andrew B ; Crispin, MaxNature communications, 2020-05, Vol.11 (1), p.2688-2688, Article 2688 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus InfectionDetalle, Laurent ; Stohr, Thomas ; Palomo, Concepción ; Piedra, Pedro A ; Gilbert, Brian E ; Mas, Vicente ; Millar, Andrena ; Power, Ultan F ; Stortelers, Catelijne ; Allosery, Koen ; Melero, José A ; Depla, ErikAntimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.6-13 [Periódico revisado por pares]United States: American Society for MicrobiologyTexto completo disponível |
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Material Type: Artigo
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Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial VirusMcLellan, Jason S. ; Chen, Man ; Joyce, M. Gordon ; Sastry, Mallika ; Stewart-Jones, Guillaume B. E. ; Yang, Yongping ; Zhang, Baoshan ; Chen, Lei ; Srivatsan, Sanjay ; Zheng, Anqi ; Zhou, Tongqing ; Graepel, Kevin W. ; Kumar, Azad ; Moin, Syed ; Boyington, Jeffrey C. ; Chuang, Gwo-Yu ; Soto, Cinque ; Baxa, Ulrich ; Bakker, Arjen Q. ; Spits, Hergen ; Beaumont, Tim ; Zheng, Zizheng ; Xia, Ningshao ; Ko, Sung-Youl ; Todd, John-Paul ; Rao, Srinivas ; Graham, Barney S. ; Kwong, Peter D.Science, 2013-11, Vol.342 (6158), p.592-598 [Periódico revisado por pares]United States: American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial VirusMarcandalli, Jessica ; Fiala, Brooke ; Ols, Sebastian ; Perotti, Michela ; de van der Schueren, Willem ; Snijder, Joost ; Hodge, Edgar ; Benhaim, Mark ; Ravichandran, Rashmi ; Carter, Lauren ; Sheffler, Will ; Brunner, Livia ; Lawrenz, Maria ; Dubois, Patrice ; Lanzavecchia, Antonio ; Sallusto, Federica ; Lee, Kelly K. ; Veesler, David ; Correnti, Colin E. ; Stewart, Lance J. ; Baker, David ; Loré, Karin ; Perez, Laurent ; King, Neil P.Cell, 2019-03, Vol.176 (6), p.1420-1431.e17 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Common Features of Enveloped Viruses and Implications for Immunogen Design for Next-Generation VaccinesRey, Felix A. ; Lok, Shee-MeiCell, 2018-03, Vol.172 (6), p.1319-1334 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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A proof of concept for structure-based vaccine design targeting RSV in humansCrank, Michelle C ; Ruckwardt, Tracy J ; Chen, Man ; Morabito, Kaitlyn M ; Phung, Emily ; Costner, Pamela J ; Holman, LaSonji A ; Hickman, Somia P ; Berkowitz, Nina M ; Gordon, Ingelise J ; Yamshchikov, Galina V ; Gaudinski, Martin R ; Kumar, Azad ; Chang, Lauren A ; Moin, Syed M ; Hill, Juliane P ; DiPiazza, Anthony T ; Schwartz, Richard M ; Kueltzo, Lisa ; Cooper, Jonathan W ; Chen, Peifeng ; Stein, Judith A ; Carlton, Kevin ; Gall, Jason G ; Nason, Martha C ; Kwong, Peter D ; Chen, Grace L ; Mascola, John R ; McLellan, Jason S ; Ledgerwood, Julie E ; Graham, Barney SScience (American Association for the Advancement of Science), 2019-08, Vol.365 (6452), p.505-509 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human seraNgwuta, Joan O ; Chen, Man ; Modjarrad, Kayvon ; Joyce, M Gordon ; Kanekiyo, Masaru ; Kumar, Azad ; Yassine, Hadi M ; Moin, Syed M ; Killikelly, April M ; Chuang, Gwo-Yu ; Druz, Aliaksandr ; Georgiev, Ivelin S ; Rundlet, Emily J ; Sastry, Mallika ; Stewart-Jones, Guillaume B E ; Yang, Yongping ; Zhang, Baoshan ; Nason, Martha C ; Capella, Cristina ; Peeples, Mark E ; Ledgerwood, Julie E ; McLellan, Jason S ; Kwong, Peter D ; Graham, Barney SScience translational medicine, 2015-10, Vol.7 (309), p.309ra162-309 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanismKrarup, Anders ; Truan, Daphné ; Furmanova-Hollenstein, Polina ; Bogaert, Lies ; Bouchier, Pascale ; Bisschop, Ilona J M ; Widjojoatmodjo, Myra N ; Zahn, Roland ; Schuitemaker, Hanneke ; McLellan, Jason S ; Langedijk, Johannes P MNat. Commun, 2015-09, Vol.6 (1), p.8143-8143, Article 8143 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
9 |
Material Type: Artigo
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Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing AntibodyMcLellan, Jason S. ; Chen, Man ; Leung, Sherman ; Graepel, Kevin W. ; Du, Xiulian ; Yang, Yongping ; Zhou, Tongqing ; Baxa, Ulrich ; Yasuda, Etsuko ; Beaumont, Tim ; Kumar, Azad ; Modjarrad, Kayvon ; Zheng, Zizheng ; Zhao, Min ; Xia, Ningshao ; Kwong, Peter D. ; Graham, Barney S.Science, 2013-05, Vol.340 (6136), p.1113-1117 [Periódico revisado por pares]United States: American Association for the Advancement of ScienceTexto completo disponível |
10 |
Material Type: Artigo
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Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibodyKong, Rui ; Xu, Kai ; Zhou, Tongqing ; Acharya, Priyamvada ; Lemmin, Thomas ; Liu, Kevin ; Ozorowski, Gabriel ; Soto, Cinque ; Taft, Justin D. ; Bailer, Robert T. ; Cale, Evan M. ; Chen, Lei ; Choi, Chang W. ; Chuang, Gwo-Yu ; Doria-Rose, Nicole A. ; Druz, Aliaksandr ; Georgiev, Ivelin S. ; Gorman, Jason ; Huang, Jinghe ; Joyce, M. Gordon ; Louder, Mark K. ; Ma, Xiaochu ; McKee, Krisha ; O'Dell, Sijy ; Pancera, Marie ; Yang, Yongping ; Blanchard, Scott C. ; Mothes, Walther ; Burton, Dennis R. ; Koff, Wayne C. ; Connors, Mark ; Ward, Andrew B. ; Kwong, Peter D. ; Mascola, John R.Science (American Association for the Advancement of Science), 2016-05, Vol.352 (6287), p.828-833 [Periódico revisado por pares]United States: American Association for the Advancement of ScienceTexto completo disponível |