U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies

Smith, Molly A ; Choudhary, Gaurav S ; Pellagatti, Andrea ; Choi, Kwangmin ; Bolanos, Lyndsey C ; Bhagat, Tushar D ; Gordon-Mitchell, Shanisha ; Von Ahrens, Dagny ; Pradhan, Kith ; Steeples, Violetta ; Kim, Sanghyun ; Steidl, Ulrich ; Walter, Matthew ; Fraser, Iain D C ; Kulkarni, Aishwarya ; Salomonis, Nathan ; Komurov, Kakajan ; Boultwood, Jacqueline ; Verma, Amit ; Starczynowski, Daniel T

England: Nature Publishing Group

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Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma

Shenoy, Niraj ; Bhagat, Tushar D ; Cheville, John ; Lohse, Christine ; Bhattacharyya, Sanchari ; Tischer, Alexander ; Machha, Venkata ; Gordon-Mitchell, Shanisha ; Choudhary, Gaurav ; Wong, Li-Fan ; Gross, LouAnn ; Ressigue, Emily ; Leibovich, Bradley ; Boorjian, Stephen A ; Steidl, Ulrich ; Wu, Xiaosheng ; Pradhan, Kith ; Gartrell, Benjamin ; Agarwal, Beamon ; Pagliaro, Lance ; Suzuki, Masako ; Greally, John M ; Rakheja, Dinesh ; Thompson, R Houston ; Susztak, Katalin ; Witzig, Thomas ; Zou, Yiyu ; Verma, Amit

United States: American Society for Clinical Investigation

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North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies

Shah, Urvi A. ; Chung, Elaine Y. ; Giricz, Orsi ; Pradhan, Kith ; Kataoka, Keisuke ; Gordon-Mitchell, Shanisha ; Bhagat, Tushar D. ; Mai, Yun ; Wei, Yongqiang ; Ishida, Elise ; Choudhary, Gaurav S. ; Joseph, Ancy ; Rice, Ronald ; Gitego, Nadege ; Parrish, Crystall ; Bartenstein, Matthias ; Goel, Swati ; Mantzaris, Ioannis ; Shastri, Aditi ; Derman, Olga ; Binder, Adam ; Gritsman, Kira ; Kornblum, Noah ; Braunschweig, Ira ; Bhagat, Chirag ; Hall, Jeff ; Graber, Armin ; Ratner, Lee ; Wang, Yanhua ; Ogawa, Seishi ; Verma, Amit ; Ye, B. Hilda ; Janakiram, Murali

United States: Elsevier Inc

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Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer

Zhang, Yang ; Chen, Xiaoyi ; Wang, Huamin ; Gordon-Mitchell, Shanisha ; Sahu, Srabani ; Bhagat, Tushar D ; Choudhary, Gaurav ; Aluri, Srinivas ; Pradhan, Kith ; Sahu, Plabani ; Carbajal, Milagros ; Zhang, Hui ; Agarwal, Beamon ; Shastri, Aditi ; Martell, Robert ; Starczynowski, Daniel ; Steidl, Ulrich ; Maitra, Anirban ; Verma, Amit

England: BioMed Central Ltd

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Correction: Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer

Zhang, Yang ; Chen, Xiaoyi ; Wang, Huamin ; Gordon-Mitchell, Shanisha ; Sahu, Srabani ; Bhagat, Tushar D ; Choudhary, Gaurav ; Aluri, Srinivas ; Pradhan, Kith ; Sahu, Plabani ; Carbajal, Milagros ; Zhang, Hui ; Agarwal, Beamon ; Shastri, Aditi ; Martell, Robert ; Starczynowski, Daniel ; Steidl, Ulrich ; Maitra, Anirban ; Verma, Amit

London: BioMed Central Ltd

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Inhibition of Toll-like Receptor 4 (TLR4) Promotes Erythroid and Myeloid Differentiation in Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Fromowitz, Ariel ; Aluri, Srinivas ; Gonzalez Lugo, Jesus D ; Rabinovich, Emma ; Ramachandra, Nandini ; Aminov, Sarah ; Sahu, Srabani ; Gordon Mitchell, Shanisha ; Aggarwal, Ritesh ; Ajibade, Opeyemi ; Carbajal, Milagros ; Pradhan, Kith ; Pellagatti, Andrea ; Boultwood, Jacqueline ; Shastri, Aditi ; Zhao, Rongbao ; Verma, Amit K.

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Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts

Bhagat, Tushar D ; Von Ahrens, Dagny ; Dawlaty, Meelad ; Zou, Yiyu ; Baddour, Joelle ; Achreja, Abhinav ; Zhao, Hongyun ; Yang, Lifeng ; Patel, Brijesh ; Kwak, Changsoo ; Choudhary, Gaurav S ; Gordon-Mitchell, Shanisha ; Aluri, Srinivas ; Bhattacharyya, Sanchari ; Sahu, Srabani ; Bhagat, Prafulla ; Yu, Yiting ; Bartenstein, Matthias ; Giricz, Orsi ; Suzuki, Masako ; Sohal, Davendra ; Gupta, Sonal ; Guerrero, Paola A ; Batra, Surinder ; Goggins, Michael ; Steidl, Ulrich ; Greally, John ; Agarwal, Beamon ; Pradhan, Kith ; Banerjee, Debabrata ; Nagrath, Deepak ; Maitra, Anirban ; Verma, Amit

England: eLife Sciences Publications Ltd

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Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells

Shastri, Aditi ; Choudhary, Gaurav ; Teixeira, Margarida ; Gordon-Mitchell, Shanisha ; Ramachandra, Nandini ; Bernard, Lumie ; Bhattacharyya, Sanchari ; Lopez, Robert ; Pradhan, Kith ; Giricz, Orsolya ; Ravipati, Goutham ; Wong, Li-Fan ; Cole, Sally ; Bhagat, Tushar D ; Feld, Jonathan ; Dhar, Yosman ; Bartenstein, Matthias ; Thiruthuvanathan, Victor J ; Wickrema, Amittha ; Ye, B Hilda ; Frank, David A ; Pellagatti, Andrea ; Boultwood, Jacqueline ; Zhou, Tianyuan ; Kim, Youngsoo ; MacLeod, A Robert ; Epling-Burnette, P K ; Ye, Minwei ; McCoon, Patricia ; Woessner, Richard ; Steidl, Ulrich ; Will, Britta ; Verma, Amit

United States: American Society for Clinical Investigation

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Immunotherapy-resistant acute lymphoblastic leukemia cells exhibit reduced CD19 and CD22 expression and BTK pathway dependency

Aminov, Sarah ; Ciriez, Orsi ; Melnekoff, David T ; Sica, R Alejandro ; Polishchuk, Veronika ; Papazoglu, Cristian ; Yates, Bonnie ; Wang, Hao-Wei ; Sahu, Srabani ; Wang, Yanhua ; Gordon-Mitchell, Shanisha ; Leshchenko, Violetta V ; Schinke, Carolina ; Pradhan, Kith ; Aluri, Srinivas ; Sohn, Moah ; Barta, Stefan K ; Agarwal, Beamon ; Goldfinger, Mendel ; Mantzaris, Ioannis ; Shastri, Aditi ; Matsui, William ; Steidl, Ulrich ; Brody, Joshua D ; Shah, Nirali N ; Parekh, Samir ; Verma, Amit

Ann Arbor: American Society for Clinical Investigation

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Abstract PO-045: Interleukin 1 receptor accessory protein (IL1RAP) in novel targetable pathway in pancreatic cancer

Zhang, Yang ; Chen, Xiaoyi ; Gordon-Mitchell, Shanisha ; Pradhan, Kith ; Choudhary, Gaurav ; Bhagat, Tushar D. ; Agarwal, Beamon ; Steidl, Ulrich ; Maitra, Anirban ; Verma, Amit

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