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AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity
AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity
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AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity

Saliba, Soraya Wilke ; Marcotegui, Ariel R ; Fortwängler, Ellen ; Ditrich, Johannes ; Perazzo, Juan Carlos ; Muñoz, Eduardo ; de Oliveira, Antônio Carlos Pinheiro ; Fiebich, Bernd L

Journal of neuroinflammation, 2017-12, Vol.14 (1), p.246-246, Article 246 [Periódico revisado por pares]

England: BioMed Central

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2
Memory Consolidation Depends on Endogenous Hippocampal Levels of Anandamide: CB1 and M4, but Possibly not TRPV1 Receptors Mediate AM404 effects
Memory Consolidation Depends on Endogenous Hippocampal Levels of Anandamide: CB1 and M4, but Possibly not TRPV1 Receptors Mediate AM404 effects
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Memory Consolidation Depends on Endogenous Hippocampal Levels of Anandamide: CB1 and M4, but Possibly not TRPV1 Receptors Mediate AM404 effects

Scienza-Martin, Krislei ; Lotz, Fernanda Nogueira ; Zanona, Querusche Klippel ; Santana-Kragelund, Fabiana ; Crestani, Ana Paula ; Boos, Flávia Zacouteguy ; Calcagnotto, Maria Elisa ; Quillfeldt, Jorge Alberto

Neuroscience, 2022-08, Vol.497, p.53-72 [Periódico revisado por pares]

United States: Elsevier Ltd

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3
Synthesis of Acetaminophen Analogues Containing α-Amino Acids and Fatty Acids for Inhibiting Hepatotoxicity
Synthesis of Acetaminophen Analogues Containing α-Amino Acids and Fatty Acids for Inhibiting Hepatotoxicity
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Synthesis of Acetaminophen Analogues Containing α-Amino Acids and Fatty Acids for Inhibiting Hepatotoxicity

Jung, Seunghee ; Kawashima, Yuya ; Noguchi, Takuya ; Imai, Nobuyuki

Synthesis (Stuttgart), 2019-10, Vol.51 (19), p.3683-3696 [Periódico revisado por pares]

Stuttgart · New York: Georg Thieme Verlag

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4
N-arachidonoylphenolamine alleviates ischaemia/reperfusion-induced cardiomyocyte necroptosis by restoring proteasomal activity
N-arachidonoylphenolamine alleviates ischaemia/reperfusion-induced cardiomyocyte necroptosis by restoring proteasomal activity
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N-arachidonoylphenolamine alleviates ischaemia/reperfusion-induced cardiomyocyte necroptosis by restoring proteasomal activity

Bai, Jun-Qin ; Li, Pang-Bo ; Li, Chun-Min ; Li, Hui-Hua

European journal of pharmacology, 2024-01, Vol.963, p.176235-176235, Article 176235 [Periódico revisado por pares]

Netherlands

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5
An Updated Review on the Metabolite (AM404)-Mediated Central Mechanism of Action of Paracetamol (Acetaminophen): Experimental Evidence and Potential Clinical Impact
An Updated Review on the Metabolite (AM404)-Mediated Central Mechanism of Action of Paracetamol (Acetaminophen): Experimental Evidence and Potential Clinical Impact
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An Updated Review on the Metabolite (AM404)-Mediated Central Mechanism of Action of Paracetamol (Acetaminophen): Experimental Evidence and Potential Clinical Impact

Mallet, Christophe ; Desmeules, Jules ; Pegahi, Rassa ; Eschalier, Alain

Journal of pain research, 2023-01, Vol.16, p.1081-1094 [Periódico revisado por pares]

New Zealand: Dove Medical Press Limited

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6
Oral acetaminophen-induced spinal 5-hydroxytriyptamine release produces analgesic effects in the rat formalin test
Oral acetaminophen-induced spinal 5-hydroxytriyptamine release produces analgesic effects in the rat formalin test
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Oral acetaminophen-induced spinal 5-hydroxytriyptamine release produces analgesic effects in the rat formalin test

Nakamura, Shingo ; Nonaka, Takahiro ; Komatsu, Shuji ; Yamada, Toshihiko ; Yamamoto, Tatsuo

Biomedicine & pharmacotherapy, 2022-02, Vol.146, p.112578-112578, Article 112578 [Periódico revisado por pares]

France: Elsevier Masson SAS

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7
Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism
Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism
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Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism

Rehfeld, A ; Frederiksen, H ; Rasmussen, R H ; David, A ; Chaker, J ; Nielsen, B S ; Nielsen, J E ; Juul, A ; Skakkebæk, N E ; Kristensen, D M

Human reproduction (Oxford), 2022-05, Vol.37 (5), p.922-935 [Periódico revisado por pares]

England: Oxford University Press (OUP)

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8
2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons
2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons
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2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons

Llorente-Berzal, Alvaro ; Terzian, Ana Luisa B. ; di Marzo, Vincenzo ; Micale, Vincenzo ; Viveros, Maria Paz ; Wotjak, Carsten T.

Psychopharmacology, 2015-08, Vol.232 (15), p.2811-2825 [Periódico revisado por pares]

Berlin/Heidelberg: Springer Berlin Heidelberg

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9
Extinction of avoidance behavior by safety learning depends on endocannabinoid signaling in the hippocampus
Extinction of avoidance behavior by safety learning depends on endocannabinoid signaling in the hippocampus
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Extinction of avoidance behavior by safety learning depends on endocannabinoid signaling in the hippocampus

Micale, Vincenzo ; Stepan, Jens ; Jurik, Angela ; Pamplona, Fabricio A ; Marsch, Rudolph ; Drago, Filippo ; Eder, Matthias ; Wotjak, Carsten T

Journal of psychiatric research, 2017-07, Vol.90, p.46-59 [Periódico revisado por pares]

England: Elsevier Ltd

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10
Anti-Inflammatory and Anti-Oxidative Effects of AM404 in IL-1β-Stimulated SK-N-SH Neuroblastoma Cells
Anti-Inflammatory and Anti-Oxidative Effects of AM404 in IL-1β-Stimulated SK-N-SH Neuroblastoma Cells
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Anti-Inflammatory and Anti-Oxidative Effects of AM404 in IL-1β-Stimulated SK-N-SH Neuroblastoma Cells

Apweiler, Matthias ; Streyczek, Jana ; Saliba, Soraya Wilke ; Ditrich, Johannes ; Muñoz, Eduardo ; Fiebich, Bernd L.

Frontiers in pharmacology, 2021-11, Vol.12, p.789074-789074 [Periódico revisado por pares]

Frontiers Media S.A

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