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Fusion protein linkers: Property, design and functionality
Fusion protein linkers: Property, design and functionality
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Fusion protein linkers: Property, design and functionality

Chen, Xiaoying ; Zaro, Jennica L. ; Shen, Wei-Chiang

Advanced drug delivery reviews, 2013-10, Vol.65 (10), p.1357-1369 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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2
Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension
Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension
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Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension

Hoeper, Marius M. ; Badesch, David B. ; Ghofrani, H. Ardeschir ; Gibbs, J. Simon R. ; Gomberg-Maitland, Mardi ; McLaughlin, Vallerie V. ; Preston, Ioana R. ; Souza, Rogerio ; Waxman, Aaron B. ; Grünig, Ekkehard ; Kopeć, Grzegorz ; Meyer, Gisela ; Olsson, Karen M. ; Rosenkranz, Stephan ; Xu, Yayun ; Miller, Barry ; Fowler, Marcie ; Butler, John ; Koglin, Joerg ; de Oliveira Pena, Janethe ; Humbert, Marc

The New England journal of medicine, 2023-04, Vol.388 (16), p.1478-1490 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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3
Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials
Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials
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Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials

Abreu, Francis ; Adamis, Anthony P ; Eichenbaum, David A ; Haskova, Zdenka ; Lin, Hugh ; Loewenstein, Anat ; Mohan, Shaun ; Wells, John A ; Willis, Jeffrey R ; Aaberg, Thomas ; Alam, Suhail ; Amini, Payam ; Antoszyk, Andrew ; Asaria, Riaz ; Avila, Marcos ; Awh, Carl C ; Bafalluy, Joaquin ; Bator, Gyorgy ; Burgess, Stuart ; Calzada, Jorge ; Campochiaro, Peter ; Chang, Jonathan ; Chaudhry, Nauman ; Chee, Caroline ; Chittum, Mark ; Chow, David ; Cornut, Pierre Loic ; Eldem, Bora ; Ernest, Jan ; Feiner, Leonard ; Fernandez, Carlos ; Ferrone, Philip ; Figueroa, Marta ; Fine, Howard ; Foxman, Scott ; Fung, Nicholas ; Garcia-Layana, Alfredo ; Gawecki, Maciej ; Ghanchi, Faruque ; Goldberg, Roger ; Gonzalez, Victor ; Higgins, Patrick ; Ho, Allen ; Holekamp, Nancy ; Hsu, Jason ; Ikeda, Yasuhiro ; Jhaveri, Chirag ; Kapoor, Kapil ; Kerenyi, Agnes ; Khanani, Arshad ; Kitano, Shigehiko ; Korobelnik, Jean Francois ; Lalonde, Laurent ; Larsen, Michael ; Laugesen, Caroline ; Lebreton, Olivier ; Lee, Seong ; Liu, Mimi ; Lorenz, Katrin ; Lozano Rechy, David ; Margherio, Alan ; Menon, Geeta ; Michalska-Malecka, Katarzyna ; Morori-Katz, Haia ; Newell, Charles ; Nicolo, Massimo ; Nielsen, Jared ; Osher, James ; Papp, Andras ; Pearce, Ian ; Pertile, Grazia ; Raskauskas, Paul ; Razavi, Hessam ; Rosenblatt, Brett ; Sandner, Dirk ; Sermet, Figen ; Shah, Sandeep ; Sharma, Sumit ; Spital, Georg ; Stern, Jeffrey ; Stone, Cameron ; Stone, Amy ; Sun, Jennifer ; Szalczer, Lajos ; Szecsko, Timea ; Tadayoni, Ramin ; Talks, James ; Tanabe, Teruyo ; Torti, Robert ; Tosheva Guneva, Daniela ; Varma, Deepali ; Vassileva, Petja ; Weber, Pamela ; Wells, John A ; Williams, Thomas ; Wykoff, Charles C ; Yilmaz, Gursel ; Yiu, Glenn ; Yurieva, Tatiana ; Zatorska, Barbara

The Lancet (British edition), 2022-02, Vol.399 (10326), p.741-755 [Periódico revisado por pares]

England: Elsevier Ltd

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4
Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials
Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials
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Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials

Heier, Jeffrey S ; Patel, Vaibhavi ; Viola, Francesco ; Adan Civera, Alfredo ; Agostini, Hansjurgen ; Almony, Arghavan ; Antoszyk, Andrew ; Awh, Carl C. ; Brown, Jamin ; Budzinskaya, Maria ; Buffet, Sylvia ; Byon, Iksoo ; Calzada, Jorge ; Carneiro, Angela ; Chao, Daniel ; Chen, Shih-Jen ; Cheung, Gemmy ; Chexal, Saradha ; Chittum, Mark ; Cornut, Pierre Loic ; Dessouki, Amr ; Dolz, Rosa ; Eldem, Bora ; Escobar, Joan Josep ; Falk, Naomi ; Feiner, Leonard ; Fernandez Vega, Alvaro ; Figueroa, Marta ; Fine, Howard ; Franco, Pablo ; Fraser-Bell, Samantha ; Furno Sola, Federico ; Giunta, Michel ; Gomez Ulla, Francisco ; Gupta, Sunil ; Guthoff, Rainer ; Guymer, Robyn ; Hampton, Robert ; Hayashi, Ken ; Heier, Jeffrey ; Howard, James ; Hu, Allen ; Imaizumi, Hiroko ; Javey, Golnaz ; Javid, Cameron ; Klein-Mascia, Kendra ; Kobayashi, Namie ; Kodjikian, Laurent ; Kulikov, Alexey ; Kwong, Henry ; Kwun, Robert ; Lai, Timothy ; Lai, Chi-Chun ; Lalonde, Laurent ; Lanzetta, Paolo ; Lee, ji Eun ; Lindsell, Lucas ; London, Nikolas ; Lotery, Andrew ; Lozano Rechy, David ; Margherio, Alan ; Masse, Helene ; Michels, Mark ; Mohamed, Quresh ; Montero, Javier ; Morori-Katz, Haia ; Murata, Toshinori ; Muzyka-Wozniak, Maria ; Oleksy, Piotr ; Patel, Apurva ; Pauleikhoff, Daniel ; Pearce, Ian ; Qureshi, Jawad ; Razavi, Hessam ; Reilly, Gayatri ; Saedon, Habiba ; Saeed, Usman ; Sararols, Laura ; Schadlu, Ramin ; Schlottmann, Patricio ; Sekiryu, Tetsuju ; Seres, András ; Sheidow, Thomas ; Sikorski, Bartosz ; Singerman, Lawrence ; Souied, Eric ; Steinmetz, Robert ; Stoller, Glenn ; Taleb, Alexandre ; Tran, Khoi ; Vajas, Attila ; Virgili, Gianni ; Weber, Pamela ; Wells, John A. ; Williams, Thomas ; Yilmaz, Gursel ; Yiu, Glenn ; Yoneda, Ai ; Yoon, Young Hee ; Zeolite, Carlos

The Lancet (British edition), 2022-02, Vol.399 (10326), p.729-740 [Periódico revisado por pares]

England: Elsevier Ltd

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5
Synthetic Self-Assembling Clostridial Chimera for Modulation of Sensory Functions
Synthetic Self-Assembling Clostridial Chimera for Modulation of Sensory Functions
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Synthetic Self-Assembling Clostridial Chimera for Modulation of Sensory Functions

Ferrari, Enrico ; Gu, Chunjing ; Niranjan, Dhevahi ; Restani, Laura ; Rasetti-Escargueil, Christine ; Obara, Ilona ; Geranton, Sandrine M ; Arsenault, Jason ; Goetze, Tom A ; Harper, Callista B ; Nguyen, Tam H ; Maywood, Elizabeth ; O’Brien, John ; Schiavo, Giampietro ; Wheeler, Daniel W ; Meunier, Frederic A ; Hastings, Michael ; Edwardson, J. Michael ; Sesardic, Dorothea ; Caleo, Matteo ; Hunt, Stephen P ; Davletov, Bazbek

Bioconjugate chemistry, 2013-10, Vol.24 (10), p.1750-1759 [Periódico revisado por pares]

United States: American Chemical Society

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6
An Open‐Label, Dose‐Escalation Study to Assess the Safety and Efficacy of IL‐22 Agonist F‐652 in Patients With Alcohol‐associated Hepatitis
An Open‐Label, Dose‐Escalation Study to Assess the Safety and Efficacy of IL‐22 Agonist F‐652 in Patients With Alcohol‐associated Hepatitis
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An Open‐Label, Dose‐Escalation Study to Assess the Safety and Efficacy of IL‐22 Agonist F‐652 in Patients With Alcohol‐associated Hepatitis

Arab, Juan P. ; Sehrawat, Tejasav S. ; Simonetto, Douglas A. ; Verma, Vikas K. ; Feng, Dechun ; Tang, Tom ; Dreyer, Kevin ; Yan, Xiaoqiang ; Daley, William L. ; Sanyal, Arun ; Chalasani, Naga ; Radaeva, Svetlana ; Yang, Liu ; Vargas, Hugo ; Ibacache, Mauricio ; Gao, Bin ; Gores, Gregory J. ; Malhi, Harmeet ; Kamath, Patrick S. ; Shah, Vijay H.

Hepatology (Baltimore, Md.), 2020-08, Vol.72 (2), p.441-453 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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7
Aflibercept, Bevacizumab, or Ranibizumab for Diabetic Macular Edema
Aflibercept, Bevacizumab, or Ranibizumab for Diabetic Macular Edema
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Aflibercept, Bevacizumab, or Ranibizumab for Diabetic Macular Edema

Wells, John A ; Glassman, Adam R ; Ayala, Allison R ; Jampol, Lee M ; Aiello, Lloyd Paul ; Antoszyk, Andrew N ; Arnold-Bush, Bambi ; Baker, Carl W ; Bressler, Neil M ; Browning, David J ; Elman, Michael J ; Ferris, Frederick L ; Friedman, Scott M ; Melia, Michele ; Pieramici, Dante J ; Sun, Jennifer K ; Beck, Roy W

The New England journal of medicine, 2015-03, Vol.372 (13), p.1193-1203 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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8
Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm
Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm
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Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm

Pemmaraju, Naveen ; Lane, Andrew A ; Sweet, Kendra L ; Stein, Anthony S ; Vasu, Sumithira ; Blum, William ; Rizzieri, David A ; Wang, Eunice S ; Duvic, Madeleine ; Sloan, J. Mark ; Spence, Sharon ; Shemesh, Shay ; Brooks, Christopher L ; Balser, John ; Bergstein, Ivan ; Lancet, Jeffrey E ; Kantarjian, Hagop M ; Konopleva, Marina

The New England journal of medicine, 2019-04, Vol.380 (17), p.1628-1637 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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9
Hepatotoxicity following administration of onasemnogene abeparvovec (AVXS-101) for the treatment of spinal muscular atrophy
Hepatotoxicity following administration of onasemnogene abeparvovec (AVXS-101) for the treatment of spinal muscular atrophy
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Hepatotoxicity following administration of onasemnogene abeparvovec (AVXS-101) for the treatment of spinal muscular atrophy

Chand, Deepa ; Mohr, Franziska ; McMillan, Hugh ; Tukov, Francis Fonyuy ; Montgomery, Kyle ; Kleyn, Aaron ; Sun, Rui ; Tauscher-Wisniewski, Sitra ; Kaufmann, Petra ; Kullak-Ublick, Gerd

Journal of hepatology, 2021-03, Vol.74 (3), p.560-566 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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10
A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors
A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors
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A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors

Jimeno, Antonio ; Gordon, Michael ; Chugh, Rashmi ; Messersmith, Wells ; Mendelson, David ; Dupont, Jakob ; Stagg, Robert ; Kapoun, Ann M ; Xu, Lu ; Uttamsingh, Shailaja ; Brachmann, Rainer K ; Smith, David C

Clinical cancer research, 2017-12, Vol.23 (24), p.7490-7497 [Periódico revisado por pares]

United States: American Association for Cancer Research Inc

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