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1
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

Shi, Hubing ; Sazegar, Hooman ; Nazarian, Ramin ; Chodon, Thinle ; Lee, Hane ; Sosman, Jeffrey A ; Lo, Roger S ; Koya, Richard C ; Lee, Mi-Kyung ; Attar, Narsis ; Kong, Xiangju ; Nelson, Stanley F ; Ribas, Antoni ; Chen, Zugen ; McArthur, Grant ; Wang, Qi

Nature (London), 2010-12, Vol.468 (7326), p.973-977 [Periódico revisado por pares]

London: Nature Publishing Group

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2
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
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Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

Gay, Carl M. ; Stewart, C. Allison ; Park, Elizabeth M. ; Diao, Lixia ; Groves, Sarah M. ; Heeke, Simon ; Nabet, Barzin Y. ; Fujimoto, Junya ; Solis, Luisa M. ; Lu, Wei ; Xi, Yuanxin ; Cardnell, Robert J. ; Wang, Qi ; Fabbri, Giulia ; Cargill, Kasey R. ; Vokes, Natalie I. ; Ramkumar, Kavya ; Zhang, Bingnan ; Della Corte, Carminia M. ; Robson, Paul ; Swisher, Stephen G. ; Roth, Jack A. ; Glisson, Bonnie S. ; Shames, David S. ; Wistuba, Ignacio I. ; Wang, Jing ; Quaranta, Vito ; Minna, John ; Heymach, John V. ; Byers, Lauren Averett

Cancer cell, 2021-03, Vol.39 (3), p.346-360.e7 [Periódico revisado por pares]

United States: Elsevier Inc

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3
PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer
PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer
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PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer

Chabanon, Roman M ; Morel, Daphné ; Eychenne, Thomas ; Colmet-Daage, Léo ; Bajrami, Ilirjana ; Dorvault, Nicolas ; Garrido, Marlène ; Meisenberg, Cornelia ; Lamb, Andrew ; Ngo, Carine ; Hopkins, Suzanna R ; Roumeliotis, Theodoros I ; Jouny, Samuel ; Hénon, Clémence ; Kawai-Kawachi, Asuka ; Astier, Clémence ; Konde, Asha ; Del Nery, Elaine ; Massard, Christophe ; Pettitt, Stephen J ; Margueron, Raphaël ; Choudhary, Jyoti S ; Almouzni, Geneviève ; Soria, Jean-Charles ; Deutsch, Eric ; Downs, Jessica A ; Lord, Christopher J ; Postel-Vinay, Sophie

Cancer research (Chicago, Ill.), 2021-06, Vol.81 (11), p.2888-2902 [Periódico revisado por pares]

United States: American Association for Cancer Research

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4
miR-508-5p regulates multidrug resistance of gastric cancer by targeting ABCB1 and ZNRD1
miR-508-5p regulates multidrug resistance of gastric cancer by targeting ABCB1 and ZNRD1
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miR-508-5p regulates multidrug resistance of gastric cancer by targeting ABCB1 and ZNRD1

Shang, Y ; Zhang, Z ; Liu, Z ; Feng, B ; Ren, G ; Li, K ; Zhou, L ; Sun, Y ; Li, M ; Zhou, J ; An, Y ; Wu, K ; Nie, Y ; Fan, D

Oncogene, 2014-06, Vol.33 (25), p.3267-3276 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents
Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents
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Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

Merlevede, Jane ; Droin, Nathalie ; Qin, Tingting ; Meldi, Kristen ; Yoshida, Kenichi ; Morabito, Margot ; Chautard, Emilie ; Auboeuf, Didier ; Fenaux, Pierre ; Braun, Thorsten ; Itzykson, Raphael ; de Botton, Stéphane ; Quesnel, Bruno ; Commes, Thérèse ; Jourdan, Eric ; Vainchenker, William ; Bernard, Olivier ; Pata-Merci, Noemie ; Solier, Stéphanie ; Gayevskiy, Velimir ; Dinger, Marcel E ; Cowley, Mark J ; Selimoglu-Buet, Dorothée ; Meyer, Vincent ; Artiguenave, François ; Deleuze, Jean-François ; Preudhomme, Claude ; Stratton, Michael R ; Alexandrov, Ludmil B ; Padron, Eric ; Ogawa, Seishi ; Koscielny, Serge ; Figueroa, Maria ; Solary, Eric

Nature communications, 2016-02, Vol.7 (1), p.10767-10767, Article 10767 [Periódico revisado por pares]

England: Nature Publishing Group

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6
Pembrolizumab monotherapy for previously untreated, PD-L1-positive, metastatic triple-negative breast cancer: cohort B of the phase II KEYNOTE-086 study
Pembrolizumab monotherapy for previously untreated, PD-L1-positive, metastatic triple-negative breast cancer: cohort B of the phase II KEYNOTE-086 study
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Pembrolizumab monotherapy for previously untreated, PD-L1-positive, metastatic triple-negative breast cancer: cohort B of the phase II KEYNOTE-086 study

Adams, S. ; Loi, S. ; Toppmeyer, D. ; Cescon, D.W. ; De Laurentiis, M. ; Nanda, R. ; Winer, E.P. ; Mukai, H. ; Tamura, K. ; Armstrong, A. ; Liu, M.C. ; Iwata, H. ; Ryvo, L. ; Wimberger, P. ; Rugo, H.S. ; Tan, A.R. ; Jia, L. ; Ding, Y. ; Karantza, V. ; Schmid, P.

Annals of oncology, 2019-03, Vol.30 (3), p.405-411 [Periódico revisado por pares]

England: Elsevier Ltd

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7
Squalene epoxidase as a promising metabolic target in cancer treatment
Squalene epoxidase as a promising metabolic target in cancer treatment
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Squalene epoxidase as a promising metabolic target in cancer treatment

Cirmena, Gabriella ; Franceschelli, Paola ; Isnaldi, Edoardo ; Ferrando, Lorenzo ; De Mariano, Marilena ; Ballestrero, Alberto ; Zoppoli, Gabriele

Cancer letters, 2018-07, Vol.425, p.13-20 [Periódico revisado por pares]

Ireland: Elsevier B.V

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8
Pembrolizumab monotherapy for previously treated metastatic triple-negative breast cancer: cohort A of the phase II KEYNOTE-086 study
Pembrolizumab monotherapy for previously treated metastatic triple-negative breast cancer: cohort A of the phase II KEYNOTE-086 study
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Pembrolizumab monotherapy for previously treated metastatic triple-negative breast cancer: cohort A of the phase II KEYNOTE-086 study

Adams, S. ; Schmid, P. ; Rugo, H.S. ; Winer, E.P. ; Loirat, D. ; Awada, A. ; Cescon, D.W. ; Iwata, H. ; Campone, M. ; Nanda, R. ; Hui, R. ; Curigliano, G. ; Toppmeyer, D. ; O’Shaughnessy, J. ; Loi, S. ; Paluch-Shimon, S. ; Tan, A.R. ; Card, D. ; Zhao, J. ; Karantza, V. ; Cortés, J.

Annals of oncology, 2019-03, Vol.30 (3), p.397-404 [Periódico revisado por pares]

England: Elsevier Ltd

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9
Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11
Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11
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Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11

Lang, Xueting ; Green, Michael D ; Wang, Weimin ; Yu, Jiali ; Choi, Jae Eun ; Jiang, Long ; Liao, Peng ; Zhou, Jiajia ; Zhang, Qiang ; Dow, Ania ; Saripalli, Anjali L ; Kryczek, Ilona ; Wei, Shuang ; Szeliga, Wojciech ; Vatan, Linda ; Stone, Everett M ; Georgiou, George ; Cieslik, Marcin ; Wahl, Daniel R ; Morgan, Meredith A ; Chinnaiyan, Arul M ; Lawrence, Theodore S ; Zou, Weiping

Cancer discovery, 2019-12, Vol.9 (12), p.1673-1685

United States

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10
A selective BCL-X L PROTAC degrader achieves safe and potent antitumor activity
A selective BCL-X L PROTAC degrader achieves safe and potent antitumor activity
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A selective BCL-X L PROTAC degrader achieves safe and potent antitumor activity

Khan, Sajid ; Zhang, Xuan ; Lv, Dongwen ; Zhang, Qi ; He, Yonghan ; Zhang, Peiyi ; Liu, Xingui ; Thummuri, Dinesh ; Yuan, Yaxia ; Wiegand, Janet S ; Pei, Jing ; Zhang, Weizhou ; Sharma, Abhisheak ; McCurdy, Christopher R ; Kuruvilla, Vinitha M ; Baran, Natalia ; Ferrando, Adolfo A ; Kim, Yong-Mi ; Rogojina, Anna ; Houghton, Peter J ; Huang, Guangcun ; Hromas, Robert ; Konopleva, Marina ; Zheng, Guangrong ; Zhou, Daohong

Nature medicine, 2019-12, Vol.25 (12), p.1938 [Periódico revisado por pares]

United States

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