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Rapid modelling of cooperating genetic events in cancer through somatic genome editing
Rapid modelling of cooperating genetic events in cancer through somatic genome editing
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Rapid modelling of cooperating genetic events in cancer through somatic genome editing

Sánchez-Rivera, Francisco J ; Papagiannakopoulos, Thales ; Romero, Rodrigo ; Tammela, Tuomas ; Bauer, Matthew R ; Bhutkar, Arjun ; Joshi, Nikhil S ; Subbaraj, Lakshmipriya ; Bronson, Roderick T ; Xue, Wen ; Jacks, Tyler

Nature (London), 2014-12, Vol.516 (7531), p.428-431 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Optimized base editors enable efficient editing in cells, organoids and mice
Optimized base editors enable efficient editing in cells, organoids and mice
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Optimized base editors enable efficient editing in cells, organoids and mice

Zafra, Maria Paz ; Schatoff, Emma M ; Katti, Alyna ; Foronda, Miguel ; Breinig, Marco ; Schweitzer, Anabel Y ; Simon, Amber ; Han, Teng ; Goswami, Sukanya ; Montgomery, Emma ; Thibado, Jordana ; Kastenhuber, Edward R ; Sánchez-Rivera, Francisco J ; Shi, Junwei ; Vakoc, Christopher R ; Lowe, Scott W ; Tschaharganeh, Darjus F ; Dow, Lukas E

Nature biotechnology, 2018-10, Vol.36 (9), p.888-893 [Periódico revisado por pares]

United States: Nature Publishing Group

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3
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
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Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

Hoffmann, H.-Heinrich ; Sánchez-Rivera, Francisco J. ; Schneider, William M. ; Luna, Joseph M. ; Soto-Feliciano, Yadira M. ; Ashbrook, Alison W. ; Le Pen, Jérémie ; Leal, Andrew A. ; Ricardo-Lax, Inna ; Michailidis, Eleftherios ; Hao, Yuan ; Stenzel, Ansgar F. ; Peace, Avery ; Zuber, Johannes ; Allis, C. David ; Lowe, Scott W. ; MacDonald, Margaret R. ; Poirier, John T. ; Rice, Charles M.

Cell host & microbe, 2021-02, Vol.29 (2), p.267-280.e5 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Targeting the De Novo Purine Synthesis Pathway Through Adenylosuccinate Lyase Depletion Impairs Liver Cancer Growth by Perturbing Mitochondrial Function
Targeting the De Novo Purine Synthesis Pathway Through Adenylosuccinate Lyase Depletion Impairs Liver Cancer Growth by Perturbing Mitochondrial Function
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Targeting the De Novo Purine Synthesis Pathway Through Adenylosuccinate Lyase Depletion Impairs Liver Cancer Growth by Perturbing Mitochondrial Function

Jiang, Tingting ; Sánchez‐Rivera, Francisco J. ; Soto‐Feliciano, Yadira M. ; Yang, Qiyuan ; Song, Chun‐Qing ; Bhuatkar, Arjun ; Haynes, Cole M ; Hemann, Michael T. ; Xue, Wen

Hepatology (Baltimore, Md.), 2021-07, Vol.74 (1), p.233-247 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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5
SOAT1 promotes mevalonate pathway dependency in pancreatic cancer
SOAT1 promotes mevalonate pathway dependency in pancreatic cancer
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SOAT1 promotes mevalonate pathway dependency in pancreatic cancer

Oni, Tobiloba E ; Biffi, Giulia ; Baker, Lindsey A ; Hao, Yuan ; Tonelli, Claudia ; Somerville, Tim D D ; Deschênes, Astrid ; Belleau, Pascal ; Hwang, Chang-Il ; Sánchez-Rivera, Francisco J ; Cox, Hilary ; Brosnan, Erin ; Doshi, Abhishek ; Lumia, Rebecca P ; Khaledi, Kimia ; Park, Youngkyu ; Trotman, Lloyd C ; Lowe, Scott W ; Krasnitz, Alexander ; Vakoc, Christopher R ; Tuveson, David A

The Journal of experimental medicine, 2020-09, Vol.217 (9) [Periódico revisado por pares]

United States: Rockefeller University Press

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6
Phase and context shape the function of composite oncogenic mutations
Phase and context shape the function of composite oncogenic mutations
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Phase and context shape the function of composite oncogenic mutations

Gorelick, Alexander N ; Sánchez-Rivera, Francisco J ; Cai, Yanyan ; Bielski, Craig M ; Biederstedt, Evan ; Jonsson, Philip ; Richards, Allison L ; Vasan, Neil ; Penson, Alexander V ; Friedman, Noah D ; Ho, Yu-Jui ; Baslan, Timour ; Bandlamudi, Chaitanya ; Scaltriti, Maurizio ; Schultz, Nikolaus ; Lowe, Scott W ; Reznik, Ed ; Taylor, Barry S

Nature (London), 2020-06, Vol.582 (7810), p.100-103 [Periódico revisado por pares]

England: Nature Publishing Group

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7
Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis
Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis
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Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis

Leibold, Josef ; Ruscetti, Marcus ; Cao, Zhen ; Ho, Yu-Jui ; Baslan, Timour ; Zou, Min ; Abida, Wassim ; Feucht, Judith ; Han, Teng ; Barriga, Francisco M ; Tsanov, Kaloyan M ; Zamechek, Leah ; Kulick, Amanda ; Amor, Corina ; Tian, Sha ; Rybczyk, Katarzyna ; Salgado, Nelson R ; Sanchez-Rivera, Francisco J ; Watson, Philip A ; de Stanchina, Elisa ; Wilkinson, John E ; Dow, Lukas E ; Abate-Shen, Cory ; Sawyers, Charles L ; Lowe, Scott W

Cancer discovery, 2020-07, Vol.10 (7), p.1038-1057

United States

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8
A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1
A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1
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A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1

Loizou, Evangelia ; Banito, Ana ; Livshits, Geulah ; Ho, Yu-Jui ; Koche, Richard P ; Sánchez-Rivera, Francisco J ; Mayle, Allison ; Chen, Chi-Chao ; Kinalis, Savvas ; Bagger, Frederik O ; Kastenhuber, Edward R ; Durham, Benjamin H ; Lowe, Scott W

Cancer discovery, 2019-07, Vol.9 (7), p.962-979

United States

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9
Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma
Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma
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Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma

Chen, Xiao ; Li, Yinglu ; Zhu, Fang ; Xu, Xinjing ; Estrella, Brian ; Pazos, 2nd, Manuel A ; McGuire, John T ; Karagiannis, Dimitris ; Sahu, Varun ; Mustafokulov, Mustafo ; Scuoppo, Claudio ; Sánchez-Rivera, Francisco J ; Soto-Feliciano, Yadira M ; Pasqualucci, Laura ; Ciccia, Alberto ; Amengual, Jennifer E ; Lu, Chao

Nature communications, 2023-07, Vol.14 (1), p.4259-4259, Article 4259 [Periódico revisado por pares]

England: Nature Publishing Group

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10
PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes
PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes
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PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes

Soto-Feliciano, Yadira M ; Bartlebaugh, Jordan M E ; Liu, Yunpeng ; Sánchez-Rivera, Francisco J ; Bhutkar, Arjun ; Weintraub, Abraham S ; Buenrostro, Jason D ; Cheng, Christine S ; Regev, Aviv ; Jacks, Tyler E ; Young, Richard A ; Hemann, Michael T

Genes & development, 2017-05, Vol.31 (10), p.973-989 [Periódico revisado por pares]

United States: Cold Spring Harbor Laboratory Press

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