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Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure
Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure
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Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure

Asahina, Yoshikazu ; Wurtz, Nicholas R ; Arakawa, Kazuto ; Carson, Nancy ; Fujii, Kiyoshi ; Fukuchi, Kazunori ; Garcia, Ricardo ; Hsu, Mei-Yin ; Ishiyama, Junichi ; Ito, Bruce ; Kick, Ellen ; Lupisella, John ; Matsushima, Shingo ; Ohata, Kohei ; Ostrowski, Jacek ; Saito, Yoshifumi ; Tsuda, Kosuke ; Villarreal, Francisco ; Yamada, Hitomi ; Yamaoka, Toshikazu ; Wexler, Ruth ; Gordon, David ; Kohno, Yasushi

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9003-9019 [Periódico revisado por pares]

United States: American Chemical Society

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2
Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases
Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases
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Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases

Lauinger, Linda ; Li, Jing ; Shostak, Anton ; Cemel, Ibrahim Avi ; Ha, Nati ; Zhang, Yaru ; Merkl, Philipp E ; Obermeyer, Simon ; Stankovic-Valentin, Nicolas ; Schafmeier, Tobias ; Wever, Walter J ; Bowers, Albert A ; Carter, Kyle P ; Palmer, Amy E ; Tschochner, Herbert ; Melchior, Frauke ; Deshaies, Raymond J ; Brunner, Michael ; Diernfellner, Axel

Nature chemical biology, 2017-07, Vol.13 (7), p.709-714 [Periódico revisado por pares]

United States: Nature Publishing Group

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3
A single‐center, open‐label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers
A single‐center, open‐label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers
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A single‐center, open‐label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers

Finnema, Sjoerd J. ; Rossano, Samantha ; Naganawa, Mika ; Henry, Shannan ; Gao, Hong ; Pracitto, Richard ; Maguire, Ralph P. ; Mercier, Joël ; Kervyn, Sophie ; Nicolas, Jean‐Marie ; Klitgaard, Henrik ; DeBruyn, Steven ; Otoul, Christian ; Martin, Paul ; Muglia, Pierandrea ; Matuskey, David ; Nabulsi, Nabeel B. ; Huang, Yiyun ; Kaminski, Rafal M. ; Hannestad, Jonas ; Stockis, Armel ; Carson, Richard E.

Epilepsia (Copenhagen), 2019-05, Vol.60 (5), p.958-967 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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4
Pseurotin A Inhibits Osteoclastogenesis and Prevents Ovariectomized-Induced Bone Loss by Suppressing Reactive Oxygen Species
Pseurotin A Inhibits Osteoclastogenesis and Prevents Ovariectomized-Induced Bone Loss by Suppressing Reactive Oxygen Species
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Pseurotin A Inhibits Osteoclastogenesis and Prevents Ovariectomized-Induced Bone Loss by Suppressing Reactive Oxygen Species

Chen, Kai ; Qiu, Pengcheng ; Yuan, Yu ; Zheng, Lin ; He, Jianbo ; Wang, Chao ; Guo, Qiang ; Kenny, Jacob ; Liu, Qian ; Zhao, Jinmin ; Chen, Junhao ; Tickner, Jennifer ; Fan, Shunwu ; Lin, Xianfeng ; Xu, Jiake

Theranostics, 2019-01, Vol.9 (6), p.1634-1650 [Periódico revisado por pares]

Australia: Ivyspring International Publisher

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5
A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors
A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors
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A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors

Yang, Kai S. ; Ma, Xinyu R. ; Ma, Yuying ; Alugubelli, Yugendar R. ; Scott, Danielle A. ; Vatansever, Erol C. ; Drelich, Aleksandra K. ; Sankaran, Banumathi ; Geng, Zhi Z. ; Blankenship, Lauren R. ; Ward, Hannah E. ; Sheng, Yan J. ; Hsu, Jason C. ; Kratch, Kaci C. ; Zhao, Baoyu ; Hayatshahi, Hamed S. ; Liu, Jin ; Li, Pingwei ; Fierke, Carol A. ; Tseng, Chien‐Te K. ; Xu, Shiqing ; Liu, Wenshe Ray

ChemMedChem, 2021-03, Vol.16 (6), p.942-948 [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

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6
Brivaracetam: Rationale for discovery and preclinical profile of a selective SV2A ligand for epilepsy treatment
Brivaracetam: Rationale for discovery and preclinical profile of a selective SV2A ligand for epilepsy treatment
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Brivaracetam: Rationale for discovery and preclinical profile of a selective SV2A ligand for epilepsy treatment

Klitgaard, Henrik ; Matagne, Alain ; Nicolas, Jean‐Marie ; Gillard, Michel ; Lamberty, Yves ; De Ryck, Marc ; Kaminski, Rafal M. ; Leclercq, Karine ; Niespodziany, Isabelle ; Wolff, Christian ; Wood, Martyn ; Hannestad, Jonas ; Kervyn, Sophie ; Kenda, Benoit

Epilepsia (Copenhagen), 2016-04, Vol.57 (4), p.538-548 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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7
Biosynthesis of para-Cyclophane-Containing Hirsutellone Family of Fungal Natural Products
Biosynthesis of para-Cyclophane-Containing Hirsutellone Family of Fungal Natural Products
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Biosynthesis of para-Cyclophane-Containing Hirsutellone Family of Fungal Natural Products

Ohashi, Masao ; Kakule, Thomas B ; Tang, Man-Cheng ; Jamieson, Cooper S ; Liu, Mengting ; Zhao, Yi-Lei ; Houk, Kendall N ; Tang, Yi

Journal of the American Chemical Society, 2021-04, Vol.143 (15), p.5605-5609 [Periódico revisado por pares]

United States: American Chemical Society

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8
Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats
Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats
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Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

Onwordi, Ellis Chika ; Halff, Els F ; Whitehurst, Thomas ; Mansur, Ayla ; Cotel, Marie-Caroline ; Wells, Lisa ; Creeney, Hannah ; Bonsall, David ; Rogdaki, Maria ; Shatalina, Ekaterina ; Reis Marques, Tiago ; Rabiner, Eugenii A ; Gunn, Roger N ; Natesan, Sridhar ; Vernon, Anthony C ; Howes, Oliver D

Nature communications, 2020-01, Vol.11 (1), p.246-246, Article 246 [Periódico revisado por pares]

England: Nature Publishing Group

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9
Tetramic and tetronic acids: An update on new derivatives and biological aspects
Tetramic and tetronic acids: An update on new derivatives and biological aspects
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Tetramic and tetronic acids: An update on new derivatives and biological aspects

Schobert, Rainer ; Schlenk, Andrea

Bioorganic & medicinal chemistry, 2008-04, Vol.16 (8), p.4203-4221 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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10
Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV‑2 Main Protease in a Unique Binding Mode
Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV‑2 Main Protease in a Unique Binding Mode
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Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV‑2 Main Protease in a Unique Binding Mode

Lockbaum, Gordon J ; Henes, Mina ; Lee, Jeong Min ; Timm, Jennifer ; Nalivaika, Ellen A ; Thompson, Paul R ; Kurt Yilmaz, Nese ; Schiffer, Celia A

Biochemistry (Easton), 2021-10, Vol.60 (39), p.2925-2931 [Periódico revisado por pares]

United States: American Chemical Society

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