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1
Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial
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Artigo
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Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

Abe, Koji ; Aoki, Masashi ; Tsuji, Shoji ; Itoyama, Yasuto ; Sobue, Gen ; Togo, Masanori ; Hamada, Chikuma ; Tanaka, Masahiko ; Akimoto, Makoto ; Nakamura, Kazue ; Takahashi, Fumihiro ; Kondo, Kazuoki ; Yoshino, Hiide ; Sasaki, Hidenao ; Yabe, Ichiro ; Doi, Shizuki ; Warita, Hitoshi ; Imai, Takashi ; Ito, Hiroaki ; Fukuchi, Mitsumasa ; Osumi, Etsuko ; Wada, Manabu ; Nakano, Imaharu ; Morita, Mitsuya ; Ogata, Katsuhisa ; Maruki, Yuichi ; Ito, Kimiko ; Kano, Osamu ; Yamazaki, Mineo ; Takahashi, Yuji ; Ishiura, Hiroyuki ; Ogino, Mieko ; Koike, Ryoko ; Ishida, Chiho ; Uchiyama, Tsuyoshi ; Mizoguchi, Kouichi ; Obi, Tomokazu ; Watanabe, Hirohisa ; Atsuta, Naoki ; Aiba, Ikuko ; Taniguchi, Akira ; Sawada, Hideyuki ; Hazama, Takanori ; Fujimura, Harutoshi ; Kusaka, Hirofumi ; Kunieda, Takenobu ; Kikuchi, Hitoshi ; Matsuo, Hidenori ; Ueyama, Hidetsugu ; Uekawa, Kazutoshi ; Ueda, Masaki ; Murakami, Aiko ; Sumii, Rie ; Kudou, Takuya ; Morimoto, Kazunori ; Yoneoka, Takatomo ; Hirai, Manabu ; Sasaki, Kouichi ; Terai, Hidetomo ; Natori, Tomoko ; Matsui, Hiroshi ; Kotani, Kuniko ; Yoshida, Kaori ; Iwasaki, Tomohisa

Lancet neurology, 2017-07, Vol.16 (7), p.505-512 [Periódico revisado por pares]

England: Elsevier Ltd

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2
Retinal Diseases Associated with Oxidative Stress and the Effects of a Free Radical Scavenger (Edaravone)
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Artigo
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Retinal Diseases Associated with Oxidative Stress and the Effects of a Free Radical Scavenger (Edaravone)

Masuda, Tomomi ; Shimazawa, Masamitsu ; Hara, Hideaki Hrelia, Silvana

Oxidative medicine and cellular longevity, 2017-01, Vol.2017, p.9208489-14 [Periódico revisado por pares]

United States: Hindawi

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3
Antioxidant Therapy: Current Status and Future Prospects
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Artigo
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Antioxidant Therapy: Current Status and Future Prospects

Firuzi, O ; Miri, R ; Tavakkoli, M ; Saso, L

Current medicinal chemistry, 2011-09, Vol.18 (25), p.3871-3888 [Periódico revisado por pares]

United Arab Emirates: Bentham Science Publishers Ltd

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4
Edaravone alleviates Alzheimer’s disease-type pathologies and cognitive deficits
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Artigo
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Edaravone alleviates Alzheimer’s disease-type pathologies and cognitive deficits

Jiao, Shu-Sheng ; Yao, Xiu-Qing ; Liu, Yu-Hui ; Wang, Qing-Hua ; Zeng, Fan ; Lu, Jian-Jun ; Liu, Jia ; Zhu, Chi ; Shen, Lin-Lin ; Liu, Cheng-Hui ; Wang, Ye-Ran ; Zeng, Gui-Hua ; Parikh, Ankit ; Chen, Jia ; Liang, Chun-Rong ; Xiang, Yang ; Bu, Xian-Le ; Deng, Juan ; Li, Jing ; Xu, Juan ; Zeng, Yue-Qin ; Xu, Xiang ; Xu, Hai-Wei ; Zhong, Jin-Hua ; Zhou, Hua-Dong ; Zhou, Xin-Fu ; Wang, Yan-Jiang

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (16), p.5225-5230 [Periódico revisado por pares]

United States: National Academy of Sciences

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5
Molecules with versatile biological activities bearing antipyrinyl nucleus as pharmacophore
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Artigo
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Molecules with versatile biological activities bearing antipyrinyl nucleus as pharmacophore

Sahoo, Jyotirmaya ; Sahoo, Chita Ranjan ; Nandini Sarangi, Priyambada Kshiroda ; Prusty, Shakti Ketan ; Padhy, Rabindra Nath ; Paidesetty, Sudhir Kumar

European journal of medicinal chemistry, 2020-01, Vol.186, p.111911-111911, Article 111911 [Periódico revisado por pares]

France: Elsevier Masson SAS

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6
Edaravone efficacy in amyotrophic lateral sclerosis with reduced forced vital capacity: Post-hoc analysis of Study 19 (MCI186-19) [clinical trial NCT01492686]
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Artigo
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Edaravone efficacy in amyotrophic lateral sclerosis with reduced forced vital capacity: Post-hoc analysis of Study 19 (MCI186-19) [clinical trial NCT01492686]

Brooks, Benjamin Rix ; Heiman-Patterson, Terry ; Wiedau-Pazos, Martina ; Liu, Shawn ; Zhang, Jeffrey ; Apple, Stephen Zhang, Hong-Liang

PloS one, 2022-06, Vol.17 (6), p.e0258614-e0258614 [Periódico revisado por pares]

United States: Public Library of Science

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7
Edaravone alleviates cisplatin-induced neurobehavioral deficits via modulation of oxidative stress and inflammatory mediators in the rat hippocampus
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Artigo
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Edaravone alleviates cisplatin-induced neurobehavioral deficits via modulation of oxidative stress and inflammatory mediators in the rat hippocampus

Jangra, Ashok ; Kwatra, Mohit ; Singh, Tavleen ; Pant, Rajat ; Kushwah, Pawan ; Ahmed, Sahabuddin ; Dwivedi, Durgesh ; Saroha, Babita ; Lahkar, Mangala

European journal of pharmacology, 2016-11, Vol.791, p.51-61 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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8
Development of Edaravone Ionic Liquids and Their Application for the Treatment of Cerebral Ischemia/Reperfusion Injury
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Artigo
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Development of Edaravone Ionic Liquids and Their Application for the Treatment of Cerebral Ischemia/Reperfusion Injury

Fukuta, Tatsuya ; Ikeda-Imafuku, Mayumi ; Iwao, Yasunori

Molecular pharmaceutics, 2023-06, Vol.20 (6), p.3115-3126 [Periódico revisado por pares]

United States: American Chemical Society

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9
Edaravone and its clinical development for amyotrophic lateral sclerosis
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Artigo
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Edaravone and its clinical development for amyotrophic lateral sclerosis

Takei, Koji ; Watanabe, Kazutoshi ; Yuki, Satoshi ; Akimoto, Makoto ; Sakata, Takeshi ; Palumbo, Joseph

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2017-10, Vol.18 (sup1), p.5-10 [Periódico revisado por pares]

England: Taylor & Francis

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10
Oxidative Stress Interferes With White Matter Renewal After Prolonged Cerebral Hypoperfusion in Mice
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Artigo
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Oxidative Stress Interferes With White Matter Renewal After Prolonged Cerebral Hypoperfusion in Mice

Miyamoto, Nobukazu ; Maki, Takakuni ; Pham, Loc-Duyen D ; Hayakawa, Kazuhide ; Seo, Ji Hae ; Mandeville, Emiri T ; Mandeville, Joseph B ; Kim, Kyu-Won ; Lo, Eng H ; Arai, Ken

Stroke (1970), 2013-12, Vol.44 (12), p.3516-3521 [Periódico revisado por pares]

Hagerstown, MD: American Heart Association, Inc

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