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The role of AhR in transcriptional regulation of immune cell development and function
The role of AhR in transcriptional regulation of immune cell development and function
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The role of AhR in transcriptional regulation of immune cell development and function

Trikha, Prashant ; Lee, Dean A.

Biochimica et biophysica acta. Reviews on cancer, 2020-01, Vol.1873 (1), p.188335-188335, Article 188335 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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2
Inhibiting TGF-beta signaling preserves the function of highly activated, in vitro expanded natural killer cells in AML and colon cancer models
Inhibiting TGF-beta signaling preserves the function of highly activated, in vitro expanded natural killer cells in AML and colon cancer models
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Inhibiting TGF-beta signaling preserves the function of highly activated, in vitro expanded natural killer cells in AML and colon cancer models

Otegbeye, Folashade ; Ojo, Evelyn ; Moreton, Stephen ; Mackowski, Nathan ; Lee, Dean A ; de Lima, Marcos ; Wald, David N Gangopadhyay, Nupur

PloS one, 2018-01, Vol.13 (1), p.e0191358-e0191358 [Periódico revisado por pares]

United States: Public Library of Science

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3
Phase 1 clinical trial using mbIL21 ex vivo–expanded donor-derived NK cells after haploidentical transplantation
Phase 1 clinical trial using mbIL21 ex vivo–expanded donor-derived NK cells after haploidentical transplantation
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Phase 1 clinical trial using mbIL21 ex vivo–expanded donor-derived NK cells after haploidentical transplantation

Ciurea, Stefan O. ; Schafer, Jolie R. ; Bassett, Roland ; Denman, Cecele J. ; Cao, Kai ; Willis, Dana ; Rondon, Gabriela ; Chen, Julianne ; Soebbing, Doris ; Kaur, Indreshpal ; Gulbis, Alison ; Ahmed, Sairah ; Rezvani, Katayoun ; Shpall, Elizabeth J. ; Lee, Dean A. ; Champlin, Richard E.

Blood, 2017-10, Vol.130 (16), p.1857-1868 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity
Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity
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Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity

Caruso, Hillary G ; Hurton, Lenka V ; Najjar, Amer ; Rushworth, David ; Ang, Sonny ; Olivares, Simon ; Mi, Tiejuan ; Switzer, Kirsten ; Singh, Harjeet ; Huls, Helen ; Lee, Dean A ; Heimberger, Amy B ; Champlin, Richard E ; Cooper, Laurence J N

Cancer research (Chicago, Ill.), 2015-09, Vol.75 (17), p.3505-3518 [Periódico revisado por pares]

United States

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5
Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells
Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells
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Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells

Denman, Cecele J ; Senyukov, Vladimir V ; Somanchi, Srinivas S ; Phatarpekar, Prasad V ; Kopp, Lisa M ; Johnson, Jennifer L ; Singh, Harjeet ; Hurton, Lenka ; Maiti, Sourindra N ; Huls, M Helen ; Champlin, Richard E ; Cooper, Laurence J N ; Lee, Dean A Dieli, Francesco

PloS one, 2012-01, Vol.7 (1), p.e30264-e30264 [Periódico revisado por pares]

United States: Public Library of Science

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6
Repression of GSK3 restores NK cell cytotoxicity in AML patients
Repression of GSK3 restores NK cell cytotoxicity in AML patients
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Repression of GSK3 restores NK cell cytotoxicity in AML patients

Parameswaran, Reshmi ; Ramakrishnan, Parameswaran ; Moreton, Stephen A ; Xia, Zhiqiang ; Hou, Yongchun ; Lee, Dean A ; Gupta, Kalpana ; deLima, Marcos ; Beck, Rose C ; Wald, David N

Nature communications, 2016-04, Vol.7 (1), p.11154-11154, Article 11154 [Periódico revisado por pares]

England: Nature Publishing Group

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7
Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target
Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target
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Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target

Dufva, Olli ; Kankainen, Matti ; Kelkka, Tiina ; Sekiguchi, Nodoka ; Awad, Shady Adnan ; Eldfors, Samuli ; Yadav, Bhagwan ; Kuusanmäki, Heikki ; Malani, Disha ; Andersson, Emma I ; Pietarinen, Paavo ; Saikko, Leena ; Kovanen, Panu E ; Ojala, Teija ; Lee, Dean A ; Loughran, Jr, Thomas P ; Nakazawa, Hideyuki ; Suzumiya, Junji ; Suzuki, Ritsuro ; Ko, Young Hyeh ; Kim, Won Seog ; Chuang, Shih-Sung ; Aittokallio, Tero ; Chan, Wing C ; Ohshima, Koichi ; Ishida, Fumihiro ; Mustjoki, Satu

Nature communications, 2018-04, Vol.9 (1), p.1567-12, Article 1567 [Periódico revisado por pares]

England: Nature Publishing Group

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8
Natural killer cell therapy for hematologic malignancies: successes, challenges, and the future
Natural killer cell therapy for hematologic malignancies: successes, challenges, and the future
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Natural killer cell therapy for hematologic malignancies: successes, challenges, and the future

Lamb, Margaret G ; Rangarajan, Hemalatha G ; Tullius, Brian P ; Lee, Dean A

Stem cell research & therapy, 2021-03, Vol.12 (1), p.211-211, Article 211 [Periódico revisado por pares]

England: BioMed Central Ltd

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9
Efficient and Robust NK-Cell Transduction With Baboon Envelope Pseudotyped Lentivector
Efficient and Robust NK-Cell Transduction With Baboon Envelope Pseudotyped Lentivector
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Efficient and Robust NK-Cell Transduction With Baboon Envelope Pseudotyped Lentivector

Colamartino, Aurelien B L ; Lemieux, William ; Bifsha, Panojot ; Nicoletti, Simon ; Chakravarti, Nitin ; Sanz, Joaquín ; Roméro, Hugo ; Selleri, Silvia ; Béland, Kathie ; Guiot, Mélanie ; Tremblay-Laganière, Camille ; Dicaire, Renée ; Barreiro, Luis ; Lee, Dean A ; Verhoeyen, Els ; Haddad, Elie

Frontiers in immunology, 2019-12, Vol.10, p.2873-2873 [Periódico revisado por pares]

Switzerland: Frontiers Research Foundation

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10
Toward eliminating HLA class I expression to generate universal cells from allogeneic donors
Toward eliminating HLA class I expression to generate universal cells from allogeneic donors
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Toward eliminating HLA class I expression to generate universal cells from allogeneic donors

Torikai, Hiroki ; Reik, Andreas ; Soldner, Frank ; Warren, Edus H. ; Yuen, Carrie ; Zhou, Yuanyue ; Crossland, Denise L. ; Huls, Helen ; Littman, Nicholas ; Zhang, Ziying ; Tykodi, Scott S. ; Kebriaei, Partow ; Lee, Dean A. ; Miller, Jeffrey C. ; Rebar, Edward J. ; Holmes, Michael C. ; Jaenisch, Rudolf ; Champlin, Richard E. ; Gregory, Philip D. ; Cooper, Laurence J.N.

Blood, 2013-08, Vol.122 (8), p.1341-1349 [Periódico revisado por pares]

United States: Elsevier Inc

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