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Systemic Therapy for Melanoma: ASCO Guideline
Systemic Therapy for Melanoma: ASCO Guideline
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Systemic Therapy for Melanoma: ASCO Guideline

Seth, Rahul ; Messersmith, Hans ; Kaur, Varinder ; Kirkwood, John M ; Kudchadkar, Ragini ; McQuade, Jennifer Leigh ; Provenzano, Anthony ; Swami, Umang ; Weber, Jeffrey ; Alluri, Krishna C ; Agarwala, Sanjiv ; Ascierto, Paolo A ; Atkins, Michael B ; Davis, Nancy ; Ernstoff, Marc S ; Faries, Mark B ; Gold, Jason S ; Guild, Samantha ; Gyorki, David E ; Khushalani, Nikhil I ; Meyers, Michael O ; Robert, Caroline ; Santinami, Mario ; Sehdev, Amikar ; Sondak, Vernon K ; Spurrier, Gilliosa ; Tsai, Katy K ; van Akkooi, Alexander ; Funchain, Pauline

Journal of clinical oncology, 2020-11, Vol.38 (33), p.3947-3970 [Periódico revisado por pares]

United States

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2
Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma
Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma
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Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma

Robert, Caroline ; Grob, Jean J ; Stroyakovskiy, Daniil ; Karaszewska, Boguslawa ; Hauschild, Axel ; Levchenko, Evgeny ; Chiarion Sileni, Vanna ; Schachter, Jacob ; Garbe, Claus ; Bondarenko, Igor ; Gogas, Helen ; Mandalá, Mario ; Haanen, John B.A.G ; Lebbé, Celeste ; Mackiewicz, Andrzej ; Rutkowski, Piotr ; Nathan, Paul D ; Ribas, Antoni ; Davies, Michael A ; Flaherty, Keith T ; Burgess, Paul ; Tan, Monique ; Gasal, Eduard ; Voi, Maurizio ; Schadendorf, Dirk ; Long, Georgina V

The New England journal of medicine, 2019-08, Vol.381 (7), p.626-636 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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3
Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study
Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study
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Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study

Long, G.V. ; Flaherty, K.T. ; Stroyakovskiy, D. ; Gogas, H. ; Levchenko, E. ; de Braud, F. ; Larkin, J. ; Garbe, C. ; Jouary, T. ; Hauschild, A. ; Chiarion-Sileni, V. ; Lebbe, C. ; Mandalà, M. ; Millward, M. ; Arance, A. ; Bondarenko, I. ; Haanen, J.B.A.G. ; Hansson, J. ; Utikal, J. ; Ferraresi, V. ; Mohr, P. ; Probachai, V. ; Schadendorf, D. ; Nathan, P. ; Robert, C. ; Ribas, A. ; Davies, M.A. ; Lane, S.R. ; Legos, J.J. ; Mookerjee, B. ; Grob, J.-J.

Annals of oncology, 2017-07, Vol.28 (7), p.1631-1639 [Periódico revisado por pares]

England: Elsevier Ltd

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4
Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600-Mutant Anaplastic Thyroid Cancer
Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600-Mutant Anaplastic Thyroid Cancer
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Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600-Mutant Anaplastic Thyroid Cancer

Subbiah, Vivek ; Kreitman, Robert J ; Wainberg, Zev A ; Cho, Jae Yong ; Schellens, Jan H M ; Soria, Jean Charles ; Wen, Patrick Y ; Zielinski, Christoph ; Cabanillas, Maria E ; Urbanowitz, Gladys ; Mookerjee, Bijoyesh ; Wang, Dazhe ; Rangwala, Fatima ; Keam, Bhumsuk

Journal of clinical oncology, 2018-01, Vol.36 (1), p.7-13 [Periódico revisado por pares]

United States: American Society of Clinical Oncology

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5
Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib
Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib
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Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib

Robert, Caroline ; Karaszewska, Boguslawa ; Schachter, Jacob ; Rutkowski, Piotr ; Mackiewicz, Andrzej ; Stroiakovski, Daniil ; Lichinitser, Michael ; Dummer, Reinhard ; Grange, Florent ; Mortier, Laurent ; Chiarion-Sileni, Vanna ; Drucis, Kamil ; Krajsova, Ivana ; Hauschild, Axel ; Lorigan, Paul ; Wolter, Pascal ; Long, Georgina V ; Flaherty, Keith ; Nathan, Paul ; Ribas, Antoni ; Martin, Anne-Marie ; Sun, Peng ; Crist, Wendy ; Legos, Jeff ; Rubin, Stephen D ; Little, Shonda M ; Schadendorf, Dirk

The New England journal of medicine, 2015-01, Vol.372 (1), p.30-39 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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6
Highly Emissive Dye-Sensitized Upconversion Nanostructure for Dual-Photosensitizer Photodynamic Therapy and Bioimaging
Highly Emissive Dye-Sensitized Upconversion Nanostructure for Dual-Photosensitizer Photodynamic Therapy and Bioimaging
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Highly Emissive Dye-Sensitized Upconversion Nanostructure for Dual-Photosensitizer Photodynamic Therapy and Bioimaging

Xu, Jiating ; Yang, Piaoping ; Sun, Mingdi ; Bi, Huiting ; Liu, Bin ; Yang, Dan ; Gai, Shili ; He, Fei ; Lin, Jun

ACS nano, 2017-04, Vol.11 (4), p.4133-4144 [Periódico revisado por pares]

United States: American Chemical Society

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7
Long-Term Outcomes in Patients With BRAF V600-Mutant Metastatic Melanoma Who Received Dabrafenib Combined With Trametinib
Long-Term Outcomes in Patients With BRAF V600-Mutant Metastatic Melanoma Who Received Dabrafenib Combined With Trametinib
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Long-Term Outcomes in Patients With BRAF V600-Mutant Metastatic Melanoma Who Received Dabrafenib Combined With Trametinib

Long, Georgina V ; Eroglu, Zeynep ; Infante, Jeffrey ; Patel, Sapna ; Daud, Adil ; Johnson, Douglas B ; Gonzalez, Rene ; Kefford, Richard ; Hamid, Omid ; Schuchter, Lynn ; Cebon, Jonathan ; Sharfman, William ; McWilliams, Robert ; Sznol, Mario ; Redhu, Suman ; Gasal, Eduard ; Mookerjee, Bijoyesh ; Weber, Jeffrey ; Flaherty, Keith T

Journal of clinical oncology, 2018-03, Vol.36 (7), p.667-673 [Periódico revisado por pares]

United States: American Society of Clinical Oncology

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8
Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial
Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial
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Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial

Long, Georgina V, MD ; Stroyakovskiy, Daniil, MD ; Gogas, Helen, MD ; Levchenko, Evgeny, MD ; de Braud, Filippo, MD ; Larkin, James, FRCP ; Garbe, Claus, Prof ; Jouary, Thomas, MD ; Hauschild, Axel, Prof ; Grob, Jean-Jacques, Prof ; Chiarion-Sileni, Vanna, MD ; Lebbe, Celeste, Prof ; Mandalà, Mario, MD ; Millward, Michael, Prof ; Arance, Ana, MD ; Bondarenko, Igor, Prof ; Haanen, John B A G, Prof ; Hansson, Johan, Prof ; Utikal, Jochen, Prof ; Ferraresi, Virginia, MD ; Kovalenko, Nadezhda, Prof ; Mohr, Peter, MD ; Probachai, Volodymr, MD ; Schadendorf, Dirk, Prof ; Nathan, Paul, MD ; Robert, Caroline, MD ; Ribas, Antoni, Prof ; DeMarini, Douglas J, PhD ; Irani, Jhangir G, MA ; Swann, Suzanne, PhD ; Legos, Jeffrey J, PhD ; Jin, Fan, MD ; Mookerjee, Bijoyesh, MD ; Flaherty, Keith, MD

The Lancet (British edition), 2015-08, Vol.386 (9992), p.444-451 [Periódico revisado por pares]

England: Elsevier Ltd

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9
Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma
Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma
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Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma

Long, Georgina V ; Stroyakovskiy, Daniil ; Gogas, Helen ; Levchenko, Evgeny ; de Braud, Filippo ; Larkin, James ; Garbe, Claus ; Jouary, Thomas ; Hauschild, Axel ; Grob, Jean Jacques ; Chiarion Sileni, Vanna ; Lebbe, Celeste ; Mandalà, Mario ; Millward, Michael ; Arance, Ana ; Bondarenko, Igor ; Haanen, John B.A.G ; Hansson, Johan ; Utikal, Jochen ; Ferraresi, Virginia ; Kovalenko, Nadezhda ; Mohr, Peter ; Probachai, Volodymyr ; Schadendorf, Dirk ; Nathan, Paul ; Robert, Caroline ; Ribas, Antoni ; DeMarini, Douglas J ; Irani, Jhangir G ; Casey, Michelle ; Ouellet, Daniele ; Martin, Anne-Marie ; Le, Ngocdiep ; Patel, Kiran ; Flaherty, Keith

The New England journal of medicine, 2014-11, Vol.371 (20), p.1877-1888 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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10
A phase Ib dose-escalation study of the oral pan-PI3K inhibitor buparlisib (BKM120) in combination with the oral MEK1/2 inhibitor trametinib (GSK1120212) in patients with selected advanced solid tumors
A phase Ib dose-escalation study of the oral pan-PI3K inhibitor buparlisib (BKM120) in combination with the oral MEK1/2 inhibitor trametinib (GSK1120212) in patients with selected advanced solid tumors
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A phase Ib dose-escalation study of the oral pan-PI3K inhibitor buparlisib (BKM120) in combination with the oral MEK1/2 inhibitor trametinib (GSK1120212) in patients with selected advanced solid tumors

Bedard, Philippe L ; Tabernero, Josep ; Janku, Filip ; Wainberg, Zev A ; Paz-Ares, Luis ; Vansteenkiste, Johan ; Van Cutsem, Eric ; Pérez-García, José ; Stathis, Anastasios ; Britten, Carolyn D ; Le, Ngocdiep ; Carter, Kirsten ; Demanse, David ; Csonka, Denes ; Peters, Malte ; Zubel, Angela ; Nauwelaerts, Heidi ; Sessa, Cristiana

Clinical cancer research, 2015-02, Vol.21 (4), p.730-738 [Periódico revisado por pares]

United States

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