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Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects
Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects
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Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects

STONE, Nimalie D ; DUNAWAY, Shelia B ; PARK, Jeong-Gun ; LALAMA, Christina ; SNYDER, Sally ; KALLUNGAL, Beatrice ; KLINGMAN, Karin L ; HENDRIX, Craig W ; FLEXNER, Charles ; TIERNEY, Camlin ; CALANDRA, Gary B ; BECKER, Stephen ; CAO, Ying-Jun ; WIGGINS, Ilene P ; CONLEY, Jeanne ; MACFARLAND, Ron T

Antimicrobial Agents and Chemotherapy, 2007-07, Vol.51 (7), p.2351-2358 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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2
Pharmacology of AMD3465: A small molecule antagonist of the chemokine receptor CXCR4
Pharmacology of AMD3465: A small molecule antagonist of the chemokine receptor CXCR4
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Pharmacology of AMD3465: A small molecule antagonist of the chemokine receptor CXCR4

Bodart, Veronique ; Anastassov, Virginia ; Darkes, Marilyn C. ; Idzan, Stefan R. ; Labrecque, Jean ; Lau, Gloria ; Mosi, Renee M. ; Neff, Kathleen S. ; Nelson, Kim L. ; Ruzek, Melanie C. ; Patel, Ketan ; Santucci, Zefferino ; Scarborough, Robert ; Wong, Rebecca S.Y. ; Bridger, Gary J. ; MacFarland, Ron T. ; Fricker, Simon P.

Biochemical pharmacology, 2009-10, Vol.78 (8), p.993-1000 [Periódico revisado por pares]

Amsterdam: Elsevier Inc

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3
Pharmacokinetic Effect of AMD070, an Oral CXCR4 Antagonist, on CYP3A4 and CYP2D6 Substrates Midazolam and Dextromethorphan in Healthy Volunteers
Pharmacokinetic Effect of AMD070, an Oral CXCR4 Antagonist, on CYP3A4 and CYP2D6 Substrates Midazolam and Dextromethorphan in Healthy Volunteers
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Pharmacokinetic Effect of AMD070, an Oral CXCR4 Antagonist, on CYP3A4 and CYP2D6 Substrates Midazolam and Dextromethorphan in Healthy Volunteers

Nyunt, Myaing M ; Becker, Stephen ; MacFarland, Ron T ; Chee, Priscilla ; Scarborough, Robert ; Everts, Stephanie ; Calandra, Gary B ; Hendrix, Craig W

Journal of acquired immune deficiency syndromes (1999), 2008-04, Vol.47 (5), p.559-565 [Periódico revisado por pares]

Hagerstown, MD: Lippincott Williams & Wilkins, Inc

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4
Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects
Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects
Material Type:
Artigo 		Adicionar ao Meu Espaço

Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects

Stone, Nimalie D ; Dunaway, Shelia B ; Flexner, Charles ; Tierney, Camlin ; Calandra, Gary B ; Becker, Stephen ; Cao, Ying-Jun ; Wiggins, Ilene P ; Conley, Jeanne ; MacFarland, Ron T ; Park, Jeong-Gun ; Lalama, Christina ; Snyder, Sally ; Kallungal, Beatrice ; Klingman, Karin L ; Hendrix, Craig W

Antimicrobial agents and chemotherapy, 2007-08, Vol.51 (8), p.3047-3047 [Periódico revisado por pares]

American Society for Microbiology

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5
A Mobilizing Regimen of AMD3100 and G-CSF Increases Stem Cell Collection in Patients with Hodgkin's Disease, and PK Is Similar to That of Non-Cancer Patients
A Mobilizing Regimen of AMD3100 and G-CSF Increases Stem Cell Collection in Patients with Hodgkin's Disease, and PK Is Similar to That of Non-Cancer Patients
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A Mobilizing Regimen of AMD3100 and G-CSF Increases Stem Cell Collection in Patients with Hodgkin's Disease, and PK Is Similar to That of Non-Cancer Patients

Cashen, Amanda F. ; Calandra, Gary ; MacFarland, Ron ; Lopez, Sandra ; DiPersio, John F.

Blood, 2006-11, Vol.108 (11), p.3053-3053 [Periódico revisado por pares]

Elsevier Inc

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6
Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model. Commentary
Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model. Commentary
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Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model. Commentary

DEVINE, Steven M ; BURROUGHS, Lauri ; MIELCAREK, Marco ; LITTLE, Marie-Térèse ; BRIDGER, Gary ; MACFARLAND, Ron ; FRICKER, Simon ; LABRECQUE, Jean ; SANDMAIER, Brenda M ; STORB, Rainer

Blood, 2005, Vol.106 (12), p.4002-3686 [Periódico revisado por pares]

Washington, DC: The Americain Society of Hematology

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7
Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model
Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model
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Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model

Burroughs, Lauri ; Mielcarek, Marco ; Little, Marie-Térèse ; Bridger, Gary ; MacFarland, Ron ; Fricker, Simon ; Labrecque, Jean ; Sandmaier, Brenda M. ; Storb, Rainer

Blood, 2005-12, Vol.106 (12), p.4002-4008 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Proof of Activity with AMD11070, an Orally Bioavailable Inhibitor of CXCR4-Tropic HIV Type 1
Proof of Activity with AMD11070, an Orally Bioavailable Inhibitor of CXCR4-Tropic HIV Type 1
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Proof of Activity with AMD11070, an Orally Bioavailable Inhibitor of CXCR4-Tropic HIV Type 1

Moyle, Graeme ; DeJesus, Edwin ; Boffito, Marta ; Wong, Rebecca S. ; Gibney, Colleen ; Badel, Karin ; MacFarland, Ron ; Calandra, Gary ; Bridger, Gary ; Becker, Stephen

Clinical infectious diseases, 2009-03, Vol.48 (6), p.798-805 [Periódico revisado por pares]

Oxford: The University of Chicago Press

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9
Effect of Low-Dose Ritonavir on the Pharmacokinetics of the CXCR4 Antagonist AMD070 in Healthy Volunteers
Effect of Low-Dose Ritonavir on the Pharmacokinetics of the CXCR4 Antagonist AMD070 in Healthy Volunteers
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Effect of Low-Dose Ritonavir on the Pharmacokinetics of the CXCR4 Antagonist AMD070 in Healthy Volunteers

YING JUN CAO ; FLEXNER, Charles W ; BECKER, Stephen ; HENDRIX, Craig W ; DUNAWAY, Shelia ; PARK, Jeong-Gun ; KLINGMAN, Karin ; WIGGINS, Ilene ; CONLEY, Jeanne ; RADEBAUGH, Christine ; KASHUBA, Angela D ; MACFARLAND, Ron

Antimicrobial Agents and Chemotherapy, 2008-05, Vol.52 (5), p.1630-1634 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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10
Design of Substituted Imidazolidinylpiperidinylbenzoic Acids as Chemokine Receptor 5 Antagonists: Potent Inhibitors of R5 HIV‑1 Replication
Design of Substituted Imidazolidinylpiperidinylbenzoic Acids as Chemokine Receptor 5 Antagonists: Potent Inhibitors of R5 HIV‑1 Replication
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Design of Substituted Imidazolidinylpiperidinylbenzoic Acids as Chemokine Receptor 5 Antagonists: Potent Inhibitors of R5 HIV‑1 Replication

Skerlj, Renato ; Bridger, Gary ; Zhou, Yuanxi ; Bourque, Elyse ; McEachern, Ernest ; Metz, Markus ; Harwig, Curtis ; Li, Tong-Shuang ; Yang, Wen ; Bogucki, David ; Zhu, Yongbao ; Langille, Jonathan ; Veale, Duane ; Ba, Tuya ; Bey, Michael ; Baird, Ian ; Kaller, Alan ; Krumpak, Maria ; Leitch, David ; Satori, Michael ; Vocadlo, Krystyna ; Guay, Danielle ; Nan, Susan ; Yee, Helen ; Crawford, Jason ; Chen, Gang ; Wilson, Trevor ; Carpenter, Bryon ; Gauthier, David ; MacFarland, Ron ; Mosi, Renee ; Bodart, Veronique ; Wong, Rebecca ; Fricker, Simon ; Schols, Dominique

Journal of medicinal chemistry, 2013-10, Vol.56 (20), p.8049-8065 [Periódico revisado por pares]

United States: American Chemical Society

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