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Material Type: Artigo
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Exploring Novel Variants of the Cytochrome P450 Reductase Gene ( POR ) from the Genome Aggregation Database by Integrating Bioinformatic Tools and Functional AssaysRojas Velazquez, Maria Natalia ; Therkelsen, Søren ; Pandey, Amit VBiomolecules (Basel, Switzerland), 2023-11, Vol.13 (12), p.1728 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Hepatic nuclear factor 4 alpha promotes the ferroptosis of lung adenocarcinoma via transcriptional activation of cytochrome P450 oxidoreductaseBesskaya, Valeria ; Zhang, Huan ; Bian, Yunyi ; Liang, Jiaqi ; Bi, Guoshu ; Shan, Guangyao ; Zhan, Cheng ; Lin, ZongwuPeerJ (San Francisco, CA), 2023-05, Vol.11, p.e15377-e15377, Article e15377 [Periódico revisado por pares]United States: PeerJ. LtdTexto completo disponível |
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Cardiac Disease Alters Myocardial Tissue Levels of Epoxyeicosatrienoic Acids and Key Proteins Involved in Their Biosynthesis and DegradationAliwarga, Theresa ; Dinh, Jean C. ; Heyward, Scott ; Prasad, Bhagwat ; Gharib, Sina A. ; Lemaitre, Rozenn N. ; Sotoodehnia, Nona ; Totah, Rheem A.International journal of molecular sciences, 2022-10, Vol.23 (20), p.12433 [Periódico revisado por pares]Basel: MDPI AGTexto completo disponível |
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Loss of Protein Stability and Function Caused by P228L Variation in NADPH-Cytochrome P450 Reductase Linked to Lower Testosterone LevelsRojas Velazquez, Maria Natalia ; Noebauer, Mathias ; Pandey, Amit VInternational journal of molecular sciences, 2022-09, Vol.23 (17), p.10141 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Material Type: Artigo
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Characterization ofPharmacogenomics, 2022-08 [Periódico revisado por pares]Future Medicine LtdTexto completo disponível |
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Material Type: Artigo
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A disease‐associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transferSmeets, Elien ; Huang, Shengyun ; Lee, Xiao Yin ; Van Nieuwenhove, Erika ; Helsen, Christine ; Handle, Florian ; Moris, Lisa ; El Kharraz, Sarah ; Eerlings, Roy ; Devlies, Wout ; Willemsen, Mathijs ; Bücken, Leoni ; Prezzemolo, Teresa ; Humblet‐Baron, Stephanie ; Voet, Arnout ; Rochtus, Anne ; Van Schepdael, Ann ; Zegher, Francis ; Claessens, FrankJournal of cachexia, sarcopenia and muscle, 2022-08, Vol.13 (4), p.2242-2253 [Periódico revisado por pares]Germany: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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Generation of Caco-2 cells stably expressing CYP3A4·POR·UGT1A1 and CYP3A4·POR·UGT1A16 using a PITCh systemNegoro, Ryosuke ; Yamada, Naoki ; Watanabe, Keita ; Kono, Yusuke ; Fujita, TakuyaArchives of toxicology, 2022-02, Vol.96 (2), p.499-510 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Material Type: Artigo
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POR polymorphisms are associated with 21 hydroxylase deficiencyPecori Giraldi, F. ; Einaudi, S. ; Sesta, A. ; Verna, F. ; Messina, M. ; Manieri, C. ; Menegatti, E. ; Ghizzoni, L.Journal of endocrinological investigation, 2021-10, Vol.44 (10), p.2219-2226 [Periódico revisado por pares]Cham: Springer International PublishingTexto completo disponível |
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Material Type: Artigo
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19-hydroxy Steroids in the Aromatase Reaction: Review on Expression and Potential FunctionsAbaffy, Tatjana ; Matsunami, HiroakiJournal of the Endocrine Society, 2021-07, Vol.5 (7) [Periódico revisado por pares]US: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Vascular biotransformation of organic nitrates is independent of cytochrome P450 monooxygenasesLopez, Melina ; Malacarne, Pedro F. ; Gajos‐Draus, Anna ; Ding, Xinxin ; Daiber, Andreas ; Lundberg, Jon O. ; Offermanns, Stefan ; Brandes, Ralf P. ; Rezende, FláviaBritish journal of pharmacology, 2021-04, Vol.178 (7), p.1495-1506 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |