Type 2 diabetes-associated variants of the MT 2 melatonin receptor affect distinct modes of signaling

Karamitri, Angeliki ; Plouffe, Bianca ; Bonnefond, Amélie ; Chen, Min ; Gallion, Jonathan ; Guillaume, Jean-Luc ; Hegron, Alan ; Boissel, Mathilde ; Canouil, Mickaël ; Langenberg, Claudia ; Wareham, Nicholas J ; Le Gouill, Christian ; Lukasheva, Viktoria ; Lichtarge, Olivier ; Froguel, Philippe ; Bouvier, Michel ; Jockers, Ralf

United States: American Association for the Advancement of Science (AAAS)

Full text available

Type 2 diabetes–associated variants of the MT2 melatonin receptor affect distinct modes of signaling

Karamitri Angeliki ; Plouffe Bianca ; Bonnefond Amélie ; Chen, Min ; Gallion, Jonathan ; Guillaume Jean-Luc ; Hegron Alan ; Boissel Mathilde ; Canouil Mickaël ; Langenberg, Claudia ; Wareham, Nicholas J ; Le Gouill Christian ; Lukasheva Viktoria ; Lichtarge Olivier ; Froguel Philippe ; Bouvier, Michel ; Jockers Ralf

Washington: The American Association for the Advancement of Science

Full text available

Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9

Luttrell, Louis M ; Wang, Jialu ; Plouffe, Bianca ; Smith, Jeffrey S ; Yamani, Lama ; Kaur, Suneet ; Jean-Charles, Pierre-Yves ; Gauthier, Christophe ; Lee, Mi-Hye ; Pani, Biswaranjan ; Kim, Jihee ; Ahn, Seungkirl ; Rajagopal, Sudarshan ; Reiter, Eric ; Bouvier, Michel ; Shenoy, Sudha K ; Laporte, Stéphane A ; Rockman, Howard A ; Lefkowitz, Robert J

United States: The American Association for the Advancement of Science

Full text available

Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors

Yoon Namkung Christian LeGouill; Sahil Kumar; Yubo Cao; Larissa B Teixeira; Viktoriya Lukasheva; Jenna Giubilaro; Sarah Capelupe Simões; Jean-Michel Longpré; Dominic Devost; Terence E Hébert; Graciela Piñeyro; Richard Leduc; Claudio Miguel da Costa Neto; Michel Bouvier; Stéphane A Laporte

Washington 2018

Online access. The library also has physical copies.

Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors

Namkung, Yoon ; LeGouill, Christian ; Kumar, Sahil ; Cao, Yubo ; Teixeira, Larissa B ; Lukasheva, Viktoriya ; Giubilaro, Jenna ; Simões, Sarah C ; Longpré, Jean-Michel ; Devost, Dominic ; Hébert, Terence E ; Piñeyro, Graciela ; Leduc, Richard ; Costa-Neto, Claudio M ; Bouvier, Michel ; Laporte, Stéphane A

United States: The American Association for the Advancement of Science

Full text available

Conformation- and activation-based BRET sensors differentially report on GPCR–G protein coupling

Wright, Shane C. ; Avet, Charlotte ; Gaitonde, Supriya A. ; Muneta-Arrate, Itziar ; Le Gouill, Christian ; Hogue, Mireille ; Breton, Billy ; Koutsilieri, Stefania ; Alarcia, Rebeca Diez ; Héroux, Madeleine ; Lauschke, Volker M. ; Bouvier, Michel

Washington: The American Association for the Advancement of Science

Full text available

FZD(5) is a G alpha(q)-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs

Wright, Shane C. ; Canizal, Maria Consuelo Alonso ; Benkel, Tobias ; Simon, Katharina ; Le Gouill, Christian ; Matricon, Pierre ; Namkung, Yoon ; Lukasheva, Viktoria ; Koenig, Gabriele M. ; Laporte, Stephane A. ; Carlsson, Jens ; Kostenis, Evi ; Bouvier, Michel ; Schulte, Gunnar ; Hoffmann, Carsten

Full text available

FZD 5 is a Gα q -coupled receptor that exhibits the functional hallmarks of prototypical GPCRs

Wright, Shane C ; Cañizal, Maria Consuelo Alonso ; Benkel, Tobias ; Simon, Katharina ; Le Gouill, Christian ; Matricon, Pierre ; Namkung, Yoon ; Lukasheva, Viktoria ; König, Gabriele M ; Laporte, Stéphane A ; Carlsson, Jens ; Kostenis, Evi ; Bouvier, Michel ; Schulte, Gunnar ; Hoffmann, Carsten

United States

Full text available

FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs

Wright, Shane C ; Cañizal Maria Consuelo Alonso ; Benkel Tobias ; Simon, Katharina ; Le Gouill Christian ; Matricon Pierre ; Yoon, Namkung ; Lukasheva Viktoria ; König, Gabriele M ; Laporte, Stéphane A ; Carlsson Jens ; Kostenis Evi ; Bouvier, Michel ; Schulte, Gunnar ; Hoffmann, Carsten

Washington: The American Association for the Advancement of Science

Full text available

A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells

Yagi, Hiroshi ; Tan, Wenfu ; Dillenburg-Pilla, Patricia ; Armando, Sylvain ; Amornphimoltham, Panomwat ; Simaan, May ; Weigert, Roberto ; Molinolo, Alfredo A ; Bouvier, Michel ; Gutkind, J Silvio

United States

Full text available