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1-[1-(2-Benzo[b]thiopheneyl)cyclohexyl]piperidine Hydrochloride (BTCP) Yields Two Active Primary Metabolites in Vitro:  Synthesis, Identification from Rat Liver Microsome Extracts, and Affinity for the Neuronal Dopamine Transporter
1-[1-(2-Benzo[b]thiopheneyl)cyclohexyl]piperidine Hydrochloride (BTCP) Yields Two Active Primary Metabolites in Vitro:  Synthesis, Identification from Rat Liver Microsome Extracts, and Affinity for the Neuronal Dopamine Transporter
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1-[1-(2-Benzo[b]thiopheneyl)cyclohexyl]piperidine Hydrochloride (BTCP) Yields Two Active Primary Metabolites in Vitro:  Synthesis, Identification from Rat Liver Microsome Extracts, and Affinity for the Neuronal Dopamine Transporter

Deleuze-Masquefa, Carine ; Michaud, Martine ; Vignon, Jacques ; Kamenka, Jean-Marc

Journal of medicinal chemistry, 1997-12, Vol.40 (25), p.4019-4025 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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2
1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia
1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia
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1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia

Anandan, Sampath-Kumar ; Webb, Heather Kay ; Chen, Dawn ; Wang, Yi-Xin (Jim) ; Aavula, Basker R. ; Cases, Sylvaine ; Cheng, Ying ; Do, Zung N. ; Mehra, Upasana ; Tran, Vinh ; Vincelette, Jon ; Waszczuk, Joanna ; White, Kathy ; Wong, Kenneth R. ; Zhang, Le-Ning ; Jones, Paul D. ; Hammock, Bruce D. ; Patel, Dinesh V. ; Whitcomb, Randall ; MacIntyre, D. Euan ; Sabry, James ; Gless, Richard

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (3), p.983-988 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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3
1-[1-Hexyl-6-(methyloxy)-1H-indazol-3-yl]-2-methyl-1-propanone, a Potent and Highly Selective Small Molecule Blocker of the Large-Conductance Voltage-Gated and Calcium-Dependent K+ Channel
1-[1-Hexyl-6-(methyloxy)-1H-indazol-3-yl]-2-methyl-1-propanone, a Potent and Highly Selective Small Molecule Blocker of the Large-Conductance Voltage-Gated and Calcium-Dependent K+ Channel
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1-[1-Hexyl-6-(methyloxy)-1H-indazol-3-yl]-2-methyl-1-propanone, a Potent and Highly Selective Small Molecule Blocker of the Large-Conductance Voltage-Gated and Calcium-Dependent K+ Channel

Zeng, Haoyu ; Gordon, Earl ; Lin, Zuojun ; Lozinskaya, Irina M ; Willette, Robert N ; Xu, Xiaoping

The Journal of pharmacology and experimental therapeutics, 2008-10, Vol.327 (1), p.168-177 [Periódico revisado por pares]

United States: American Society for Pharmacology and Experimental Therapeutics

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4
1-[(1-Methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 Positive Allosteric Modulators for the Treatment of Psychosis
1-[(1-Methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 Positive Allosteric Modulators for the Treatment of Psychosis
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1-[(1-Methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 Positive Allosteric Modulators for the Treatment of Psychosis

Zhang, Lei ; Brodney, Michael A ; Candler, John ; Doran, Angela C ; Duplantier, Allen J ; Efremov, Ivan V ; Evrard, Edel ; Kraus, Kenneth ; Ganong, Alan H ; Haas, Jessica A ; Hanks, Ashley N ; Jenza, Keith ; Lazzaro, John T ; Maklad, Noha ; McCarthy, Sheryl A ; Qian, Weimin ; Rogers, Bruce N ; Rottas, Melinda D ; Schmidt, Christopher J ; Siuciak, Judith A ; Tingley, F. David ; Zhang, Andy Q

Journal of medicinal chemistry, 2011-03, Vol.54 (6), p.1724-1739 [Periódico revisado por pares]

United States: American Chemical Society

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5
1-(1-naphthyl)-piperazine, a mixed 5-HT1A and 5-HT2A/2C receptor ligand, elicits an anxiolytic-like effect in the open-field test without changes in 5-HT metabolism
1-(1-naphthyl)-piperazine, a mixed 5-HT1A and 5-HT2A/2C receptor ligand, elicits an anxiolytic-like effect in the open-field test without changes in 5-HT metabolism
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1-(1-naphthyl)-piperazine, a mixed 5-HT1A and 5-HT2A/2C receptor ligand, elicits an anxiolytic-like effect in the open-field test without changes in 5-HT metabolism

PRUUS, K ; RUDISAAR, R ; VAARMANN, A ; MATTO, V ; ALLIKMETS, L

Methods and findings in experimental and clinical pharmacology, 2002-04, Vol.24 (3), p.151-157 [Periódico revisado por pares]

Barcelona: Prous

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6
1-(1,3-Benzodioxol-5-yl-carbo-nyl) Piperidine, a Modulator of α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor, Ameliorates Exercise-Induced Fatigue in Mice
1-(1,3-Benzodioxol-5-yl-carbo-nyl) Piperidine, a Modulator of α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor, Ameliorates Exercise-Induced Fatigue in Mice
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1-(1,3-Benzodioxol-5-yl-carbo-nyl) Piperidine, a Modulator of α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor, Ameliorates Exercise-Induced Fatigue in Mice

Fan, Wutu ; Wu, Xianglong ; Pan, Yalei ; Li, Chenrui ; Niu, Yinbo ; Zhai, Yuankun ; Mei, Qibing

Biological and Pharmaceutical Bulletin, 2014/01/01, Vol.37(1), pp.13-17 [Periódico revisado por pares]

Japan: The Pharmaceutical Society of Japan

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7
1-(1,3-Benzodioxol-5-ylmethyl)-3-[4-(1 H-imidazol-1-yl)phenoxy]-piperidine analogs as potent and selective inhibitors of nitric oxide formation
1-(1,3-Benzodioxol-5-ylmethyl)-3-[4-(1 H-imidazol-1-yl)phenoxy]-piperidine analogs as potent and selective inhibitors of nitric oxide formation
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1-(1,3-Benzodioxol-5-ylmethyl)-3-[4-(1 H-imidazol-1-yl)phenoxy]-piperidine analogs as potent and selective inhibitors of nitric oxide formation

Wei, Robert G. ; Adler, Marc ; Davey, David ; Ho, Elena ; Mohan, Raju ; Polokoff, Mark ; Tseng, Jih-Lie ; Whitlow, Marc ; Xu, Wei ; Yuan, Shendong ; Phillips, Gary

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (9), p.2499-2504 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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8
1,1-Bis (3′-indolyl)-1-(p-substitutedphenyl)methane compounds inhibit lung cancer cell and tumor growth in a metastasis model
1,1-Bis (3′-indolyl)-1-(p-substitutedphenyl)methane compounds inhibit lung cancer cell and tumor growth in a metastasis model
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1,1-Bis (3′-indolyl)-1-(p-substitutedphenyl)methane compounds inhibit lung cancer cell and tumor growth in a metastasis model

Andey, Terrick ; Patel, Apurva ; Jackson, Tanise ; Safe, Stephen ; Singh, Mandip

European journal of pharmaceutical sciences, 2013-10, Vol.50 (2), p.227-241 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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9
1,1-Bisphosphonate Squalene Synthase Inhibitors: Interplay Between the Isoprenoid Subunit and the Diphosphate Surrogate
1,1-Bisphosphonate Squalene Synthase Inhibitors: Interplay Between the Isoprenoid Subunit and the Diphosphate Surrogate
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1,1-Bisphosphonate Squalene Synthase Inhibitors: Interplay Between the Isoprenoid Subunit and the Diphosphate Surrogate

Magnin, David R ; Dickson, John K ; Logan, Janette V ; Lawrence, R. Michael ; Chen, Ying ; Sulsky, Richard B ; Ciosek, Carl P ; Biller, Scott A ; Harrity, Thomas W ; Jolibois, Kern G ; Kunselman, Lori K ; Rich, Lois C ; Slusarchyk, Dorothy A

Journal of medicinal chemistry, 1995-07, Vol.38 (14), p.2596-2605 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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10
1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4
1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4
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1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4

Ruchelman, Alexander L. ; Man, Hon-Wah ; Chen, Roger ; Liu, Wei ; Lu, Ling ; Cedzik, Dorota ; Zhang, Ling ; Leisten, Jim ; Collette, Alice ; Narla, Rama Krishna ; Raymon, Heather K. ; Muller, George W.

Bioorganic & medicinal chemistry, 2011-11, Vol.19 (21), p.6356-6374 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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