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Refinado por: assunto: Life Sciences & Biomedicine remover
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1
1-(2-(2,2,2-trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors
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1-(2-(2,2,2-trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors

Tollefson, Michael B ; Acker, Brad A ; Jacobsen, E J ; Hughes, Robert O ; Walker, John K ; Fox, David N A ; Palmer, Michael J ; Freeman, Sandra K ; Yu, Ying ; Bond, Brian R

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3125-3128 [Periódico revisado por pares]

England

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2
1-(2-Deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent
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1-(2-Deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent

Mansuri, Muzammil M ; Ghazzouli, Ismail ; Chen, Ming S ; Howell, Henry G ; Brodfuehrer, Paul R ; Benigni, Daniel A ; Martin, John C

Journal of medicinal chemistry, 1987-05, Vol.30 (5), p.867-871 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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3
1-(2-Ethoxyethyl)-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors
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1-(2-Ethoxyethyl)-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors

TOLLEFSON, Michael B ; ACKER, Brad A ; JACOBSEN, E. J ; HUGHES, Robert O ; WALKER, John K ; FOX, David N. A ; PALMER, Michael J ; FREEMAN, Sandra K ; YING YU ; BOND, Brian R

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3120-3124 [Periódico revisado por pares]

Amsterdam: Elsevier

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4
1-(2,3-Anhydro-.beta.-D-lyxofuranosyl)cytosine derivatives as potential inhibitors of the human immunodeficiency virus
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1-(2,3-Anhydro-.beta.-D-lyxofuranosyl)cytosine derivatives as potential inhibitors of the human immunodeficiency virus

Webb, Thomas R ; Mitsuya, Hiroaki ; Broder, Samuel

Journal of medicinal chemistry, 1988-07, Vol.31 (7), p.1475-1479 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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5
1,000-loci transcript map of the barley genome: new anchoring points for integrative grass genomics
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1,000-loci transcript map of the barley genome: new anchoring points for integrative grass genomics

Stein, Nils ; Prasad, Manoj ; Scholz, Uwe ; Thiel, Thomas ; Zhang, Hangning ; Wolf, Markus ; Kota, Raja ; Varshney, Rajeev K ; Perovic, Dragan ; Grosse, Ivo ; Graner, Andreas

Theoretical and applied genetics, 2007-03, Vol.114 (5), p.823-839 [Periódico revisado por pares]

Heidelberg: Berlin/Heidelberg : Springer-Verlag

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6
1,000 structures and more from the MCSG
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1,000 structures and more from the MCSG

Lee, David ; de Beer, Tjaart A P ; Laskowski, Roman A ; Thornton, Janet M ; Orengo, Christine A

BMC structural biology, 2011-01, Vol.11 (1), p.2-2 [Periódico revisado por pares]

England: BioMed Central Ltd

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7
1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life
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1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life

Mukherjee, Supratim ; Seshadri, Rekha ; Varghese, Neha J ; Eloe-Fadrosh, Emiley A ; Meier-Kolthoff, Jan P ; Göker, Markus ; Coates, R Cameron ; Hadjithomas, Michalis ; Pavlopoulos, Georgios A ; Paez-Espino, David ; Yoshikuni, Yasuo ; Visel, Axel ; Whitman, William B ; Garrity, George M ; Eisen, Jonathan A ; Hugenholtz, Philip ; Pati, Amrita ; Ivanova, Natalia N ; Woyke, Tanja ; Klenk, Hans-Peter ; Kyrpides, Nikos C

Nature biotechnology, 2017-07, Vol.35 (7), p.676-683 [Periódico revisado por pares]

United States: Nature Publishing Group

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8
1+1 = 3: a fusion of 2 enzymes in the methionine salvage pathway of Tetrahymena thermophila creates a trifunctional enzyme that catalyzes 3 steps in the pathway
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1+1 = 3: a fusion of 2 enzymes in the methionine salvage pathway of Tetrahymena thermophila creates a trifunctional enzyme that catalyzes 3 steps in the pathway

Salim, Hannah M W ; Negritto, Maria Cristina ; Cavalcanti, Andre R O Dutcher, Susan K.

PLoS genetics, 2009-10, Vol.5 (10), p.e1000701-e1000701 [Periódico revisado por pares]

United States: Public Library of Science

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9
1,1-bis(3′-indolyl)-1-(p-substituted phenyl)methanes decrease mitochondrial membrane potential and induce apoptosis in endometrial and other cancer cell lines
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1,1-bis(3′-indolyl)-1-(p-substituted phenyl)methanes decrease mitochondrial membrane potential and induce apoptosis in endometrial and other cancer cell lines

Hong, Jun ; Samudio, Ismael ; Chintharlapalli, Sudhakar ; Safe, Stephen

Molecular carcinogenesis, 2008-07, Vol.47 (7), p.492-507 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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10
1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4
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1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4

Ruchelman, Alexander L. ; Man, Hon-Wah ; Chen, Roger ; Liu, Wei ; Lu, Ling ; Cedzik, Dorota ; Zhang, Ling ; Leisten, Jim ; Collette, Alice ; Narla, Rama Krishna ; Raymon, Heather K. ; Muller, George W.

Bioorganic & medicinal chemistry, 2011-11, Vol.19 (21), p.6356-6374 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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