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1 |
Material Type: Artigo
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1-(2-(2,2,2-trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitorsTollefson, Michael B ; Acker, Brad A ; Jacobsen, E J ; Hughes, Robert O ; Walker, John K ; Fox, David N A ; Palmer, Michael J ; Freeman, Sandra K ; Yu, Ying ; Bond, Brian RBioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3125-3128 [Periódico revisado por pares]EnglandTexto completo disponível |
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Material Type: Artigo
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1-(2-Deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agentMansuri, Muzammil M ; Ghazzouli, Ismail ; Chen, Ming S ; Howell, Henry G ; Brodfuehrer, Paul R ; Benigni, Daniel A ; Martin, John CJournal of medicinal chemistry, 1987-05, Vol.30 (5), p.867-871 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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1-(2-Ethoxyethyl)-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitorsTOLLEFSON, Michael B ; ACKER, Brad A ; JACOBSEN, E. J ; HUGHES, Robert O ; WALKER, John K ; FOX, David N. A ; PALMER, Michael J ; FREEMAN, Sandra K ; YING YU ; BOND, Brian RBioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3120-3124 [Periódico revisado por pares]Amsterdam: ElsevierTexto completo disponível |
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Material Type: Artigo
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1-(2,3-Anhydro-.beta.-D-lyxofuranosyl)cytosine derivatives as potential inhibitors of the human immunodeficiency virusWebb, Thomas R ; Mitsuya, Hiroaki ; Broder, SamuelJournal of medicinal chemistry, 1988-07, Vol.31 (7), p.1475-1479 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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1,000-loci transcript map of the barley genome: new anchoring points for integrative grass genomicsStein, Nils ; Prasad, Manoj ; Scholz, Uwe ; Thiel, Thomas ; Zhang, Hangning ; Wolf, Markus ; Kota, Raja ; Varshney, Rajeev K ; Perovic, Dragan ; Grosse, Ivo ; Graner, AndreasTheoretical and applied genetics, 2007-03, Vol.114 (5), p.823-839 [Periódico revisado por pares]Heidelberg: Berlin/Heidelberg : Springer-VerlagTexto completo disponível |
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Material Type: Artigo
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1,000 structures and more from the MCSGLee, David ; de Beer, Tjaart A P ; Laskowski, Roman A ; Thornton, Janet M ; Orengo, Christine ABMC structural biology, 2011-01, Vol.11 (1), p.2-2 [Periódico revisado por pares]England: BioMed Central LtdTexto completo disponível |
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Material Type: Artigo
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1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of lifeMukherjee, Supratim ; Seshadri, Rekha ; Varghese, Neha J ; Eloe-Fadrosh, Emiley A ; Meier-Kolthoff, Jan P ; Göker, Markus ; Coates, R Cameron ; Hadjithomas, Michalis ; Pavlopoulos, Georgios A ; Paez-Espino, David ; Yoshikuni, Yasuo ; Visel, Axel ; Whitman, William B ; Garrity, George M ; Eisen, Jonathan A ; Hugenholtz, Philip ; Pati, Amrita ; Ivanova, Natalia N ; Woyke, Tanja ; Klenk, Hans-Peter ; Kyrpides, Nikos CNature biotechnology, 2017-07, Vol.35 (7), p.676-683 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
8 |
Material Type: Artigo
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1+1 = 3: a fusion of 2 enzymes in the methionine salvage pathway of Tetrahymena thermophila creates a trifunctional enzyme that catalyzes 3 steps in the pathwaySalim, Hannah M W ; Negritto, Maria Cristina ; Cavalcanti, Andre R O Dutcher, Susan K.PLoS genetics, 2009-10, Vol.5 (10), p.e1000701-e1000701 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
9 |
Material Type: Artigo
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1,1-bis(3′-indolyl)-1-(p-substituted phenyl)methanes decrease mitochondrial membrane potential and induce apoptosis in endometrial and other cancer cell linesHong, Jun ; Samudio, Ismael ; Chintharlapalli, Sudhakar ; Safe, StephenMolecular carcinogenesis, 2008-07, Vol.47 (7), p.492-507 [Periódico revisado por pares]Hoboken: Wiley Subscription Services, Inc., A Wiley CompanyTexto completo disponível |
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Material Type: Artigo
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1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4Ruchelman, Alexander L. ; Man, Hon-Wah ; Chen, Roger ; Liu, Wei ; Lu, Ling ; Cedzik, Dorota ; Zhang, Ling ; Leisten, Jim ; Collette, Alice ; Narla, Rama Krishna ; Raymon, Heather K. ; Muller, George W.Bioorganic & medicinal chemistry, 2011-11, Vol.19 (21), p.6356-6374 [Periódico revisado por pares]Amsterdam: Elsevier LtdTexto completo disponível |