Stress-Specific Activation of Heat Shock Factor (HSF) and Hypoxia-Inducible Factor (HIF) in the Kidney

Eickelberg, Oliver ; Seebach, Frank ; Thulin, Gunilla ; Van Why, Scott K ; Kashgarian, Michael ; Siegel, Norman J

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Thresholds for cellular disruption and activation of the stress response in renal epithelia

van Why, Scott K ; Kim, Sunmi ; Geibel, John ; Seebach, Frank A ; Kashgarian, Michael ; Siegel, Norman J

United States

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Therapeutic vaccination reduces HIV sequence variability

Hoffmann, Dieter ; Seebach, Judith ; Cosma, Antonio ; Goebel, Frank D ; Strimmer, Korbinian ; Schätzl, Hermann M ; Erfle, Volker

United States: The Federation of American Societies for Experimental Biology

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PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma

Migden, Michael R ; Rischin, Danny ; Schmults, Chrysalyne D ; Guminski, Alexander ; Hauschild, Axel ; Lewis, Karl D ; Chung, Christine H ; Hernandez-Aya, Leonel ; Lim, Annette M ; Chang, Anne Lynn S ; Rabinowits, Guilherme ; Thai, Alesha A ; Dunn, Lara A ; Hughes, Brett G.M ; Khushalani, Nikhil I ; Modi, Badri ; Schadendorf, Dirk ; Gao, Bo ; Seebach, Frank ; Li, Siyu ; Li, Jingjin ; Mathias, Melissa ; Booth, Jocelyn ; Mohan, Kosalai ; Stankevich, Elizabeth ; Babiker, Hani M ; Brana, Irene ; Gil-Martin, Marta ; Homsi, Jade ; Johnson, Melissa L ; Moreno, Victor ; Niu, Jiaxin ; Owonikoko, Taofeek K ; Papadopoulos, Kyriakos P ; Yancopoulos, George D ; Lowy, Israel ; Fury, Matthew G

United States: Massachusetts Medical Society

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A phase I/II study of REGN5093, a MET x MET bispecific antibody, in patients with MET-altered advanced non-small cell lung cancer (NSCLC)

Rowlands, Tracey ; Boyapati, Anita ; Li, Siyu ; Daly, Christopher ; Seebach, Frank A. ; Lowy, Israel ; Rietschel, Petra

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A phase I/II study of REGN5678 (Anti-PSMAxCD28, a costimulatory bispecific antibody) with cemiplimab (anti-PD-1) in patients with metastatic castration-resistant prostate cancer

Drake, Charles G. ; Zhang, Jingsong ; Stein, Mark N. ; Xu, Yuanfang ; Seebach, Frank A. ; Lowy, Israel ; Mohan, Kosalai Kal ; Kroog, Glenn ; Miller, Elizabeth

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Phase II trial of Voyager-V1 (vesicular stomatitis virus expressing human IFNβ and NIS, VV1), in combination with cemiplimab (C) in patients with NSCLC, melanoma, HCC or endometrial carcinoma

Sznol, Mario ; Lutzky, Jose ; Adjei, Alex A. ; Powell, Steven Francis ; He, Aiwu Ruth ; Patel, Manish ; O'Day, Steven ; Pandya, Naimish B. ; Kaesshaefer, Stephen ; Reckner, Monica ; Brown, Cheryl ; Diaz, Rosa M ; Russell, Luke ; Peng, Kah Whye ; Wiegert, Erol ; Gullo, Giuseppe ; Seebach, Frank A. ; Lowy, Israel ; Bexon, Alice Susannah

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Madduri, Deepu ; Rosko, Ashley ; Brayer, Jason ; Zonder, Jeffrey ; Bensinger, William I. ; Li, Jingjin ; Xu, Linzhi ; Adriaens, Lieve ; Chokshi, Dhruti ; Zhang, Weijiang ; Boyapati, Anita ; Sharma, Manish ; Seebach, Frank ; Sirulnik, L. Andres ; Weinreich, David M. ; Yancopoulos, George D. ; Dhodapkar, Madhav V. ; Lentzsch, Suzanne ; Cooper, Dennis ; Jagannath, Sundar

Elsevier Inc

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Phase 2 open-label, multicenter, single-arm study of cemiplimab in patients with locally advanced basal cell carcinoma after hedgehog inhibitor therapy: Extended follow-up

Stratigos, Alexander J ; Sekulic, Aleksandar ; Peris, Ketty ; Bechter, Oliver ; Prey, Sorilla ; Lewis, Karl D ; Basset-Seguin, Nicole ; Chang, Anne Lynn S ; Dalle, Stephane ; Orland, Almudena Fernandez ; Licitra, Lisa ; Robert, Caroline ; Ulrich, Claas ; Hauschild, Axel ; Migden, Michael R ; Dummer, Reinhard ; Yoo, Suk-Young ; Okoye, Emmanuel ; Bassukas, Ioannis ; Loquai, Carmen ; De Giorgi, Vincenzo ; Eroglu, Zeynep ; Gutzmer, Ralf ; Ulrich, Jens ; Puig, Susana ; Inocencio, Timothy J ; Chen, Chieh ; Lafontaine, Patrick R ; Seebach, Frank ; Lowy, Israel ; Fury, Matthew G

MOSBY-ELSEVIER

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Cemiplimab monotherapy for first-line treatment of advanced non-small-cell lung cancer with PD-L1 of at least 50%: a multicentre, open-label, global, phase 3, randomised, controlled trial

Sezer, Ahmet ; Kilickap, Saadettin ; Gümüş, Mahmut ; Bondarenko, Igor ; Özgüroğlu, Mustafa ; Gogishvili, Miranda ; Turk, Haci M ; Cicin, Irfan ; Bentsion, Dmitry ; Gladkov, Oleg ; Clingan, Philip ; Sriuranpong, Virote ; Rizvi, Naiyer ; Gao, Bo ; Li, Siyu ; Lee, Sue ; McGuire, Kristina ; Chen, Chieh-I ; Makharadze, Tamta ; Paydas, Semra ; Nechaeva, Marina ; Seebach, Frank ; Weinreich, David M ; Yancopoulos, George D ; Gullo, Giuseppe ; Lowy, Israel ; Rietschel, Petra

England: Elsevier Ltd

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