Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis

Berchuck, Jacob E ; Baca, Sylvan C ; McClure, Heather M ; Korthauer, Keegan ; Tsai, Harrison K ; Nuzzo, Pier Vitale ; Kelleher, Kaitlin M ; He, Monica ; Steinharter, John A ; Zacharia, Soumya ; Spisak, Sandor ; Seo, Ji-Heui ; Conteduca, Vincenza ; Elemento, Olivier ; Auh, Joonghoon ; Sigouros, Michael ; Corey, Eva ; Hirsch, Michelle S ; Taplin, Mary-Ellen ; Choueiri, Toni K ; Pomerantz, Mark M ; Beltran, Himisha ; Freedman, Matthew L

United States

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Abstract AP11: IDENTIFYING FUNCTIONAL NONCODING SOMATIC MUTATIONS IN OVARIAN CANCER

Corona, Rosario I. ; Seo, Ji-Heui ; Hazelett, Dennis J. ; Lin, Xianzhi ; Mhawech-Fauceglia, Paulette Y. ; Lester, Jenny ; Shah, Sohrab P. ; Huntsman, David G. ; Karlan, Beth Y. ; Gusev, Alexander ; Berman, Benjamin P. ; Freedman, Matthew L. ; Gayther, Simon A. ; Lawrenson, Kate

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Detecting small cell transformation in patients with advanced EGFR mutant lung adenocarcinoma through epigenomic cfDNA profiling

El Zarif, Talal ; Meador, Catherine B. ; Qiu, Xintao ; Seo, Ji-Heui ; Davidsohn, Matthew P. ; Savignano, Hunter ; Lakshminarayanan, Gitanjali ; McClure, Heather M. ; Canniff, John ; Fortunato, Brad ; Li, Rong ; Banwait, Mandeep K. ; Semaan, Karl ; Eid, Marc ; Long, Henry ; Hung, Yin P. ; Mahadevan, Navin R. ; Barbie, David A. ; Oser, Matthew G. ; Piotrowska, Zofia ; Choueiri, Toni K. ; Baca, Sylvan C. ; Hata, Aaron N. ; Freedman, Matthew L. ; Berchuck, Jacob E.

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A Novel Mechanism Driving Poor-Prognosis Prostate Cancer: Overexpression of the DNA Repair Gene, Ribonucleotide Reductase Small Subunit M2 (RRM2)

Mazzu, Ying Z ; Armenia, Joshua ; Chakraborty, Goutam ; Yoshikawa, Yuki ; Coggins, Si'Ana A ; Nandakumar, Subhiksha ; Gerke, Travis A ; Pomerantz, Mark M ; Qiu, Xintao ; Zhao, Huiyong ; Atiq, Mohammad ; Khan, Nabeela ; Komura, Kazumasa ; Lee, Gwo-Shu Mary ; Fine, Samson W ; Bell, Connor ; O'Connor, Edward ; Long, Henry W ; Freedman, Matthew L ; Kim, Baek ; Kantoff, Philip W

United States

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Abstract GMM-042: PAN-CANCER TRANSCRIPTION FACTOR ANALYSES IDENTIFY ZNF217 AS A NOVEL DRIVER IN HGSOC

Nameki, Robbin ; Fonseca, Marcos A. S. ; Reddy, Jessica ; Vavra, Kevin C. ; Segato, Felipe ; Corona, Rosario I. ; Seo, Ji-Heui ; Liu, Annie ; Abbasi, Forough ; Lin, Xianzhi ; Karlan, Beth Y. ; Freedman, Matthew L. ; Gayther, Simon A. ; Noushmehr, Houtan ; Lawrenson, Kate

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Evaluation of 8q24 and 17q Risk Loci and Prostate Cancer Mortality

PENNEY, Kathryn L ; SALINAS, Claudia A ; JING MA ; MUCCI, Lorelei ; STANFORD, Janet L ; KANTOFF, Philip W ; HUNTER, David J ; STAMPFER, Meir J ; FREEDMAN, Matthew L ; POMERANTZ, Mark ; SCHUMACHER, Fredrick R ; BECKWITH, Christine A ; LEE, Gwo-Shu ; OH, William K ; SARTOR, Oliver ; OSTRANDER, Elaine A ; KURTH, Tobias

Philadelphia, PA: American Association for Cancer Research

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Detection of Molecular Signatures of Homologous Recombination Deficiency in Prostate Cancer with or without BRCA1/2 Mutations

Sztupinszki, Zsofia ; Diossy, Miklos ; Krzystanek, Marcin ; Borcsok, Judit ; Pomerantz, Mark M ; Tisza, Viktoria ; Spisak, Sandor ; Rusz, Orsolya ; Csabai, István ; Freedman, Matthew L ; Szallasi, Zoltan

United States

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Inherited Variants in the Chemokine CCL2 Gene and Prostate Cancer Aggressiveness in a Caucasian Cohort

TONG SUN ; LEE, Gwo-Shu Mary ; OH, William K ; FREEDMAN, Matthew L ; POMERANTZ, Mark ; PIENTA, Kenneth J ; KANTOFF, Philip W

Philadelphia, PA: American Association for Cancer Research

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Single-Nucleotide Polymorphisms in p53 Pathway and Aggressiveness of Prostate Cancer in a Caucasian Population

TONG SUN ; MARY LEE, Gwo-Shu ; OH, William K ; POMERANTZ, Mark ; MING YANG ; WANLING XIE ; FREEDMAN, Matthew L ; KANTOFF, Philip W

Philadelphia, PA: American Association for Cancer Research

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