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1 |
Material Type: Artigo
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1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modelling StudiesSoares, Pedro ; Costa, Raquel ; Froufe, Hugo J. C. ; Calhelha, Ricardo C. ; Peixoto, Daniela ; Ferreira, Isabel C. F. R. ; Abreu, Rui M. V. ; Soares, Raquel ; Queiroz, Maria-João R. P. Domene, CarmenBioMed research international, 2013-01, Vol.2013, p.154856-9 [Periódico revisado por pares]United States: Hindawi Publishing CorporationTexto completo disponível |
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Material Type: Artigo
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104-week efficacy and safety of cipaglucosidase alfa plus miglustat in adults with late-onset Pompe disease: a phase III open-label extension study (ATB200-07)Schoser, Benedikt ; Kishnani, Priya S. ; Bratkovic, Drago ; Byrne, Barry J. ; Claeys, Kristl G. ; Díaz-Manera, Jordi ; Laforêt, Pascal ; Roberts, Mark ; Toscano, Antonio ; van der Ploeg, Ans T. ; Castelli, Jeff ; Goldman, Mitchell ; Holdbrook, Fred ; Sitaraman Das, Sheela ; Wasfi, Yasmine ; Mozaffar, TahseenJournal of neurology, 2024-05, Vol.271 (5), p.2810-2823 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Material Type: Artigo
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1,3,8-Trisubstituted xanthines. Effects of substitution pattern upon adenosine receptor A1/A2 affinityErickson, Ronald H ; Hiner, Roger N ; Feeney, Scott W ; Blake, Paul R ; Rzeszotarski, Waclaw J ; Hicks, Rickey P ; Costello, Diane G ; Abreu, Mary EJournal of medicinal chemistry, 1991-04, Vol.34 (4), p.1431-1435 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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20-Epiheyneanine, an iboga alkaloid from Peschiera affinisAbreu Matos, Francisco J. ; Braz Fo, Raimundo ; Gottlieb, Otto R. ; Welbaneide, F. ; Machado, L. ; Iracema, M. ; Madruga, L.M.Phytochemistry (Oxford), 1976, Vol.15 (4), p.551-553 [Periódico revisado por pares]Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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24(S),25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivoTheofilopoulos, Spyridon ; Abreu de Oliveira, Willy Antoni ; Yang, Shanzheng ; Yutuc, Eylan ; Saeed, Ahmed ; Abdel-Khalik, Jonas ; Ullgren, Abbe ; Cedazo-Minguez, Angel ; Björkhem, Ingemar ; Wang, Yuqin ; Griffiths, William J. ; Arenas, ErnestThe Journal of biological chemistry, 2019-03, Vol.294 (11), p.4169-4176 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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25 de Abril Sempre! Portuguese Science and the 50th anniversary of the Carnation RevolutionDantas, Tiago ; Abreu, Carla M C ; De-Castro, Maria J G ; Grosso, Ana Rita ; de Sousa Valente, Joao ; da Silva Xavier, GabrielaCommunications biology, 2024-05, Vol.7 (1), p.537-537, Article 537 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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2,8-Dihydroxyadenine Stone Formation in a Renal Transplant Recipient due to Adenine Phosphoribosyltransferase DeficiencyDe Jong, Dirk J. ; Assmann, Karel J.M. ; De Abreu, Ronney A. ; Monnens, Leo A.H. ; Van Liebergen, Frans J.H.M. ; Dijkman, Henri B.P.M. ; Huysmans, Frans T.M.The Journal of urology, 1996-11, Vol.156 (5), p.1754-1755 [Periódico revisado por pares]Hagerstown, MD: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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2,8-Dihydroxyadenine Urolithiasis in a Patient with Considerable Residual Adenine Phosphoribosyltransferase Activity in Cell Extracts but with Mutations in Both Copies of APRTDeng, Li ; Yang, Min ; Fründ, Stefan ; Wessel, Torsten ; De Abreu, Ronney A ; Tischfield, Jay A ; Sahota, AmrikMolecular genetics and metabolism, 2001-03, Vol.72 (3), p.260-264 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific RecognitionMajellaro, María ; Jespers, Willem ; Crespo, Abel ; Núñez, María J ; Novio, Silvia ; Azuaje, Jhonny ; Prieto-Díaz, Rubén ; Gioé, Claudia ; Alispahic, Belma ; Brea, José ; Loza, María I ; Freire-Garabal, Manuel ; Garcia-Santiago, Carlota ; Rodríguez-García, Carlos ; García-Mera, Xerardo ; Caamaño, Olga ; Fernandez-Masaguer, Christian ; Sardina, Javier F ; Stefanachi, Angela ; El Maatougui, Abdelaziz ; Mallo-Abreu, Ana ; Åqvist, Johan ; Gutiérrez-de-Terán, Hugo ; Sotelo, EddyJournal of medicinal chemistry, 2021-01, Vol.64 (1), p.458-480 [Periódico revisado por pares]Texto completo disponível |
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Material Type: Artigo
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4D MEMRI atlas of neonatal FVB/N mouse brain developmentSzulc, Kamila U. ; Lerch, Jason P. ; Nieman, Brian J. ; Bartelle, Benjamin B. ; Friedel, Miriam ; Suero-Abreu, Giselle A. ; Watson, Charles ; Joyner, Alexandra L. ; Turnbull, Daniel H.NeuroImage (Orlando, Fla.), 2015-09, Vol.118, p.49-62 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |