Abstract CT235: A phase I/II clinical study of an oncolytic adenovirus expressing the immunostimulatory transgenes TMZ-CD40L and 4-1BBL in advanced solid malignancies

Hahn, Amanda ; Irenaeus, Sandra ; Wenthe, Jessica ; Eriksson, Emma ; Schiza, Aglaia ; Dahlstrand, Hanna ; Olsson-Strömberg, Ulla ; Krause, Johan ; Sundin, Anders ; Sandin, Linda ; Jarblad, Justyna Leja ; Liljefors, Maria Gustafsson ; Rowinsky, Eric ; Loskog, Angelica ; Ullenhag, Gustav J.

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Abstract 5524: Persistent patient barriers to genomic testing in ambulatory oncology

Haakenstad, Ellana K. ; Roberts, Jane ; Revette, Anna C. ; Loeser, Wendy ; Grider, Joseph ; Kruse, Andrea ; Gentile, Alissa ; Freedman, Rachel ; Lindeman, Neal I. ; Kozyreva, Olga ; Sanz-Altamira, Pedro ; Lathan, Christopher S. ; Hassett, Michael ; Cerami, Ethan ; Kim, Annette S. ; Manning, Danielle K. ; Nowak, Jonathan ; Giannakis, Marios ; Lindsley, R Coleman ; Hahn, William C. ; Rollins, Barrett J. ; Garraway, Levi ; Johnson, Bruce E. ; McCleary, Nadine Jackson

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Abstract 612: Control of the Basal Molecular Subtype of Murine Bladder Cancer by Adaptive Immunity

Johnson, Burles Avner ; Feng, Mingxiao ; Choi, Woonyoung ; Colocho, Gabriela ; Arbuiso, Alyssa ; Jin, Samuel ; Aragaki, Adam K. ; Ruland, Charles ; Rapiey, Stanley ; Hahn, Noah M. ; McConkey, David J.

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Spatially-resolved single-cell assessment of pancreatic cancer expression subtypes reveals co-expressor phenotypes and extensive intra-tumoral heterogeneity

Williams, Hannah L. ; Dias Costa, Andressa ; Zhang, Jinming ; Raghavan, Srivatsan ; Winter, Peter S. ; Kapner, Kevin S. ; Ginebaugh, Scott P. ; Väyrynen, Sara A. ; Väyrynen, Juha P. ; Yuan, Chen ; Navia, Andrew W. ; Wang, Junning ; Yang, Annan ; Bosse, Timothy L. ; Kalekar, Radha L. ; Lowder, Kristen E. ; Lau, Mai Chan ; Elganainy, Dalia ; Morales-Oyarvide, Vicente ; Rubinson, Douglas A. ; Singh, Harshabad ; Perez, Kimberly ; Cleary, James M. ; Clancy, Thomas E. ; Wang, Jiping ; Mancias, Joseph D. ; Brais, Lauren K. ; Hill, Emma R. ; Kozak, Margaret M. ; Linehan, David C. ; Dunne, Richard F. ; Chang, Daniel T. ; Koong, Albert C. ; Hezel, Aram F. ; Hahn, William C. ; Shalek, Alex K. ; Aguirre, Andrew J. ; Nowak, Jonathan A. ; Wolpin, Brian M.

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Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity

Williams, Hannah L ; Dias Costa, Andressa ; Zhang, Jinming ; Raghavan, Srivatsan ; Winter, Peter S ; Kapner, Kevin S ; Ginebaugh, Scott P ; Väyrynen, Sara A ; Väyrynen, Juha P ; Yuan, Chen ; Navia, Andrew W ; Wang, Junning ; Yang, Annan ; Bosse, Timothy L ; Kalekar, Radha L ; Lowder, Kristen E ; Lau, Mai Chan ; Elganainy, Dalia ; Morales-Oyarvide, Vicente ; Rubinson, Douglas A ; Singh, Harshabad ; Perez, Kimberly ; Cleary, James M ; Clancy, Thomas E ; Wang, Jiping ; Mancias, Joseph D ; Brais, Lauren K ; Hill, Emma R ; Kozak, Margaret M ; Linehan, David C ; Dunne, Richard F ; Chang, Daniel T ; Koong, Albert C ; Hezel, Aram F ; Hahn, William C ; Shalek, Alex K ; Aguirre, Andrew J ; Nowak, Jonathan A ; Wolpin, Brian M

United States

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Abstract 1281: SGN-B7H4V shows immunomodulatory activity through induction of immunogenic cell death

Gray, Elizabeth E. ; Ulrich, Michelle ; Epp, Angela ; Younan, Patrick ; Hensley, Kelly ; Allred, Sean ; Hahn, Julie ; Gahnberg, Kristen ; Treuting, Piper M. ; Gosink, John J. ; Thurman, Robert ; Smith, Alyson J. ; Schrum, Jason ; Nazarenko, Natalya ; Gardai, Shyra J.

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Abstract 1028: Phosphate dysregulation as a novel therapeutic strategy in ovarian and uterine cancers

Bondeson, Daniel ; Paolella, Brenton ; Asfaw, Adhana ; Rothberg, Michael ; Skipper, Thomas ; Mesa, Gabriel ; Gonzalez, Alfredo ; Surface, Lauren E. ; Ito, Kentaro ; Kazachkova, Mariya ; Colgan, William N. ; Warren, Allie ; Dempster, Joshua ; Krill-Burger, J Michael ; Ericsson, Maria ; Tang, Andrew ; Fung, Iris ; Chambers, Emily S. ; Abdusamad, Mai ; Dumont, Nancy ; Doench, John ; Piccioni, Federica ; Root, David ; Boehm, Jesse ; Hahn, William C. ; Mannstadt, Michael ; McFarland, James ; Vazquez, Francisca ; Golub, Todd

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Abstract CT026: The effect of intrinsic subtype on inhibition of tumor growth by anastrozole vs. fulvestrant vs. the combination: Results from the Alliance neoadjuvant endocrine therapy (NET) ALTERNATE trial

Ellis, Matthew J. ; Anurag, Meenakshi ; Hoog, Jeremy ; Fernandez-Martinez, Aranzazu ; Fan, Cheng ; Gibbs, Richard ; Sanati, Souzan ; Vij, Kiran ; Watson, Mark ; Dockter, Travis ; Hahn, Olwen ; Guenther, Joseph ; Caudle, Abigail ; Crouch, Erica ; Tiersten, Amy ; Mita, Monica ; Razaq, Wajeeha ; Hieken, Tina J. ; Wang, Yang ; Leitch, A. Marilyn ; Unzeitig, Gary W. ; Winer, Eric ; Weiss, Anna ; Hunt, Kelly ; Partridge, Ann H. ; Perou, Charles M. ; Suman, Vera ; Ma, Cynthia X. ; Carey, Lisa A.

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Abstract PD9-03: Pam50 intrinsic subtype and risk of recurrence score (ROR) for the prediction of endocrine (ET) sensitivity and pathologic response to chemotherapy in postmenopausal women with clinical stage II/III estrogen receptor positive (ER+) and HER2 negative (HER2-) breast cancer (BC) in the alternate trial (Alliance A011106)

Ma, Cynthia X ; Anurag, Meenakshi ; Dockter, Travis ; Hoog, Jeremy ; Fernandez-Martinez, Aranzazu ; Fan, Cheng ; Gibbs, Richard ; Sanati, Souzan ; Vij, Kiran ; Watson, Mark ; Hahn, Olwen ; Guenther, Joseph ; Caudle, Abigail ; Crouch, Erika ; Tiersten, Amy ; Mita, Monica ; Razaq, Wajeeha ; Hieken, Tina J ; Wang, Yang ; Leitch, A. Marilyn ; Unzeitig, Gary W ; Weiss, Anna ; Winer, Eric P ; Hunt, Kelly ; Partridge, Ann H ; Carey, Lisa A ; Perou, Charles M ; Ellis, Matthew J ; Suman, Vera

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A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair

Pulver, Emilia M ; Mukherjee, Chirantani ; van de Kamp, Gerarda ; Roobol, Stefan J ; Rother, Magdalena B ; van der Gulden, Hanneke ; de Bruijn, Roebi ; Lattanzio, Maria Valeria ; van der Burg, Eline ; Drenth, Anne Paulien ; Verkaik, Nicole S ; Hahn, Kerstin ; Klarenbeek, Sjoerd ; de Korte-Grimmerink, Renske ; van de Ven, Marieke ; Pritchard, Colin E J ; Huijbers, Ivo J ; Xia, Bing ; van Gent, Dik C ; Essers, Jeroen ; van Attikum, Haico ; Ray Chaudhuri, Arnab ; Bouwman, Peter ; Jonkers, Jos

United States

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