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Material Type: Artigo
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The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNAFonfara, Ines ; Richter, Hagen ; Bratovič, Majda ; Le Rhun, Anaïs ; Charpentier, EmmanuelleNature (London), 2016-04, Vol.532 (7600), p.517-521 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12aSwarts, Daan C. ; van der Oost, John ; Jinek, MartinMolecular cell, 2017-04, Vol.66 (2), p.221-233.e4 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13aLiu, Liang ; Li, Xueyan ; Ma, Jun ; Li, Zongqiang ; You, Lilan ; Wang, Jiuyu ; Wang, Min ; Zhang, Xinzheng ; Wang, YanliCell, 2017-08, Vol.170 (4), p.714-726.e10 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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CRISPR-Cas9 Structures and MechanismsJiang, Fuguo ; Doudna, Jennifer AAnnual review of biophysics, 2017-05, Vol.46 (1), p.505-529 [Periódico revisado por pares]United States: Annual ReviewsTexto completo disponível |
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Material Type: Artigo
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Non‐Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co‐Delivery of Cas9 mRNA and sgRNAMiller, Jason B. ; Zhang, Shuyuan ; Kos, Petra ; Xiong, Hu ; Zhou, Kejin ; Perelman, Sofya S. ; Zhu, Hao ; Siegwart, Daniel J.Angewandte Chemie (International ed.), 2017-01, Vol.56 (4), p.1059-1063 [Periódico revisado por pares]Germany: Wiley Subscription Services, IncTexto completo disponível |
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Material Type: Artigo
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Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detectionEast-Seletsky, Alexandra ; O'Connell, Mitchell R ; Knight, Spencer C ; Burstein, David ; Cate, Jamie H D ; Tjian, Robert ; Doudna, Jennifer ANature (London), 2016-10, Vol.538 (7624), p.270-273 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1Yamano, Takashi ; Zetsche, Bernd ; Ishitani, Ryuichiro ; Zhang, Feng ; Nishimasu, Hiroshi ; Nureki, OsamuMolecular cell, 2017-08, Vol.67 (4), p.633-645.e3 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28Smargon, Aaron A. ; Cox, David B.T. ; Pyzocha, Neena K. ; Zheng, Kaijie ; Slaymaker, Ian M. ; Gootenberg, Jonathan S. ; Abudayyeh, Omar A. ; Essletzbichler, Patrick ; Shmakov, Sergey ; Makarova, Kira S. ; Koonin, Eugene V. ; Zhang, FengMolecular cell, 2017-02, Vol.65 (4), p.618-630.e7 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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The crystal structure of Cpf1 in complex with CRISPR RNADong, De ; Ren, Kuan ; Qiu, Xiaolin ; Zheng, Jianlin ; Guo, Minghui ; Guan, Xiaoyu ; Liu, Hongnan ; Li, Ningning ; Zhang, Bailing ; Yang, Daijun ; Ma, Chuang ; Wang, Shuo ; Wu, Dan ; Ma, Yunfeng ; Fan, Shilong ; Wang, Jiawei ; Gao, Ning ; Huang, ZhiweiNature (London), 2016-04, Vol.532 (7600), p.522-526 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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C2c1-sgRNA Complex Structure Reveals RNA-Guided DNA Cleavage MechanismLiu, Liang ; Chen, Peng ; Wang, Min ; Li, Xueyan ; Wang, Jiuyu ; Yin, Maolu ; Wang, YanliMolecular cell, 2017-01, Vol.65 (2), p.310-322 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |