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1
High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell–Derived Organoids
High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell–Derived Organoids
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High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell–Derived Organoids

Shinozawa, Tadahiro ; Kimura, Masaki ; Cai, Yuqi ; Saiki, Norikazu ; Yoneyama, Yosuke ; Ouchi, Rie ; Koike, Hiroyuki ; Maezawa, Mari ; Zhang, Ran-Ran ; Dunn, Andrew ; Ferguson, Autumn ; Togo, Shodai ; Lewis, Kyle ; Thompson, Wendy L. ; Asai, Akihiro ; Takebe, Takanori

Gastroenterology (New York, N.Y. 1943), 2021-02, Vol.160 (3), p.831-846.e10 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease
Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease
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Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease

Duan, Yi ; Llorente, Cristina ; Lang, Sonja ; Brandl, Katharina ; Chu, Huikuan ; Jiang, Lu ; White, Richard C ; Clarke, Thomas H ; Nguyen, Kevin ; Torralba, Manolito ; Shao, Yan ; Liu, Jinyuan ; Hernandez-Morales, Adriana ; Lessor, Lauren ; Rahman, Imran R ; Miyamoto, Yukiko ; Ly, Melissa ; Gao, Bei ; Sun, Weizhong ; Kiesel, Roman ; Hutmacher, Felix ; Lee, Suhan ; Ventura-Cots, Meritxell ; Bosques-Padilla, Francisco ; Verna, Elizabeth C ; Abraldes, Juan G ; Brown, Jr, Robert S ; Vargas, Victor ; Altamirano, Jose ; Caballería, Juan ; Shawcross, Debbie L ; Ho, Samuel B ; Louvet, Alexandre ; Lucey, Michael R ; Mathurin, Philippe ; Garcia-Tsao, Guadalupe ; Bataller, Ramon ; Tu, Xin M ; Eckmann, Lars ; van der Donk, Wilfred A ; Young, Ry ; Lawley, Trevor D ; Stärkel, Peter ; Pride, David ; Fouts, Derrick E ; Schnabl, Bernd

Nature (London), 2019-11, Vol.575 (7783), p.505-511 [Periódico revisado por pares]

England: Nature Publishing Group

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3
SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function
SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function
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SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

Price, Nathan L. ; Gomes, Ana P. ; Ling, Alvin J.Y. ; Duarte, Filipe V. ; Martin-Montalvo, Alejandro ; North, Brian J. ; Agarwal, Beamon ; Ye, Lan ; Ramadori, Giorgio ; Teodoro, Joao S. ; Hubbard, Basil P. ; Varela, Ana T. ; Davis, James G. ; Varamini, Behzad ; Hafner, Angela ; Moaddel, Ruin ; Rolo, Anabela P. ; Coppari, Roberto ; Palmeira, Carlos M. ; de Cabo, Rafael ; Baur, Joseph A. ; Sinclair, David A.

Cell metabolism, 2012-05, Vol.15 (5), p.675-690 [Periódico revisado por pares]

United States: Elsevier Inc

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4
De novo NAD + synthesis enhances mitochondrial function and improves health
De novo NAD + synthesis enhances mitochondrial function and improves health
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De novo NAD + synthesis enhances mitochondrial function and improves health

Katsyuba, Elena ; Mottis, Adrienne ; Zietak, Marika ; De Franco, Francesca ; van der Velpen, Vera ; Gariani, Karim ; Ryu, Dongryeol ; Cialabrini, Lucia ; Matilainen, Olli ; Liscio, Paride ; Giacchè, Nicola ; Stokar-Regenscheit, Nadine ; Legouis, David ; de Seigneux, Sophie ; Ivanisevic, Julijana ; Raffaelli, Nadia ; Schoonjans, Kristina ; Pellicciari, Roberto ; Auwerx, Johan

Nature (London), 2018-11, Vol.563 (7731), p.354-359 [Periódico revisado por pares]

England

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5
Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease
Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease
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Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Bell, Catherine C ; Hendriks, Delilah F G ; Moro, Sabrina M L ; Ellis, Ewa ; Walsh, Joanne ; Renblom, Anna ; Fredriksson Puigvert, Lisa ; Dankers, Anita C A ; Jacobs, Frank ; Snoeys, Jan ; Sison-Young, Rowena L ; Jenkins, Rosalind E ; Nordling, Åsa ; Mkrtchian, Souren ; Park, B Kevin ; Kitteringham, Neil R ; Goldring, Christopher E P ; Lauschke, Volker M ; Ingelman-Sundberg, Magnus

Scientific reports, 2016-05, Vol.6 (1), p.25187, Article 25187 [Periódico revisado por pares]

England: Nature Publishing Group

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6
Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex
Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex
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Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex

Howell, Jessica J. ; Hellberg, Kristina ; Turner, Marc ; Talbott, George ; Kolar, Matthew J. ; Ross, Debbie S. ; Hoxhaj, Gerta ; Saghatelian, Alan ; Shaw, Reuben J. ; Manning, Brendan D.

Cell metabolism, 2017-02, Vol.25 (2), p.463-471 [Periódico revisado por pares]

United States: Elsevier Inc

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7
Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
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Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

Cameron, Amy R ; Morrison, Vicky L ; Levin, Daniel ; Mohan, Mohapradeep ; Forteath, Calum ; Beall, Craig ; McNeilly, Alison D ; Balfour, David J.K ; Savinko, Terhi ; Wong, Aaron K.F ; Viollet, Benoit ; Sakamoto, Kei ; Fagerholm, Susanna C ; Foretz, Marc ; Lang, Chim C ; Rena, Graham

Circulation research, 2016-08, Vol.119 (5), p.652-665 [Periódico revisado por pares]

United States: American Heart Association, Inc

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8
Metformin Activates AMPK through the Lysosomal Pathway
Metformin Activates AMPK through the Lysosomal Pathway
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Metformin Activates AMPK through the Lysosomal Pathway

Zhang, Chen-Song ; Li, Mengqi ; Ma, Teng ; Zong, Yue ; Cui, Jiwen ; Feng, Jin-Wei ; Wu, Yu-Qing ; Lin, Shu-Yong ; Lin, Sheng-Cai

Cell metabolism, 2016-10, Vol.24 (4), p.521-522 [Periódico revisado por pares]

United States: Elsevier Inc

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9
Inflammatory pathways in alcoholic steatohepatitis
Inflammatory pathways in alcoholic steatohepatitis
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Inflammatory pathways in alcoholic steatohepatitis

Gao, Bin ; Ahmad, Maleeha F. ; Nagy, Laura E. ; Tsukamoto, Hidekazu

Journal of hepatology, 2019-02, Vol.70 (2), p.249-259 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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10
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
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Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Malehmir, Mohsen ; Pfister, Dominik ; Gallage, Suchira ; Szydlowska, Marta ; Inverso, Donato ; Kotsiliti, Elena ; Leone, Valentina ; Peiseler, Moritz ; Surewaard, Bas G J ; Rath, Dominik ; Ali, Adnan ; Wolf, Monika Julia ; Drescher, Hannah ; Healy, Marc E ; Dauch, Daniel ; Kroy, Daniela ; Krenkel, Oliver ; Kohlhepp, Marlene ; Engleitner, Thomas ; Olkus, Alexander ; Sijmonsma, Tjeerd ; Volz, Julia ; Deppermann, Carsten ; Stegner, David ; Helbling, Patrick ; Nombela-Arrieta, César ; Rafiei, Anahita ; Hinterleitner, Martina ; Rall, Marcel ; Baku, Florian ; Borst, Oliver ; Wilson, Caroline L ; Leslie, Jack ; O'Connor, Tracy ; Weston, Christopher J ; Chauhan, Abhishek ; Adams, David H ; Sheriff, Lozan ; Teijeiro, Ana ; Prinz, Marco ; Bogeska, Ruzhica ; Anstee, Natasha ; Bongers, Malte N ; Notohamiprodjo, Mike ; Geisler, Tobias ; Withers, Dominic J ; Ware, Jerry ; Mann, Derek A ; Augustin, Hellmut G ; Vegiopoulos, Alexandros ; Milsom, Michael D ; Rose, Adam J ; Lalor, Patricia F ; Llovet, Josep M ; Pinyol, Roser ; Tacke, Frank ; Rad, Roland ; Matter, Matthias ; Djouder, Nabil ; Kubes, Paul ; Knolle, Percy A ; Unger, Kristian ; Zender, Lars ; Nieswandt, Bernhard ; Gawaz, Meinrad ; Weber, Achim ; Heikenwalder, Mathias

Nature medicine, 2019-04, Vol.25 (4), p.641-655 [Periódico revisado por pares]

United States: Nature Publishing Group

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