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Material Type: Artículo
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Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cellsDev, Harveer ; Chiang, Ting-Wei Will ; Lescale, Chloe ; de Krijger, Inge ; Martin, Alistair G ; Pilger, Domenic ; Coates, Julia ; Sczaniecka-Clift, Matylda ; Wei, Wenming ; Ostermaier, Matthias ; Herzog, Mareike ; Lam, Jonathan ; Shea, Abigail ; Demir, Mukerrem ; Wu, Qian ; Yang, Fengtang ; Fu, Beiyuan ; Lai, Zhongwu ; Balmus, Gabriel ; Belotserkovskaya, Rimma ; Serra, Violeta ; O'Connor, Mark J ; Bruna, Alejandra ; Beli, Petra ; Pellegrini, Luca ; Caldas, Carlos ; Deriano, Ludovic ; Jacobs, Jacqueline J L ; Galanty, Yaron ; Jackson, Stephen PNature cell biology, 2018-08, Vol.20 (8), p.954-965 [Revista revisada por pares]England: Nature Publishing GroupTexto completo disponible |
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Material Type: Artículo
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PARP Inhibitors in the Management of Ovarian Cancer: ASCO GuidelineTew, William P ; Lacchetti, Christina ; Ellis, Annie ; Maxian, Kathleen ; Banerjee, Susana ; Bookman, Michael ; Jones, Monica Brown ; Lee, Jung-Min ; Lheureux, Stéphanie ; Liu, Joyce F ; Moore, Kathleen N ; Muller, Carolyn ; Rodriguez, Patricia ; Walsh, Christine ; Westin, Shannon N ; Kohn, Elise CJournal of clinical oncology, 2020-10, Vol.38 (30), p.3468-3493 [Revista revisada por pares]United StatesTexto completo disponible |
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Material Type: Artículo
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Overall Survival With Maintenance Olaparib at a 7-Year Follow-Up in Patients With Newly Diagnosed Advanced Ovarian Cancer and a BRCA Mutation: The SOLO1/GOG 3004 TrialDiSilvestro, Paul ; Banerjee, Susana ; Colombo, Nicoletta ; Scambia, Giovanni ; Kim, Byoung-Gie ; Oaknin, Ana ; Friedlander, Michael ; Lisyanskaya, Alla ; Floquet, Anne ; Leary, Alexandra ; Sonke, Gabe S ; Gourley, Charlie ; Oza, Amit ; González-Martín, Antonio ; Aghajanian, Carol ; Bradley, William ; Mathews, Cara ; Liu, Joyce ; McNamara, John ; Lowe, Elizabeth S ; Ah-See, Mei-Lin ; Moore, Kathleen NJournal of clinical oncology, 2023-01, Vol.41 (3), p.609-617 [Revista revisada por pares]United States: Wolters Kluwer HealthTexto completo disponible |
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Material Type: Artículo
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ESMO recommendations on predictive biomarker testing for homologous recombination deficiency and PARP inhibitor benefit in ovarian cancerMiller, R.E. ; Leary, A. ; Scott, C.L. ; Serra, V. ; Lord, C.J. ; Bowtell, D. ; Chang, D.K. ; Garsed, D.W. ; Jonkers, J. ; Ledermann, J.A. ; Nik-Zainal, S. ; Ray-Coquard, I. ; Shah, S.P. ; Matias-Guiu, X. ; Swisher, E.M. ; Yates, L.R.Annals of oncology, 2020-12, Vol.31 (12), p.1606-1622 [Revista revisada por pares]England: Elsevier LtdTexto completo disponible |
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Material Type: Artículo
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A Randomized, Phase III Trial to Evaluate Rucaparib Monotherapy as Maintenance Treatment in Patients With Newly Diagnosed Ovarian Cancer (ATHENA-MONO/GOG-3020/ENGOT-ov45)Monk, Bradley J ; Parkinson, Christine ; Lim, Myong Cheol ; O'Malley, David M ; Oaknin, Ana ; Wilson, Michelle K ; Coleman, Robert L ; Lorusso, Domenica ; Bessette, Paul ; Ghamande, Sharad ; Christopoulou, Athina ; Provencher, Diane ; Prendergast, Emily ; Demirkiran, Fuat ; Mikheeva, Olga ; Yeku, Oladapo ; Chudecka-Glaz, Anita ; Schenker, Michael ; Littell, Ramey D ; Safra, Tamar ; Chou, Hung-Hsueh ; Morgan, Mark A ; Drochýtek, Vít ; Barlin, Joyce N ; Van Gorp, Toon ; Ueland, Fred ; Lindahl, Gabriel ; Anderson, Charles ; Collins, Dearbhaile C ; Moore, Kathleen ; Marme, Frederik ; Westin, Shannon N ; McNeish, Iain A ; Shih, Danny ; Lin, Kevin K ; Goble, Sandra ; Hume, Stephanie ; Fujiwara, Keiichi ; Kristeleit, Rebecca SJournal of clinical oncology, 2022-12, Vol.40 (34), p.3952-3964 [Revista revisada por pares]United States: Wolters Kluwer HealthTexto completo disponible |
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Material Type: Artículo
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Restoring Anticancer Immune Response by Targeting Tumor-Derived Exosomes With a HSP70 Peptide AptamerGobbo, Jessica ; Marcion, Guillaume ; Cordonnier, Marine ; Dias, Alexandre M M ; Pernet, Nicolas ; Hammann, Arlette ; Richaud, Sarah ; Mjahed, Hajare ; Isambert, Nicolas ; Clausse, Victor ; Rébé, Cédric ; Bertaut, Aurélie ; Goussot, Vincent ; Lirussi, Frédéric ; Ghiringhelli, François ; de Thonel, Aurélie ; Fumoleau, Pierre ; Seigneuric, Renaud ; Garrido, CarmenJNCI : Journal of the National Cancer Institute, 2016-03, Vol.108 (3), p.djv330 [Revista revisada por pares]United States: Oxford University Press (OUP)Texto completo disponible |
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Material Type: Artículo
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Niraparib in Patients with Newly Diagnosed Advanced Ovarian CancerGonzález-Martín, Antonio ; Pothuri, Bhavana ; Vergote, Ignace ; DePont Christensen, René ; Graybill, Whitney ; Mirza, Mansoor R ; McCormick, Colleen ; Lorusso, Domenica ; Hoskins, Paul ; Freyer, Gilles ; Baumann, Klaus ; Jardon, Kris ; Redondo, Andrés ; Moore, Richard G ; Vulsteke, Christof ; O’Cearbhaill, Roisin E ; Lund, Bente ; Backes, Floor ; Barretina-Ginesta, Pilar ; Haggerty, Ashley F ; Rubio-Pérez, Maria J ; Shahin, Mark S ; Mangili, Giorgia ; Bradley, William H ; Bruchim, Ilan ; Sun, Kaiming ; Malinowska, Izabela A ; Li, Yong ; Gupta, Divya ; Monk, Bradley JThe New England journal of medicine, 2019-12, Vol.381 (25), p.2391-2402 [Revista revisada por pares]United States: Massachusetts Medical SocietyTexto completo disponible |
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Material Type: Artículo
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Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trialPujade-Lauraine, Eric ; Ledermann, Jonathan A ; Selle, Frédéric ; Gebski, Val ; Penson, Richard T ; Oza, Amit M ; Korach, Jacob ; Friedlander, Michael ; Colombo, Nicoletta ; Harter, Philipp ; Fujiwara, Keiichi ; Ray-Coquard, Isabelle ; Banerjee, Susana ; Liu, Joyce ; Lowe, Elizabeth S ; Bloomfield, Ralph ; Pautier, Patricia ; Korach, Jacob ; Huzarski, Tomasz ; Byrski, Tomasz ; Pautier, Patricia ; Friedlander, Michael ; Harter, Philipp ; Colombo, Nicoletta ; Scambia, Giovanni ; Nicoletto, Maria ; Nussey, Fiona ; Clamp, Andrew ; Penson, Richard ; Oza, Amit ; Poveda Velasco, Andrés ; Rodrigues, Manuel ; Lotz, Jean-Pierre ; Selle, Frédéric ; Ray-Coquard, Isabelle ; Provencher, Diane ; Prat Aparicio, Aleix ; Vidal Boixader, Laura ; Scott, Clare ; Tamura, Kenji ; Yunokawa, Mayu ; Lisyanskaya, Alla ; Medioni, Jacques ; Pécuchet, Nicolas ; de la Motte Rouge, Thibault ; Lortholary, Alain ; Williams, Sarah ; Cosin, Jonathan ; Hoffman, James ; Plante, Marie ; Covens, Allan ; Sonke, Gabe ; Joly, Florence ; Hirte, Holger ; Park-Simon, Tjoung-Won ; Tjulandin, Sergei ; Kim, Jae Hoon ; Gladieff, Laurence ; Sabbatini, Roberto ; Timmins, Patrick ; Kredentser, Daniel ; Laínez Milagro, Nuria ; Barretina Ginesta, Maria Pilar ; Tibau Martorell, Ariadna ; Gómez de Liaño Lista, Alfonso ; Ojeda González, Belén ; Mileshkin, Linda ; Mandai, Masaki ; Boere, Ingrid ; Ottevanger, Petronella ; Nam, Joo-Hyun ; Filho, Elias ; Hamizi, Salima ; Dickson-Michelson, Elizabeth ; Kamelle, Scott ; McKenzie, Nathalie ; Rodriguez, Gustavo ; Armstrong, Deborah ; Chalas, Eva ; Celano, Paul ; Davidson, Susan ; Welch, Stephen ; Fishman, Ami ; Bruchim, Ilan ; Sikorska, Magdalena ; Słowińska, Anna ; Rogowski, Wojciech ; Bidziński, Mariusz ; Śpiewankiewicz, Beata ; Casado Herraez, Antonio ; Mendiola Fernández, César ; Gropp-Meier, Martina ; Saito, Toshiaki ; Takehara, Kazuhiro ; Enomoto, Takayuki ; Watari, Hidemichi ; Choi, Chel Hun ; Kim, Byoung-Gie ; Kim, Jae Weon ; Vergote, IgnaceThe lancet oncology, 2017-09, Vol.18 (9), p.1274-1284 [Revista revisada por pares]England: Elsevier LtdTexto completo disponible |
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Material Type: Artículo
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Standard first-line chemotherapy with or without nintedanib for advanced ovarian cancer (AGO-OVAR 12): a randomised, double-blind, placebo-controlled phase 3 trialdu Bois, Andreas, Prof ; Kristensen, Gunnar, Prof ; Ray-Coquard, Isabelle, Prof ; Reuss, Alexander, MSc ; Pignata, Sandro, MD ; Colombo, Nicoletta, Prof ; Denison, Ursula, MD ; Vergote, Ignace, Prof ; del Campo, Jose M, MD ; Ottevanger, Petronella, PhD ; Heubner, Martin, MD ; Minarik, Thomas, PhD ; Sevin, Emmanuel, MD ; de Gregorio, Nikolaus, MD ; Bidziński, Mariusz, Prof ; Pfisterer, Jacobus, Prof ; Malander, Susanne, MD ; Hilpert, Felix, Prof ; Mirza, Mansoor R, MD ; Scambia, Giovanni, Prof ; Meier, Werner, Prof ; Nicoletto, Maria O, MD ; Bjørge, Line, Prof ; Lortholary, Alain, MD ; Sailer, Martin Oliver, PhD ; Merger, Michael, MD ; Harter, Philipp, MDThe lancet oncology, 2016, Vol.17 (1), p.78-89 [Revista revisada por pares]England: Elsevier LtdTexto completo disponible |
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Material Type: Artículo
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An organoid platform for ovarian cancer captures intra- and interpatient heterogeneityKopper, Oded ; de Witte, Chris J ; Lõhmussaar, Kadi ; Valle-Inclan, Jose Espejo ; Hami, Nizar ; Kester, Lennart ; Balgobind, Anjali Vanita ; Korving, Jeroen ; Proost, Natalie ; Begthel, Harry ; van Wijk, Lise M ; Revilla, Sonia Aristín ; Theeuwsen, Rebecca ; van de Ven, Marieke ; van Roosmalen, Markus J ; Ponsioen, Bas ; Ho, Victor W H ; Neel, Benjamin G ; Bosse, Tjalling ; Gaarenstroom, Katja N ; Vrieling, Harry ; Vreeswijk, Maaike P G ; van Diest, Paul J ; Witteveen, Petronella O ; Jonges, Trudy ; Bos, Johannes L ; van Oudenaarden, Alexander ; Zweemer, Ronald P ; Snippert, Hugo J G ; Kloosterman, Wigard P ; Clevers, HansNature medicine, 2019-05, Vol.25 (5), p.838-849 [Revista revisada por pares]United States: Nature Publishing GroupTexto completo disponible |