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1 |
Material Type: Artigo
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Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain bindingZhong, Franklin L. ; Robinson, Kim ; Teo, Daniel Eng Thiam ; Tan, Kiat-Yi ; Lim, Chrissie ; Harapas, Cassandra R. ; Yu, Chien-Hsiung ; Xie, William H. ; Sobota, Radoslaw M. ; Au, Veonice Bijin ; Hopkins, Richard ; D'Osualdo, Andrea ; Reed, John C. ; Connolly, John E. ; Masters, Seth L. ; Reversade, BrunoThe Journal of biological chemistry, 2018-12, Vol.293 (49), p.18864-18878 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Deficiency in coatomer complex I causes aberrant activation of STING signallingSteiner, Annemarie ; Hrovat-Schaale, Katja ; Prigione, Ignazia ; Yu, Chien-Hsiung ; Laohamonthonkul, Pawat ; Harapas, Cassandra R ; Low, Ronnie Ren Jie ; De Nardo, Dominic ; Dagley, Laura F ; Mlodzianoski, Michael J ; Rogers, Kelly L ; Zillinger, Thomas ; Hartmann, Gunther ; Gantier, Michael P ; Gattorno, Marco ; Geyer, Matthias ; Volpi, Stefano ; Davidson, Sophia ; Masters, Seth LNature communications, 2022-04, Vol.13 (1), p.2321-2321, Article 2321 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALSYu, Chien-Hsiung ; Davidson, Sophia ; Harapas, Cassandra R. ; Hilton, James B. ; Mlodzianoski, Michael J. ; Laohamonthonkul, Pawat ; Louis, Cynthia ; Low, Ronnie Ren Jie ; Moecking, Jonas ; De Nardo, Dominic ; Balka, Katherine R. ; Calleja, Dale J. ; Moghaddas, Fiona ; Ni, Erya ; McLean, Catriona A. ; Samson, Andre L. ; Tyebji, Shiraz ; Tonkin, Christopher J. ; Bye, Christopher R. ; Turner, Bradley J. ; Pepin, Genevieve ; Gantier, Michael P. ; Rogers, Kelly L. ; McArthur, Kate ; Crouch, Peter J. ; Masters, Seth L.Cell, 2020-10, Vol.183 (3), p.636-649.e18 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Organellar homeostasis and innate immune sensingHarapas, Cassandra R ; Idiiatullina, Elina ; Al-Azab, Mahmoud ; Hrovat-Schaale, Katja ; Reygaerts, Thomas ; Steiner, Annemarie ; Laohamonthonkul, Pawat ; Davidson, Sophia ; Yu, Chien-Hsiung ; Booty, Lee ; Masters, Seth LNature reviews. Immunology, 2022-09, Vol.22 (9), p.535-549 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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An Update on Autoinflammatory Diseases: InterferonopathiesDavidson, Sophia ; Steiner, Annemarie ; Harapas, Cassandra R. ; Masters, Seth L.Current rheumatology reports, 2018-07, Vol.20 (7), p.38-38, Article 38 [Periódico revisado por pares]New York: Springer USTexto completo disponível |
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Material Type: Artigo
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An Update on Autoinflammatory Diseases: InflammasomopathiesHarapas, Cassandra R. ; Steiner, Annemarie ; Davidson, Sophia ; Masters, Seth L.Current rheumatology reports, 2018-07, Vol.20 (7), p.40-40, Article 40 [Periódico revisado por pares]New York: Springer USTexto completo disponível |
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Material Type: Artigo
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An Update on Autoinflammatory Diseases: RelopathiesSteiner, Annemarie ; Harapas, Cassandra R. ; Masters, Seth L. ; Davidson, SophiaCurrent rheumatology reports, 2018-07, Vol.20 (7), p.39-39, Article 39 [Periódico revisado por pares]New York: Springer USTexto completo disponível |
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Material Type: Artigo
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ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasomeRobinson, Kim S ; Toh, Gee Ann ; Rozario, Pritisha ; Chua, Rae ; Bauernfried, Stefan ; Sun, Zijin ; Firdaus, Muhammad Jasrie ; Bayat, Shima ; Nadkarni, Rhea ; Poh, Zhi Sheng ; Tham, Khek Chian ; Harapas, Cassandra R ; Lim, Chrissie K ; Chu, Werncui ; Tay, Celest W S ; Tan, Kiat Yi ; Zhao, Tianyun ; Bonnard, Carine ; Sobota, Radoslaw ; Connolly, John E ; Common, John ; Masters, Seth L ; Chen, Kaiwen W ; Ho, Lena ; Wu, Bin ; Hornung, Veit ; Zhong, Franklin LScience (American Association for the Advancement of Science), 2022-07, Vol.377 (6603), p.328-335 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domainMoecking, Jonas ; Laohamonthonkul, Pawat ; Meşe, Kubilay ; Hagelueken, Gregor ; Steiner, Annemarie ; Harapas, Cassandra R. ; Sandow, Jarrod J. ; Graves, Jonathan D. ; Masters, Seth L. ; Geyer, MatthiasThe Journal of biological chemistry, 2022-12, Vol.298 (12), p.102645-102645, Article 102645 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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FGFR3-TACC3 is an oncogenic fusion protein in respiratory epitheliumBest, Sarah A ; Harapas, Cassandra R ; Kersbergen, Ariena ; Rathi, Vivek ; Asselin-Labat, Marie-Liesse ; Sutherland, Kate DOncogene, 2018-11, Vol.37 (46), p.6096-6104 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |