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Fruitful Neutralizing Antibody Pipeline Brings Hope To Defeat SARS-Cov-2
Fruitful Neutralizing Antibody Pipeline Brings Hope To Defeat SARS-Cov-2
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Fruitful Neutralizing Antibody Pipeline Brings Hope To Defeat SARS-Cov-2

Renn, Alex ; Fu, Ying ; Hu, Xin ; Hall, Matthew D. ; Simeonov, Anton

Trends in pharmacological sciences (Regular ed.), 2020-11, Vol.41 (11), p.815-829 [Periódico revisado por pares]

England: Elsevier Ltd

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Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19
Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19
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Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19

Eastman, Richard T ; Roth, Jacob S ; Brimacombe, Kyle R ; Simeonov, Anton ; Shen, Min ; Patnaik, Samarjit ; Hall, Matthew D

ACS central science, 2020-05, Vol.6 (5), p.672-683

American Chemical Society

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3
Drug discovery and development for rare genetic disorders
Drug discovery and development for rare genetic disorders
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Drug discovery and development for rare genetic disorders

Sun, Wei ; Zheng, Wei ; Simeonov, Anton

American journal of medical genetics. Part A, 2017-09, Vol.173 (9), p.2307-2322 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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4
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
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Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

Xu, Miao ; Lee, Emily M ; Wen, Zhexing ; Cheng, Yichen ; Huang, Wei-Kai ; Qian, Xuyu ; Tcw, Julia ; Kouznetsova, Jennifer ; Ogden, Sarah C ; Hammack, Christy ; Jacob, Fadi ; Nguyen, Ha Nam ; Itkin, Misha ; Hanna, Catherine ; Shinn, Paul ; Allen, Chase ; Michael, Samuel G ; Simeonov, Anton ; Huang, Wenwei ; Christian, Kimberly M ; Goate, Alison ; Brennand, Kristen J ; Huang, Ruili ; Xia, Menghang ; Ming, Guo-Li ; Zheng, Wei ; Song, Hongjun ; Tang, Hengli

Nature medicine, 2016-10, Vol.22 (10), p.1101-1107 [Periódico revisado por pares]

United States: Nature Publishing Group

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5
Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics
Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics
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Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics

Zhu, Hu ; Chen, Catherine Z ; Sakamuru, Srilatha ; Zhao, Jinghua ; Ngan, Deborah K ; Simeonov, Anton ; Hall, Mathew D ; Xia, Menghang ; Zheng, Wei ; Huang, Ruili

Scientific reports, 2021-03, Vol.11 (1), p.6725-6725, Article 6725 [Periódico revisado por pares]

England: Nature Publishing Group

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6
TCRD and Pharos 2021: mining the human proteome for disease biology
TCRD and Pharos 2021: mining the human proteome for disease biology
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TCRD and Pharos 2021: mining the human proteome for disease biology

Sheils, Timothy K ; Mathias, Stephen L ; Kelleher, Keith J ; Siramshetty, Vishal B ; Nguyen, Dac-Trung ; Bologa, Cristian G ; Jensen, Lars Juhl ; Vidović, Dušica ; Koleti, Amar ; Schürer, Stephan C ; Waller, Anna ; Yang, Jeremy J ; Holmes, Jayme ; Bocci, Giovanni ; Southall, Noel ; Dharkar, Poorva ; Mathé, Ewy ; Simeonov, Anton ; Oprea, Tudor I

Nucleic acids research, 2021-01, Vol.49 (D1), p.D1334-D1346 [Periódico revisado por pares]

England: Oxford University Press

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7
Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses
Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses
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Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses

Jaynes, Jesse M ; Sable, Rushikesh ; Ronzetti, Michael ; Bautista, Wendy ; Knotts, Zachary ; Abisoye-Ogunniyan, Abisola ; Li, Dandan ; Calvo, Raul ; Dashnyam, Myagmarjav ; Singh, Anju ; Guerin, Theresa ; White, Jason ; Ravichandran, Sarangan ; Kumar, Parimal ; Talsania, Keyur ; Chen, Vicky ; Ghebremedhin, Anghesom ; Karanam, Balasubramanyam ; Bin Salam, Ahmad ; Amin, Ruksana ; Odzorig, Taivan ; Aiken, Taylor ; Nguyen, Victoria ; Bian, Yansong ; Zarif, Jelani C ; de Groot, Amber E ; Mehta, Monika ; Fan, Lixin ; Hu, Xin ; Simeonov, Anton ; Pate, Nathan ; Abu-Asab, Mones ; Ferrer, Marc ; Southall, Noel ; Ock, Chan-Young ; Zhao, Yongmei ; Lopez, Henry ; Kozlov, Serguei ; de Val, Natalia ; Yates, Clayton C ; Baljinnyam, Bolormaa ; Marugan, Juan ; Rudloff, Udo

Science translational medicine, 2020-02, Vol.12 (530), p.1 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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8
Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization
Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization
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Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization

Huang, Ruili ; Xia, Menghang ; Sakamuru, Srilatha ; Zhao, Jinghua ; Shahane, Sampada A ; Attene-Ramos, Matias ; Zhao, Tongan ; Austin, Christopher P ; Simeonov, Anton

Nature communications, 2016-01, Vol.7 (1), p.10425-10, Article 10425 [Periódico revisado por pares]

England: Nature Publishing Group

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9
The NCATS BioPlanet - An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics
The NCATS BioPlanet - An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics
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The NCATS BioPlanet - An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics

Huang, Ruili ; Grishagin, Ivan ; Wang, Yuhong ; Zhao, Tongan ; Greene, Jon ; Obenauer, John C ; Ngan, Deborah ; Nguyen, Dac-Trung ; Guha, Rajarshi ; Jadhav, Ajit ; Southall, Noel ; Simeonov, Anton ; Austin, Christopher P

Frontiers in pharmacology, 2019-04, Vol.10, p.445-445 [Periódico revisado por pares]

Switzerland: Frontiers Media S.A

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10
Pharos: Collating protein information to shed light on the druggable genome
Pharos: Collating protein information to shed light on the druggable genome
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Pharos: Collating protein information to shed light on the druggable genome

Nguyen, Dac-Trung ; Mathias, Stephen ; Bologa, Cristian ; Brunak, Soren ; Fernandez, Nicolas ; Gaulton, Anna ; Hersey, Anne ; Holmes, Jayme ; Jensen, Lars Juhl ; Karlsson, Anneli ; Liu, Guixia ; Ma'ayan, Avi ; Mandava, Geetha ; Mani, Subramani ; Mehta, Saurabh ; Overington, John ; Patel, Juhee ; Rouillard, Andrew D ; Schürer, Stephan ; Sheils, Timothy ; Simeonov, Anton ; Sklar, Larry A ; Southall, Noel ; Ursu, Oleg ; Vidovic, Dusica ; Waller, Anna ; Yang, Jeremy ; Jadhav, Ajit ; Oprea, Tudor I ; Guha, Rajarshi

Nucleic acids research, 2017-01, Vol.45 (D1), p.D995-D1002 [Periódico revisado por pares]

England: Oxford University Press

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